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Computer-based brief intervention for perinatal drug, alcohol, and tobacco abuse

针对围产期药物、酒精和烟草滥用的基于计算机的简短干预

基本信息

批准号：
7600615
负责人：
STEVEN J. ONDERSMA
金额：
$ 29.73万
依托单位：
WAYNE STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
起止时间：
2006-05-10 至 2011-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7600615
关键词：
Abstinence Address Affect Alcohol abuse Alcohol or Other Drugs use Alcohols Anger Arts Asthma Attention Behavior Therapy Blinded Breath Tests Brestan Caring Child Clinical Trials Cocaine Collaborations Communities Computer software Computers Conduct Disorder Control Groups Data Data Analyses Discipline of obstetrics Drug abuse Drug usage Financial cost HIV Hair Health Home environment Hospitals Illicit Drugs Individual Infant Intervention Language Lead Measures Mediating Mediator of activation protein Medical Methods Mothers Motivation Opiates Outcome Participant Patient Self-Report Perinatal Persons Pharmaceutical Preparations Population Postpartum Women Primary Health Care Provider Psychopathology Public Health Randomized Readiness Recruitment Activity Reporting Research Research Personnel Risk Risk Behaviors Risk-Taking Sampling Screening procedure Smoke Smoking Staging Substance abuse problem System Testing Time Tobacco Tobacco use Training Treatment Cost Urine Violence Woman base brief intervention brief motivational intervention cost experience facsimile follow up assessment follow-up high risk interest intervention effect intimate partner violence motivational enhancement therapy motivational intervention neglect prenatal smoking programs social software development stem substance abuse brief intervention theories therapy development tobacco abuse treatment program ward

项目摘要

DESCRIPTION (provided by applicant): The health-related, social, and financial costs of drug abuse are well-known; these costs are only multiplied when perinatal drug use and associated risks (such as HIV) also place an infant at risk, both prenatally and postnatally. A range of relevant treatment programs exist, but such programs are not able to either reach all women who are in need of treatment, or to engage many of those they do identify and intend to treat. Even brief motivational interventions in primary care - despite tremendous promise - are limited by the amount of time, training, expertise, and interest they require from primary care providers. In contrast, computer-based brief interventions could allow access to high proportions of women using drugs during the perinatal period. Computers could also do so at very low cost, and with perfect replication in the community. A computer-based brief motivational intervention developed under a Stage I R21 has shown early promise: at 3-month follow-up in a preliminary clinical trial, postpartum women randomly assigned to a 20-minute computer-based brief intervention were 3 times less likely to be using either cocaine, other stimulants, or opiates. In this Stage II application, this research will be expanded in two ways. First, the intervention will be modified based on data from the preliminary clinical trial, and tested in a larger sample of drug-using postpartum women. Second, the intervention will be extended to also address problem alcohol use and prenatal smoking. Specifically, this research will: (a) revise and upgrade software based on data from the initial clinical trial; (b) recruit 500 post-partum women (200 screening positive for illicit drug use, 150 screening positive for problem alcohol abuse, and 150 screening positive for smoking) from an urban obstetric hospital; and (c) randomly assign women into intervention and control conditions, with blinded follow-up assessments at 3- and 6-months. In addition to testing the effect of the intervention on substance use outcomes (as measured by self-report and toxicological analysis) and related outcomes (such as HIV risk), data analyses will also examine theory-driven mediators and moderators of any observed association between the brief intervention and outcomes. This research could enhance public health by making available an effective, practical, low-cost, and high-reach intervention for all forms of perinatal substance abuse.

描述(由申请人提供)：药物滥用的健康、社会和经济成本是众所周知的；只有当围产期药物使用和相关风险(如艾滋病毒)也将婴儿置于产前和出生后的风险中时，这些成本才会成倍增加。有一系列相关的治疗方案，但这些方案既不能惠及所有需要治疗的妇女，也不能吸引他们确定并打算治疗的许多人。即使是初级保健方面的简短激励性干预--尽管前景广阔--也受到初级保健提供者所需的时间、培训、专业知识和兴趣的限制。相比之下，基于计算机的短暂干预可以使高比例的妇女在围产期使用药物。计算机也可以以非常低的成本做到这一点，并在社区中进行完美的复制。在第一阶段R21下开发的一种基于计算机的短暂动机干预已经显示出早期的希望：在初步临床试验中，在3个月的随访中，随机分配到20分钟基于计算机的短暂干预的产后妇女使用可卡因、其他兴奋剂或鸦片类药物的可能性降低了3倍。在第二阶段的应用中，这项研究将从两个方面展开。首先，干预措施将根据初步临床试验的数据进行修改，并在产后使用药物的妇女中进行更大样本的测试。其次，干预措施将扩大到解决酒精使用和产前吸烟的问题。具体地说，这项研究将：(A)根据初步临床试验的数据修订和升级软件；(B)从一家城市产科医院招募500名产后妇女(200名非法药物使用筛查阳性，150名问题酗酒筛查阳性，150名吸烟筛查阳性)；(C)随机将妇女分配到干预和对照条件下，在3个月和6个月时进行盲法跟踪评估。除了测试干预对物质使用结果(通过自我报告和毒理学分析衡量)和相关结果(如艾滋病毒风险)的影响外，数据分析还将检查短暂干预和结果之间任何观察到的关联的理论驱动的调解人和调解人。这项研究可以通过为所有形式的围产期药物滥用提供有效、实用、低成本和覆盖范围广的干预措施来促进公共健康。