Outreach Core

项目摘要 对癌症系统治疗中心（CAST）的长期影响至关重要的是一个强大而包容的 外联工作。CastOutreach在2016-2022年建立的社区和计算基础设施 将作为拟议的核心ForCastT（外展为CastT）的基础，以满足教育 和癌症系统生物学联盟（CSBC）提出的外展挑战。Forcast将扩大 CastOutreach的范围是：1）通过教程开发可广泛访问的容器化软件环境， CastT工具的案例研究; 2）与癌症研究人员和临床医生建立新的伙伴关系; 3）培养 下一代促进多样性的科学家; 3）加强与来自 在STEM学科中代表性不足;以及4）更普遍地促进科学中的系统方法。 ForCAST的总体使命将通过其具体目标协同实现：1）WebCAST（Web- 基于Casts资源），用于将联合收割机Casts出版物和资源结合在一起的在线容器化软件包 通过文档和视频教程、特定领域的案例研究和计算工作流， 传播和采用; 2）WebCast-High（面向高中生的WebCast-High）， 来自纽约、洛杉矶和底特律九所高中的学生，对癌症数据进行了探索性分析， 计算系统生物学; 3）BroadCastT（广泛访问的CAST研究），用于装备来自 布鲁克林学院，在哥伦比亚大学进行研究生培训，并在生物医学部门就业; 4）StudioCAST（工作室艺术 在卡斯特）为创造视觉语言之间的科学和艺术的交叉点，提供新颖的学习 观点，并将与癌症诊断相关的经验明显地翻译给研究人员， 学生;和5）CaSTanet（CaST包容性网络），用于指导博士后科学家，提供 公平的机会，在他们未来的角色在学术机构作为教员，教师，实验室主任， 导师和评论家。 ForCAST已经建立了关键的合作伙伴关系，以支持拟议的活动，包括1）资源 与CSBC和更广泛的哥伦比亚社区（如哥伦比亚大学癌症研究中心）分享 职业提升核心（CRCE）; 2）与哥伦比亚大学和布鲁克林学院合作 研究经验保护伞（CURE）; 3）通过哥伦比亚研究经验保护伞和 Palazzo-Strozzi基金会;以及4）创建一个新的CSBC工作组-用科学导航癌症 ForCAST成功的基础是差异化学习和形成性学习的战略。 评估，这将确保CAST研究产品和基本概念和所需的技能， 理解它们，通过各种工具共享，以最大限度地吸引科学家，临床医生， 和学生

Project Summary Crucial to the long-lasting impact of the Center for Cancer Systems Therapeutics (CaST) is a robust and inclusive Outreach effort. The community and computational infrastructure established by CaST Outreach in 2016-2022 will be leveraged as the foundation for the proposed core ForCaST (outreach For CaST) to meet the education and outreach challenges put forth by the Cancer Systems Biology Consortium (CSBC). ForCaST will expand the scope of CaST Outreach to 1) develop widely accessible containerized software environments with tutorials and case studies for CaST tools; 2) forge new partnerships with cancer researchers and clinicians; 3) cultivate the next generation of diversity-promoting scientists; 3) strengthen connections with students from groups that are underrepresented in STEM disciplines; and 4) foster systems approaches in science more generally. The overall mission of ForCaST will be realized synergistically through its Specific Aims: 1) WebCaST (Web- based CaST resources) for online containerized packages that will combine CaST publications and resources with documented and video tutorials, domain-specific case studies, and computational workflows to facilitate dissemination and adoption; 2) WebCaST-High (WebCaST for high school students) that will introduce high- school students from nine high schools in NYC, LA, and Detroit, to exploratory analysis of cancer data and computational systems biology; 3) BroadCaST (Broadly accessible CaST research) for equipping students from Brooklyn College for graduate training at Columbia and careers in biomedical sectors; 4) StudioCaST (Studio art in CaST) for the creation of Visual Language at the intersection between Science and Art to offer novel learning perspectives and to palpably translate experiences associated with a cancer diagnosis to researchers and students; and 5) CaSTanet (CaST networks for inclusion) for mentoring postdoctoral scientists to provide equitable opportunities in their future roles at academic institutions as faculty members, instructors, lab heads, mentors, and reviewers. ForCaST has already established key partnerships to support the proposed activities including 1) resource sharing with the CSBC and broader Columbia communities such as the Columbia University Cancer Research Career Enhancement Core (CRCE); 2) collaborations with Columbia University and Brooklyn College Continuing Umbrella of Research Experiences (CURE); 3) partnerships with high schools through Columbia CURE and the Palazzo-Strozzi Foundation; and 4) the creation of a new CSBC working group – Navigating Cancer with Science and Art. Foundational to the success of ForCaST is a strategy of differentiated learning and formative assessment that will ensure that CaST research products and the underlying concepts and skills required to comprehend them, are shared through a variety of vehicles in order to maximize appeal to scientists, clinicians, and students.