Administrative Core

摘要/摘要：管理核心 我们建议的斯坦福癌症系统生物学中心(CCSB)的行政核心将提供 为与我们中心相关的所有协调活动提供后勤支持。它将在一个组织下运作 促进我们研究中心和其他NIH所有组件之间的通信和访问的结构 CSBC研究中心，NIH CSBC项目工作人员，以及拟议的U24协调中心。在内部， 我们的CCSB将有一个执行委员会、指导委员会和内部咨询委员会(IAB)来监督 我们中心的科学、培训和外展活动，并确保我们的总体目标和具体目标 都被满足了。我们的执行委员会将由我们的MPI领导，他们成功地领导了我们的CCSB计划 在过去五年中，在我们中心数据经理的支持下，他将负责协调 生物武器和数据核心的管理，并确保全面管理数据生成以及前后 处理和共享，以及我们的中心管理员，他们将监控和执行日常管理中心 行动。我们的指导委员会将由核心领导和联合领导、项目领导和联合领导组成。 销售线索和数据中心经理。IAB将为我们的中心提供科学建议， 一般评价，并解决与我们的年度现场审查相关的具体问题。此外，我们还将建立 由关键顾问组成的外部顾问委员会(EAB)，受益于他们在复杂环境方面的丰富经验 转移进展中与肿瘤-免疫-间质相互作用相关的系统生物学问题。为了 扩大我们的调查人员网络，我们的行政核心将促进我们提议的中心内试点项目 在计划的1-5年和2-5年的跨联盟项目中。我们的行政核心将协调 征集、申请和审查程序。这些试点项目将根据以下标准进行评估和奖励 科学价值，目的是培养与我们的科学主题相一致的新的研究途径 研究中心。跨财团项目将获得资助，以增加以下研究机会 财团成员之间的协作和互动努力。行政核心将致力于 促进数据科学研究环境中的公平、多样性和包容性，并提供培训 为少数群体和代表性不足的社区提供机会。最后，我们的行政核心将促进 斯坦福CCSB研究、培训和外展目标进展年度科学评论 外部咨询委员会和国家癌症研究所。

ABSTRACT/SUMMARY: Administrative Core The Administrative Core of our proposed Stanford Center for Cancer Systems Biology (CCSB) will provide the logistical support for all coordinated activities related to our Center. It will operate under an organizational structure that facilitates communication and access across all components of our Research Center, other NIH CSBC Research Centers, the NIH CSBC Program staff, and the proposed U24 Coordinating Center. Internally, our CCSB will have an Executive Committee, Steering Committee, and Internal Advisory Board (IAB) to oversee the scientific, training, and outreach activities of our Center and ensure that our overall goals and specific aims are being met. Our Executive Committee will be led by our MPIs, who have successfully led our CCSB program over the past five years, along with the support of our Center Data Manager, who will oversee the coordination of the Biospecimen and Data Core and ensure overall management of data generation and pre- and post- processing and sharing, and our Center Administrator, who will monitor and execute daily administrative center operations. Our Steering Committee will be composed of the Core Leads and co-Leads, Project Leads and co- Leads, and the Data Center Manager. The IAB will be available to provide our Center with scientific advice, general evaluation, and address specific issues related to our annual site review. Additionally, we will establish an External Advisory Board (EAB) of key advisors to benefit from their extensive experience relevant to complex systems biology issues related to tumor-immune-stromal interactions in metastatic progression. In order to expand our network of investigators, our Administrative Core will facilitate our proposed Intra-center Pilot Project in Years 1-5 and Cross-Consortium Project in Years 2-5 of the program. Our Administrative Core will coordinate the solicitation, application and review processes. These pilot projects will be evaluated and awarded based on scientific merit with the aim of fostering new avenues of research aligned with the scientific theme of our Research Center. The cross-consortium projects will be funded to increase research opportunities for collaborative and interactive efforts among members of the consortium. The Administrative Core will commit to promoting equity, diversity, and inclusion in the data science research environment and provide training opportunities for minority and underrepresented communities. Finally, our Administrative Core will facilitate the annual Scientific Review of progress on the research, training, and outreach goals of the Stanford CCSB by our External Advisory Board and the National Cancer Institute.