Administrative Core

行政核心

• 批准号: 10729465
• 负责人: SYLVIA KATINA PLEVRITIS
• 金额: $ 36.05万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-19 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10729465
• 关键词: Address; Administrator; Award; Cancer Biology; Cancer Center; Collaborations; Communication; Communities; Complex; Computational Science; Conflict of Interest; Consensus; Data; Data Science; Data Set; Effectiveness; Engineering; Ensure; Environment; Equity; Evaluation; Fostering; Funding; Future; Generations; Goals; Guidelines; Immune; Institution; Interdisciplinary Study; Justice; Learning; Life Experience; Malignant Neoplasms; Minority; Monitor; National Cancer Advisory Board; National Cancer Institute; Occupational activity of managing finances; Office of Administrative Management; Performance; Pilot Projects; Process; Productivity; Recommendation; Reporting; Research; Research Personnel; Resource Sharing; Resources; Services; Site; Systems Biology; Training; Tumor Biology; United States National Institutes of Health; Universities; Voting; Work; anticancer research; community engagement; data access; data centers; data management; design; diversity and inclusion; equity, diversity, and inclusion; experience; innovation; member; molecular oncology; multidisciplinary; operation; organizational structure; outreach; programs; statistics; tool; training opportunity; tumor

ABSTRACT/SUMMARY: Administrative Core The Administrative Core of our proposed Stanford Center for Cancer Systems Biology (CCSB) will provide the logistical support for all coordinated activities related to our Center. It will operate under an organizational structure that facilitates communication and access across all components of our Research Center, other NIH CSBC Research Centers, the NIH CSBC Program staff, and the proposed U24 Coordinating Center. Internally, our CCSB will have an Executive Committee, Steering Committee, and Internal Advisory Board (IAB) to oversee the scientific, training, and outreach activities of our Center and ensure that our overall goals and specific aims are being met. Our Executive Committee will be led by our MPIs, who have successfully led our CCSB program over the past five years, along with the support of our Center Data Manager, who will oversee the coordination of the Biospecimen and Data Core and ensure overall management of data generation and pre- and post- processing and sharing, and our Center Administrator, who will monitor and execute daily administrative center operations. Our Steering Committee will be composed of the Core Leads and co-Leads, Project Leads and co- Leads, and the Data Center Manager. The IAB will be available to provide our Center with scientific advice, general evaluation, and address specific issues related to our annual site review. Additionally, we will establish an External Advisory Board (EAB) of key advisors to benefit from their extensive experience relevant to complex systems biology issues related to tumor-immune-stromal interactions in metastatic progression. In order to expand our network of investigators, our Administrative Core will facilitate our proposed Intra-center Pilot Project in Years 1-5 and Cross-Consortium Project in Years 2-5 of the program. Our Administrative Core will coordinate the solicitation, application and review processes. These pilot projects will be evaluated and awarded based on scientific merit with the aim of fostering new avenues of research aligned with the scientific theme of our Research Center. The cross-consortium projects will be funded to increase research opportunities for collaborative and interactive efforts among members of the consortium. The Administrative Core will commit to promoting equity, diversity, and inclusion in the data science research environment and provide training opportunities for minority and underrepresented communities. Finally, our Administrative Core will facilitate the annual Scientific Review of progress on the research, training, and outreach goals of the Stanford CCSB by our External Advisory Board and the National Cancer Institute.

摘要/摘要：行政核心 我们拟议的斯坦福大学癌症系统生物学中心（CCSB）的行政核心将提供 对与我们中心有关的所有协调活动的后勤支持。它将在组织下运作 促进研究中心所有组成部分的沟通和访问的结构，其他NIH CSBC研究中心，NIH CSBC计划人员和拟议的U24协调中心。在内部 我们的CCSB将有一个执行委员会，指导委员会和内部咨询委员会（IAB）来监督 我们中心的科学，培训和外展活动，并确保我们的整体目标和特定目标 被满足。我们的执行委员会将由我们的MPI领导，他们成功地领导了我们的CCSB计划 在过去的五年中，在我们的中心数据经理的支持下，他们将监督协调 生物测量和数据核心的核心，并确保数据生成以及前后的总体管理 处理和共享，以及我们的中心管理员，他们将监视和执行每日管理中心 运营。我们的指导委员会将由核心线索和共同领导，项目主角和共同领导组成 线索和数据中心经理。 IAB将可以为我们的中心提供科学建议， 一般评估，并解决与我们的年度现场审查有关的特定问题。此外，我们将建立 主要顾问的外部顾问委员会（EAB），旨在从与复杂有关的丰富经验中受益 系统生物学问题与转移性进展中的肿瘤 - 免疫 - 层相互作用有关。为了 扩展我们的调查人员网络，我们的行政核心将促进我们拟议的中心试点项目 在该计划2 - 5年的1 - 5年和跨境项目中。我们的行政核心将协调 招标，应用和审查过程。这些试点项目将根据 科学优点的目的是促进与我们的科学主题保持一致的新的研究途径 研究中心。跨境项目将资助以增加研究机会 财团成员之间的协作和互动式努力。行政核心将承诺 促进公平，多样性和在数据科学研究环境中的包容性，并提供培训 少数民族和代表性不足的社区的机会。最后，我们的行政核心将促进 我们的研究，培训和外展目标进展的年度科学评论，我们的斯坦福CCSB 外部顾问委员会和国家癌症研究所。