Massachusetts Center for Alzheimer and dEmeNtia behaVIoral reSearch In minOrity agiNg (Mass-ENVISION)

马萨诸塞州老年痴呆症和痴呆症研究中心是一个 建议新的阿尔茨海默氏症相关资源中心的少数民族老龄化研究（AD/ADRD RCMAR），将解决 迫切需要为医学界代表性不足的科学家提供指导性研究培训， 测试，并在医院和社区环境中实施行为干预， 患有阿尔茨海默病和相关疾病（ADRD）的少数老年人及其非正式护理伙伴。有一个 缺乏基于证据的行为干预措施，以支持少数老年人与ADRD，他们的非正式护理 合作伙伴和二人组，以及准备缓解这一短缺的UiM科学家数量方面的严重缺口。解决 这些研究和资源的差距，马萨诸塞州将确定UiM科学家谁是致力于ADRD行为 卫生和干预研究，并将支持培训和发展独立的UiM科学家准备， 消除ADRD行为健康方面的健康差异和不公平。此外，大规模扩张将成为唯一的 RCMAR为整个新英格兰地区服务，该地区急需这种资源。大规模扩展，一个合作 马萨诸塞州总医院（MGH）、波士顿大学（BU）和剑桥健康联盟及其医疗 学校附属机构（哈佛医学院，BU医学院），大学附属医院，其他波士顿和MA- 地区研究中心，卫星医院和社区诊所，将提供RCMAR科学家跨学科， 在ADRD行为健康和干预研究中进行全面的培训和持续的量身定制的指导， 修订后的NIH阶段模型，行为改变科学，疾病控制中心的预防方法 基于疾病阶段（即，小学、中学、大学）和国家医学院基于目标的（指示， 选择性的，普遍的）框架和NIA健康差异研究框架。大规模扩张将合作 与其他NIA资助的中心及其研究人员密切合作，包括马萨诸塞州阿尔茨海默病研究中心 中心（MADRC），波士顿大学ADRC（BU-ADRC）和波士顿克劳德D。胡椒老年美国人独立 中心，将生物学和流行病学的进展转化为ADRD行为干预的机制目标。 大规模扩展将由UiM PI领导，Okereke博士（MGH老年精神病学和MGH精神病学中心主任） 种族平等和正义），与团队成员和核心领导/共同领导有着良好的合作记录， 也来自不同的UiM背景（例如，黑人，亚洲人，拉丁美洲人，第一代大学生），并有互补性 ADRD，健康差异和健康公平研究，社会和行为健康，行为干预， 实施科学和跨学科科学。大规模扩展将有4个核心：领导和行政， 研究教育部分，数据和分析，社区联络和招聘。核心将由 研究人员在背景、MA和大波士顿的机构隶属关系、学科、 以及研究和培训技能，以促进Mass-Exposition在发展包容性研究指导方面取得成功 环境和多样化的生物医学研究队伍，以促进ADRD行为健康的健康公平。

Massachusetts Center for Alzheimer and dEmeNtia behaVIoral reSearch In minOrity agiNg (Mass-ENVISION) is a proposed new Alzheimer's-related Resource Centers for Minority Aging Research (AD/ADRD RCMAR) that will address the critical need for mentored research training for underrepresented in medicine (UiM) scientists in the development, testing, and implementation of behavioral interventions across hospital and community settings, for racial and ethnic minority older adults with Alzheimer’s Disease and Related Disorders (ADRD) and their informal care partners. There is a dearth of evidence-based behavioral interventions to support minority older persons with ADRD, their informal care partners, and dyads, as well as a critical gap in the number of UiM scientists poised to mitigate this shortage. To address these research and resource gaps, Mass-ENVISION will identify UiM scientists who are committed to ADRD behavioral health and interventions research and will support training and development of independent UiM scientists poised to eliminate health disparities and inequities in ADRD behavioral health. Further, Mass-ENVISION would become the only RCMAR to serve the entire New England region, which is in critical need of this resource. Mass-ENVISION, a collaboration of Massachusetts General Hospital (MGH), Boston University (BU) and Cambridge Health Alliance and their medical school affiliations (Harvard Medical School, BU School of Medicine), university-affiliated hospitals, other Boston and MA- area research centers, satellite hospitals and community clinics, will provide RCMAR Scientists with interdisciplinary, comprehensive training and sustained and tailored mentoring in ADRD behavioral health and interventions research using the revised NIH Stage Model, the Science of Behavior Change, prevention approaches under the Centers for Disease Control disease stage-based (i.e., primary, secondary, tertiary) and the National Academy of Medicine target-based (indicated, selective, universal) frameworks, and the NIA Health Disparities Research Framework. Mass-ENVISION will collaborate closely with other NIA-funded Centers and their investigators, including the Massachusetts Alzheimer’s Disease Research Center (MADRC), Boston University ADRC (BU-ADRC) and Boston Claude D. Pepper Older Americans Independence Center, to translate biological and epidemiological advances as mechanistic targets for ADRD behavioral interventions. Mass-ENVISION will be led by a UiM PI, Dr. Okereke (Director, MGH Geriatric Psychiatry and MGH Psychiatry Center for Racial Equity and Justice), with strong collaborative track records with team members and Core Leads/Co-Leads, who are also from diverse and UiM backgrounds (e.g., Black, Asian, Latino, first generation at college) and have complementary expertise in ADRD, health disparities and health equity research, social and behavioral health, behavioral interventions, implementation science, and interdisciplinary science. Mass-ENVISION will have 4 Cores: Leadership and Administrative, Research Education Component, Data and Analysis, and Community Liaison and Recruitment. Cores will be composed of investigators who are diverse with respect to backgrounds, institutional affiliations in MA and Greater Boston, disciplines, and research and training skills, to facilitate Mass-ENVISION’s success in developing an inclusive research mentoring environment and a diverse biomedical research workforce to advance health equity in ADRD behavioral health.