Leadership and Administrative Core (LAC)

领导和行政核心 (LAC)

• 批准号: 10729790
• 负责人: Olivia Ifeoma Okereke
• 金额: $ 24.16万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10729790
• 关键词: Academy; Achievement; Advocate; Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; Behavior Therapy; Behavioral Research; Benchmarking; Biomedical Research; Boston; Caring; Centers for Disease Control and Prevention (U.S.); Collaborations; Communities; Community Participation; Data; Dementia; Development; Elderly; Ensure; Evaluation; Funding; General Hospitals; Goals; Hospitals; Infrastructure; Institution; Intervention; Intervention Studies; Investigation; Knowledge; Lead; Leadership; Massachusetts; Medicine; Mentors; Methodology; Minority; Minority Health Research; Mission; Modeling; Monitor; New England; Patients; Performance; Persons; Pilot Projects; Prevention; Process; Reporting; Research; Research Personnel; Research Project Grants; Resources; Risk Behaviors; Science; Scientist; Supervision; System; Testing; Training; Training Support; Training and Infrastructure; United States National Institutes of Health; Universities; Work; anti-racism; behavior change; behavioral health; behavioral health intervention; career; career development; community center; community engaged research; community engagement; community setting; digital; education research; empowerment; equity, diversity, and inclusion; experience; functional improvement; health disparity; informal care; member; next generation; novel; programs; recruit; skills; success

The goal of the Leadership and Administrative Core (LAC) is to provide the overall infrastructure and scientific and intellectual leadership of the translational, interdisciplinary, collaborative, and investigator development functions that are expected of an AD/ADRD RCMAR. The Scientific Theme of Mass-ENVISION (Massachusetts Center for Alzheimer and dEmeNtia behaVIoral reSearch In minOrity agiNg) is the training and sustained and tailored mentoring of underrepresented in medicine (UiM) scientists in developing, testing and implementing of scientifically rigorous behavioral health interventions for persons with ADRD (Alzheimer disease and related dementias) and their informal care partners in hospital and community settings. The rationale for selecting this scientific theme is the critical need for new ADRD behavioral interventions as well as the need to diversify biomedical research, consistent with the call for ADRD behavioral research under RFA-AG-23-025. All RCMAR Scientists will receive training in ADRD behavioral health and interventions research anchored to the newly revised (2022) NIH Stage Model, the Science of Behavior Change, the NIA Health Disparities Framework and the CDC (Centers for Disease Control) and NAM (National Academy of Medicine) prevention models. The LAC will conduct its work through 3 Specific Aims. Aim 1. Establish the leadership, infrastructure and community to support the Mass-ENVISION Scientific Theme. The LAC will: Provide administrative leadership, oversight and facilitation of scientific interactions and collaborations across all Cores and component institutions, as well as with other regional NIA Centers, including 2 Alzheimer’s Disease Research Centers (ADRCs); Ensure that principles and practices of diversity, equity, inclusion, accessibility and anti-racism are integrated throughout all Cores and RCMAR Scientists’ training experiences; Promote a community-centered focus to the work conducted by all Cores. Aim 2. Support rigorous training and career development for RCMAR Scientists in the Mass-ENVISION Scientific Theme. The LAC will: Coordinate with the Research Education Component and Data and Analysis Core teams to support training of RCMAR Scientists in knowledge and methodologically rigorous application of novel ADRD behavioral health and interventions. Aim 3. Evaluate success of the RCMAR and of RCMAR Scientists. The LAC will: Create systems, resources and processes for monitoring of mentoring success and progress of RCMAR Scientists and pilot studies; Monitor, record and report performance metrics of this RCMAR and support dissemination of successful systems, resources and processes to other RCMARs, ADRCs and the scientific community. The LAC team will consist of PI Dr. Okereke, Associate Director Dr. Budson, a Program Manager, and LAC members Drs. Blacker, Gomez-Isla, Hyman and Keuroghlian; it includes senior leadership members of both the Massachusetts ADRC and Boston University ADRC. The LAC features high levels of leadership, administrative experience, and complementary skills to oversee and facilitate effective and impactful interactions and collaborations across all Cores, partnering institutions, stakeholders, and programs, to support the achievement of all Aims of Mass-ENVISION.

领导和行政核心的目标是提供全面的基础设施和科学， 翻译，跨学科，协作和研究者发展职能的智力领导， AD/ADRD RCMAR的预期。大规模痴呆的科学主题（马萨诸塞州阿尔茨海默病中心和 dEmentia少数群体研究）是对代表性不足的人进行培训和持续的、有针对性的指导， 医学（UiM）科学家在开发，测试和实施科学严谨的行为健康 对ADRD（阿尔茨海默病和相关痴呆症）患者及其住院非正式护理伙伴的干预措施 和社区设置。选择这一科学主题的理由是迫切需要新的ADRD行为 干预措施以及多样化生物医学研究的必要性，与ADRD行为研究的要求一致 根据RFA-AG-23-025。所有RCMAR科学家将接受ADRD行为健康和干预研究的培训 锚定到新修订的（2022）NIH阶段模型，行为改变的科学，NIA健康差异 框架和CDC（疾病控制中心）和NAM（国家医学科学院）预防模式。的 法律援助委员会将通过三个具体目标开展工作。目标1。建立领导层、基础设施和社区， 支持大众科学主题。提供行政领导、监督和便利 所有核心和组成机构之间以及与其他区域国家影响评估之间的科学互动与合作 中心，包括2个阿尔茨海默病研究中心（ADRC）;确保多样性的原则和做法， 公平、包容、无障碍和反种族主义被纳入所有核心和RCMAR科学家的培训 促进以社区为中心的重点，以所有核心进行的工作。目标二。支持严格的培训 和职业发展的RCMAR科学家在大规模扩展科学主题。法律援助委员会将： 研究教育部分和数据与分析核心团队，以支持RCMAR科学家的培训， 新ADRD行为健康和干预措施的知识和方法学上的严格应用。目标3.评价 RCMAR和RCMAR科学家的成功。建立监测系统、资源和程序 指导RCMAR科学家和试点研究的成功和进展;监控，记录和报告绩效指标 支持将成功的系统、资源和流程传播给其他区域合作监测和评估报告、发展成果中心， 科学界。LAC团队将由PI博士Okereke，副主任博士Budson，项目经理， 和LAC成员布莱克博士，戈麦斯-伊斯拉，海曼和Keuroghlian;它包括高级领导成员， 马萨诸塞州ADRC和波士顿大学ADRC。LAC具有高水平的领导能力，行政经验， 和互补技能，以监督和促进所有核心之间有效和有影响力的互动和协作， 与机构、利益相关者和方案结成伙伴关系，以支持实现大规模宣传的所有目标。