Facility Management, Maintenance and Operation Core

设施管理、维护和运营核心

• 批准号: 10793828
• 负责人: Mark D Richardson
• 金额: $ 88.24万
• 依托单位: UNIVERSITY OF MISSOURI-COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-18 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10793828
• 关键词: Advanced Development; Affect; Agreement; Animal Housing; Animals; Area; Arthropods; Award; Carbon Dioxide; Chills; Communicable Diseases; Communication; Communities; Containment; Contractor; Decontamination; Dedications; Disease; Diverse Workforce; Educational process of instructing; Emergency Situation; Emerging Communicable Diseases; Ensure; Environment; Equipment; Event; Floor; Funding; Goals; Human Resources; Individual; Infectious Diseases Research; Infrastructure; Investments; Laboratories; Leadership; Maintenance; Missouri; Modeling; Names; National Institute of Allergy and Infectious Disease; Natural Gas; Periodicals; Power Sources; Preventive; Preventive service; Procedures; Property; Research; Research Priority; Research Support; Resource Development; Resource Sharing; Resources; Risk; Safety; Schedule; Science; Secure; Security; Services; Side; Site; Steam; System; Testing; Training; United States National Institutes of Health; Universities; Veterinary Medicine; Viral; Water; Water Purification; Work; Workforce Development; Zoonoses; base; biocontainment facility; biodefense; biosafety level 3 facility; biosecurity; design; falls; high efficiency particulate air filter; improved; medical countermeasure; meetings; novel; operation; pandemic disease; pandemic preparedness; pandemic response; pathogen; pathogenic bacteria; pathogenic virus; priority pathogen; programs; recruit; repaired; research and development; research facility; response; skills; synergism; vector-borne; water treatment

Project Summary Core 1: Facilities Management, Maintenance, and Operations Core The University of Missouri Regional Biocontainment Laboratory, the Laboratory for Infectious Disease Research (LIDR) is a stand-alone facility, located in the east side of campus, that was designed to support research on select agent pathogens requiring biosafety level 3 (BSL-3) containment. Because of the safety and security risks associated with this research program, the LIDR follows strict site and building security procedures as well as a rigorous and comprehensive building maintenance schedule and strong personnel infrastructure to maintain continuous operations of the biocontainment facility. The Facilities Management, Maintenance, and Operations Core (Core 1 of this UC7 application) is responsible for site and building security and proper functioning of all building systems. Operations and management of the BSL-3 containment areas involves dozens of trades, needing HVAC, telecom, steam, hot-water boilers, campus steam, chilled water, electrical distribution, natural gas, emergency generator, CO2 distribution, water treatment and purification, effluent decontamination, and an on-site chiller for back-up chilled water. Together the building systems in conjunction with tested emergency procedures provide redundancy for all off-normal events that could impact the containment areas and adversely affect research, laboratory workers, and/or the environment. The breadth of expertise needed to maintain building systems is provided by the MU Campus Facilities group, who employs tradesman in every area that are assigned to preventive maintenance and repair duties. In addition, there are presently 57 select agent-approved individuals, along with daily and periodic visitors including building maintenance contractors, renovation contractors, skilled tradespeople, custodial staff, facility and program inspectors, and users from the broader infectious disease community at MU. As LIDR BSL-3 laboratories are approved for select agent research, the site security and biosafety plans require a significant workforce dedicated to facilities management. The objectives of the proposed Facilities Management, Maintenance, and Operations Core are to increase efficiencies of the BSL-3/ACL-3/ABSL-3 research program at LIDR, to train an outstanding biocontainment facilities workforce, and contribute to the RBL-NBL network by sharing of resources and best practices in the management of high containment facilities. To achieve these goals, the proposed core will work closely with the BSL-3 Practices Core (core 2) and the Biocontainment Services and Research Resources Core (core 3) to provide synergy in meeting the needs of the BSL-3 and broader research communities in order to advance the development of novel medical countermeasures against high consequence bacterial and viral priority pathogens.

项目概要 核心 1：设施管理、维护和运营核心 密苏里大学区域生物防护实验室、传染病研究实验室 （LIDR）是一个独立的设施，位于校园东侧，旨在支持以下方面的研究 选择需要生物安全 3 级 (BSL-3) 遏制的病原体。由于存在安全和治安风险 与该研究项目相关，LIDR 遵循严格的场地和建筑安全程序以及 严格而全面的建筑维护计划和强大的维护人员基础设施 生物防护设施的持续运行。设施管理、维护和运营 核心（此 UC7 应用程序的核心 1）负责站点和建筑安全以及所有功能的正常运行 建筑系统。 BSL-3收容区的运营和管理涉及数十个行业， 需要暖通空调、电信、蒸汽、热水锅炉、校园蒸汽、冷冻水、配电、自然 燃气、应急发电机、二氧化碳分配、水处理和净化、污水净化和 用于备用冷冻水的现场冷水机。将建筑系统与经过测试的紧急情况结合在一起 程序为所有可能影响收容区域并产生不利影响的非正常事件提供冗余 影响研究、实验室工作人员和/或环境。维护所需的专业知识的广度 建筑系统由密西根大学校园设施小组提供，该小组在每个区域都雇用了技工 分配预防性维护和维修职责。此外，目前还有 57 个精选代理商批准的 个人以及日常和定期访客，包括建筑维护承包商、装修承包商 承包商、熟练技工、保管人员、设施和项目检查员以及更广泛的用户 密苏里大学传染病社区。由于 LIDR BSL-3 实验室已获准进行精选药物研究，因此 场地安全和生物安全计划需要大量致力于设施管理的劳动力。这 拟议的设施管理、维护和运营核心的目标是增加 LIDR 的 BSL-3/ACL-3/ABSL-3 研究计划的效率，以培养杰出的生物防护 设施员工队伍，并通过共享资源和最佳实践为 RBL-NBL 网络做出贡献 高密闭设施的管理。为了实现这些目标，拟议的核心将与 BSL-3 实践核心（核心 2）和生物防护服务和研究资源核心（核心 3） 提供协同作用以满足 BSL-3 和更广泛的研究界的需求，以推进 开发针对高后果细菌和病毒优先病原体的新型医疗对策。