Facility Management, Maintenance and Operation Core

设施管理、维护和运营核心

• 批准号: 10793828
• 负责人: Mark D Richardson
• 金额: $ 88.24万
• 依托单位: UNIVERSITY OF MISSOURI-COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-18 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10793828
• 关键词: Advanced Development; Affect; Agreement; Animal Housing; Animals; Area; Arthropods; Award; Carbon Dioxide; Chills; Communicable Diseases; Communication; Communities; Containment; Contractor; Decontamination; Dedications; Disease; Diverse Workforce; Educational process of instructing; Emergency Situation; Emerging Communicable Diseases; Ensure; Environment; Equipment; Event; Floor; Funding; Goals; Human Resources; Individual; Infectious Diseases Research; Infrastructure; Investments; Laboratories; Leadership; Maintenance; Missouri; Modeling; Names; National Institute of Allergy and Infectious Disease; Natural Gas; Periodicals; Power Sources; Preventive; Preventive service; Procedures; Property; Research; Research Priority; Research Support; Resource Development; Resource Sharing; Resources; Risk; Safety; Schedule; Science; Secure; Security; Services; Side; Site; Steam; System; Testing; Training; United States National Institutes of Health; Universities; Veterinary Medicine; Viral; Water; Water Purification; Work; Workforce Development; Zoonoses; base; biocontainment facility; biodefense; biosafety level 3 facility; biosecurity; design; falls; high efficiency particulate air filter; improved; medical countermeasure; meetings; novel; operation; pandemic disease; pandemic preparedness; pandemic response; pathogen; pathogenic bacteria; pathogenic virus; priority pathogen; programs; recruit; repaired; research and development; research facility; response; skills; synergism; vector-borne; water treatment

Project Summary Core 1: Facilities Management, Maintenance, and Operations Core The University of Missouri Regional Biocontainment Laboratory, the Laboratory for Infectious Disease Research (LIDR) is a stand-alone facility, located in the east side of campus, that was designed to support research on select agent pathogens requiring biosafety level 3 (BSL-3) containment. Because of the safety and security risks associated with this research program, the LIDR follows strict site and building security procedures as well as a rigorous and comprehensive building maintenance schedule and strong personnel infrastructure to maintain continuous operations of the biocontainment facility. The Facilities Management, Maintenance, and Operations Core (Core 1 of this UC7 application) is responsible for site and building security and proper functioning of all building systems. Operations and management of the BSL-3 containment areas involves dozens of trades, needing HVAC, telecom, steam, hot-water boilers, campus steam, chilled water, electrical distribution, natural gas, emergency generator, CO2 distribution, water treatment and purification, effluent decontamination, and an on-site chiller for back-up chilled water. Together the building systems in conjunction with tested emergency procedures provide redundancy for all off-normal events that could impact the containment areas and adversely affect research, laboratory workers, and/or the environment. The breadth of expertise needed to maintain building systems is provided by the MU Campus Facilities group, who employs tradesman in every area that are assigned to preventive maintenance and repair duties. In addition, there are presently 57 select agent-approved individuals, along with daily and periodic visitors including building maintenance contractors, renovation contractors, skilled tradespeople, custodial staff, facility and program inspectors, and users from the broader infectious disease community at MU. As LIDR BSL-3 laboratories are approved for select agent research, the site security and biosafety plans require a significant workforce dedicated to facilities management. The objectives of the proposed Facilities Management, Maintenance, and Operations Core are to increase efficiencies of the BSL-3/ACL-3/ABSL-3 research program at LIDR, to train an outstanding biocontainment facilities workforce, and contribute to the RBL-NBL network by sharing of resources and best practices in the management of high containment facilities. To achieve these goals, the proposed core will work closely with the BSL-3 Practices Core (core 2) and the Biocontainment Services and Research Resources Core (core 3) to provide synergy in meeting the needs of the BSL-3 and broader research communities in order to advance the development of novel medical countermeasures against high consequence bacterial and viral priority pathogens.

项目摘要 核心1：设施管理，维护和操作核心 密苏里大学区域生物内在实验室，传染病研究实验室 （LIDR）是位于校园东侧的独立设施，旨在支持研究 需要生物安全3（BSL-3）遏制的选择试剂病原体。由于安全和保障风险 与该研究计划相关联，LIDR遵循严格的站点和建筑安全程序以及 严格而全面的建筑维护时间表和强大的人员基础设施以维护 生物维护设施的连续运营。设施管理，维护和运营 核心（本uc7应用程序的核心1）负责站点和建立安全性和所有所有人的正确功能 建筑系统。 BSL-3遏制区域的运营和管理涉及数十项交易， 需要HVAC，电信，蒸汽，热水锅炉，校园蒸汽，冰冷的水，电源，天然 天然气，应急发电机，二氧化碳分布，水处理和纯化，废水去污和 现场冷却器，用于备用冷水。建筑系统与经过测试的紧急情况结合在一起 程序为所有可能影响遏制区域和不利的正常事件提供了冗余 影响研究，实验室工人和/或环境。维护所需的专业知识广度 建筑系统由MU校园设施小组提供，他们在每个地区雇用商人 分配给预防性维护和维修职责。此外，目前还有57个选择代理商批准 个人，以及包括建筑维护承包商在内的日常和周期性访客，翻新 承包商，熟练的商人，托管人员，设施和计划检查员以及更广泛的用户 MU的传染病社区。由于LIDR BSL-3实验室被批准用于精选代理研究，因此 站点安全和生物安全计划需要致力于设施管理的重要劳动力。这 拟议的设施管理，维护和操作核心的目标是增加 LIDR的BSL-3/ACL-3/ABSL-3研究计划的效率 设施劳动力，并通过共享资源和最佳实践来为RBL-NBL网络做出贡献 管理高遏制设施的管理。为了实现这些目标，提议的核心将与 BSL-3实践核心（核心2）和生物内在维护服务和研究资源核心（核心3） 为满足BSL-3和更广泛的研究社区的需求提供协同作用，以促进 开发新的医学对策，反对高后果的细菌和病毒优先病原体。