BSL-3 Practices Core

BSL-3 实践核心

• 批准号: 10793950
• 负责人: JOSEPH A. KANABROCKI
• 金额: $ 60.4万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-18 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10793950
• 关键词: Address; Animals; Area; Attention; Awareness; Biocompatible Materials; Biological; Biological Products; Biomedical Research; Categories; Chicago; Communicable Diseases; Communication Tools; Communities; Competence; Containment of Biohazards; Coordination and Collaboration; Dangerousness; Decontamination; Development; Discipline; Disease; Education; Educational Curriculum; Elements; Emergency response; Emerging Communicable Diseases; Engineering; Ensure; Environment; Equipment; Equipment and supply inventories; Family; Goals; Human; Human Resources; Individual; Infectious Diseases Research; Infrastructure; Laboratories; Laboratory Research; Maintenance; Mentors; Mission; National Institute of Allergy and Infectious Disease; Pathogenicity; Procedures; Program Description; Property; Recommendation; Research; Research Personnel; Resources; Risk; Risk Assessment; Safety; Scientist; Secure; Services; System; Toxin; Training; Training Programs; Training and Education; United States; Universities; Update; Work; biocontainment facility; biodefense; biosecurity; design; experience; hazard; investigator training; meetings; member; microorganism; operation; pathogen; personal protective equipment; programs; skills; synergism

PROJECT ABSTRACT (Core 2/C2BSL3@HTRL) The University of Chicago Howard T. Ricketts Biocontainment Laboratory is proposing the establishment of a A/BSL-3 Practices Core, C2BSL3@HTRL, to provide comprehensive training and mentoring in the safe use of pathogenic microorganisms, toxins, and Select Agents. The curriculum covers topics such as biosecurity, risk assessment, biohazard containment, safe handling of pathogens, decontamination, and emergency response plans. The core will develop and maintain Standard Operating Procedures (SOPs) and provide training for personnel working in the A/BSL-3 space and associated building systems. This core will employ an integrated approach to Biosafety education by strategically coordinating and synergizing the educational experiences for research investigators and support staff, Biosafety professionals, and biocontainment facility engineers. Elements of the training provided by C2BSL3@HTRL include the following:  Annual HTRL Training: This training covers all aspects of biosafety, including the properties of biological agents, risk assessment, personal protective equipment, decontamination, and emergency response plans and is given to all members of the HTRL team.  HTRL Hands-On (one-on-one) Training and Mentoring: This one-on-one training program ensures everyone receives personalized attention and training to address their specific needs, skills, and competencies to work successfully and safely in A/BSL3.  HTRL Monthly Training: The monthly training serves as a vital communication tool for updating all facility users on various aspects of the laboratory. The meeting provides training on future research areas and addresses any concerns or questions that users may have, which promotes collaboration and coordination among all HTRL users.  Aerobiology Maintenance and Training: The aerobiology core provides training on the unique challenges, design, setup, and safe practices of aerobiology and use of the Class III Biosafety Cabinet.  Development of Select Agent SOPs and Inventory: This program describes the development of SOPs and training on inventory reconciliation for all Select Agents and RG3 pathogens.

项目摘要(Core 2/C2BSL3@HTRL) 芝加哥大学霍华德·T·里基茨生物遏制实验室提议建立一个 A/BSL-3实践核心，C2BSL3@HTRL，提供安全使用方面的全面培训和指导 病原微生物、毒素和选择剂。课程包括生物安全、风险等主题。 评估、生物危害控制、病原体安全处理、净化和应急响应 计划。核心将制定和维护标准操作程序(SOP)，并为 在A/BSL-3空间和相关建筑系统工作的人员。该核心将采用集成的 从战略上协调和协同生物安全教育的经验 研究人员和支持人员、生物安全专业人员和生物遏制设施工程师。 C2BSL3@HTRL提供的培训内容包括： 年度HTRL培训：此培训涵盖生物安全的方方面面，包括 生物制剂、风险评估、个人防护装备、去污和紧急情况 响应计划，并提供给HTRL团队的所有成员。 HTRL实践(一对一)培训和指导：这一一对一培训计划确保 每个人都接受个性化的关注和培训，以满足他们的特定需求、技能和 在A/BSL3中成功和安全地工作的能力。 HTRL每月培训：每月培训是更新所有 在实验室的各个方面为用户提供便利。会议提供了关于未来研究领域的培训 并解决用户可能存在的任何担忧或问题，从而促进协作和 协调所有HTRL用户。 航空生物学维护和培训：航空生物学核心提供独特的 空气生物学的挑战、设计、设置和安全实践以及三级生物安全柜的使用。 选择代理SOP和库存的开发：本程序描述SOP的开发 以及针对所有精选试剂和RG3病原体的库存核对培训。