Latinx Hazardous Drinkers: Evaluating Microaggressions

项目摘要/摘要 这是一份以患者为导向的导师研究职业发展奖(K23)的申请书，以支持 申请人的学术生涯发展情况。候选人的长期目标是成为一名 在理论理解、治疗和干预方面的独立临床研究人员和领导者 拉丁裔人群中的危险饮酒和焦虑。申请人曾就以下事项进行研究 跨诊断过程(主要是焦虑敏感)及其与健康行为研究的关系 (主要集中在吸烟)在非拉丁裔白人个人中。最近，申请者已经 从事研究，重点是拉丁裔个人的酒精使用以及与以下方面相关的少数民族压力 拉丁裔人群中的吸烟行为。因此，申请人建议在过去和最近的基础上再接再厉 研究经验，以及她在心理健康方面的临床培训，遵循了一种合乎逻辑但新颖的， 从先前的研究和培训经验发展到发展一个新的专门领域 拉丁裔人群中可能受影响的酒精和焦虑相关过程的设计和评估 由少数族裔相关的压力源造成。导师将由一组模范高级调查人员提供，并将 促进候选人在这一新研究领域的发展。申请人提出了一项全面的 培训计划，包括五个方面的发展：(1)与以下方面有关的理论和经验知识 拉丁裔成年人中危险饮酒和焦虑背景下的少数民族压力模型，(2)高级 通过生态瞬间评估(EMA)的纵向研究设计，(3)经验回避 (EA)作为跨诊断机制，(4)高级分析培训，和(5)高级研究技能 研究传播、领导力和资质。通过这一资助机制，候选人的 拟议的研究旨在：(1)考察微攻击(MA)的影响--日常生活中简短、微妙的形式 基于种族/民族地位的歧视--关于饮酒动机和危险饮酒，(2)审查 MAS对焦虑体验的影响；(3)通过评估来探索这些关系的机制 MA通过电针对酒精和焦虑相关过程的间接影响，以及(4)探索 与酒精和焦虑有关的过程，包括特定于文化的结构(例如，种族认同、亲密度、 200名拉丁裔成年人的文化适应压力，他们是危险饮酒者。此外，我们试图澄清是否 MA有别于非歧视性的日常应激源和公开的种族主义，对 建议的结果。这一提议被概念化为翻译研究的典型范例 可以从多方法框架中解释机制，以增强我们对复杂少数群体的理解 压力和危险饮酒与焦虑的关系，并成为这一新兴领域未来工作的催化剂 在健康不平等群体中的一个领域。从这项建议中获得的知识和经验将使 应聘者拥有一套独特的技能，能够在这一重要但未被充分研究的领域提升知识。

PROJECT SUMMARY/ABSTRACT This is an application for a Mentored Patient-Oriented Research Career Development Award (K23) to support the academic career development of the applicant. The candidate's long-term goal is to become an independent clinical investigator and leader in the theoretical understanding, treatment, and intervention of hazardous drinking and anxiety among Latinx persons. The applicant has conducted research on transdiagnostic processes (predominantly anxiety sensitivity) and their association to health behavior research (predominately focused on smoking) among non-Latinx White individuals. More recently, the applicant has engaged in research focused on alcohol use among Latinx individuals as well as minority stress as it relates to smoking behaviors among Latinx persons. Thus, the applicant proposes to build on her past and more recent research experience, as well as her clinical training, in mental health and follows a logical, but novel, progression from prior research and training experiences to development of a new area of expertise in the design and evaluation of alcohol- and anxiety-related processes among Latinx persons who may be impacted by minority-related stressors. Mentorship will be provided by a group of exemplar senior investigators and will foster the candidate's development in this new area of research. The applicant proposes a comprehensive training plan that includes development in five areas: (1) theoretical and empirical knowledge relevant to minority stress models in the context of hazardous drinking and anxiety among Latinx adults, (2) advanced longitudinal research design through Ecological Momentary Assessments (EMA), (3) experiential avoidance (EA) as a transdiagnostic mechanism, (4) advanced analytic training, and (5) advanced research skills in research dissemination, leadership, and grantsmanship. Through this funding mechanism, the candidate’s proposed study aims to: (1) examine the influence of microaggressions (MAs) – brief, subtle forms of everyday discrimination due to racial/ethnic status – on alcohol use motivation and hazardous drinking, (2) examine the influence of MAs on anxiety experience, (3) explore the mechanisms underlying these relations by evaluating the indirect effects of MAs on alcohol- and anxiety-related processes via EA, and (4) explore moderators of alcohol- and anxiety-related processes, including cultural-specific constructs (e.g., ethnic identity, familisimo, acculturative stress among 200 Latinx adults who are hazardous drinkers. Moreover, we seek to elucidate if MAs are distinct from, and more impactful than, non-discriminatory daily stressors and overt racism on the proposed outcomes. This proposal is conceptualized as a prototypical example of translational research that can explicate mechanisms from a multi-method framework to enhance our understanding of complex minority stress and hazardous drinking and anxiety relations and serve as a catalyst for future work in this emerging domain among a health disparities group. The knowledge and experience gained from this proposal will equip the candidate with a unique set of skills to advance knowledge in this important but understudied area.