Latinx Hazardous Drinkers: Evaluating Microaggressions

项目概要/摘要 这是一个指导病人为导向的研究职业发展奖（K23）的应用程序，以支持 申请人的学术生涯发展。候选人的长期目标是成为一名 独立的临床研究者和领导者在理论上的理解，治疗和干预， 危险的饮酒和拉丁人的焦虑。申请人进行了研究， 转诊断过程（主要是焦虑敏感性）及其与健康行为研究的关联 （主要集中在吸烟）在非拉丁裔白色个人。最近，申请人 从事研究的重点是拉丁裔人的酒精使用以及少数民族的压力，因为它涉及到 拉丁裔人的吸烟行为。因此，申请人建议在其过去和最近的基础上， 研究经验，以及她的临床训练，在心理健康和遵循一个合乎逻辑的，但新颖的， 从以前的研究和培训经验发展到新的专门知识领域， 在可能受到影响的拉丁裔人中设计和评估酒精和焦虑相关过程 与少数民族有关的压力源。导师将提供一组模范高级调查员，并将 促进候选人在这一新的研究领域的发展。申请人提出了一项全面的 培训计划包括五个领域的发展：（1）与以下相关的理论和经验知识 拉丁裔成年人中危险饮酒和焦虑背景下的少数民族压力模型，（2）高级 通过生态瞬时评估（EMA）的纵向研究设计，（3）经验性回避 (EA)作为一个transdiagnosis机制，（4）先进的分析训练，（5）先进的研究技能， 研究传播、领导力和影响力。通过这一融资机制，候选人的 拟议的研究旨在：（1）检查微攻击（MA）的影响-日常生活的简短，微妙的形式 基于种族/族裔地位的歧视-关于饮酒动机和危险饮酒，（2）审查 （3）通过对焦虑体验的评估，探讨这些关系的机制 MA通过EA对酒精和焦虑相关过程的间接影响，以及（4）探索 酒精和焦虑相关的过程，包括文化特异性结构（例如，种族认同，familisimo， 200名危险饮酒者的拉丁裔成年人的文化适应压力。此外，我们要求澄清， MAs与非歧视性的日常压力源和公开的种族主义不同，并且更具影响力。 拟议成果。这一建议被概念化为翻译研究的一个典型例子， 可以从多方法的框架来解释机制，以增强我们对复杂少数群体的理解 压力和危险的饮酒和焦虑的关系，并作为催化剂，为未来的工作，在这一新兴的 在健康不平等群体中。从这一建议中获得的知识和经验将使 具有独特技能的候选人，以推进这一重要但未充分研究的领域的知识。

PROJECT SUMMARY/ABSTRACT This is an application for a Mentored Patient-Oriented Research Career Development Award (K23) to support the academic career development of the applicant. The candidate's long-term goal is to become an independent clinical investigator and leader in the theoretical understanding, treatment, and intervention of hazardous drinking and anxiety among Latinx persons. The applicant has conducted research on transdiagnostic processes (predominantly anxiety sensitivity) and their association to health behavior research (predominately focused on smoking) among non-Latinx White individuals. More recently, the applicant has engaged in research focused on alcohol use among Latinx individuals as well as minority stress as it relates to smoking behaviors among Latinx persons. Thus, the applicant proposes to build on her past and more recent research experience, as well as her clinical training, in mental health and follows a logical, but novel, progression from prior research and training experiences to development of a new area of expertise in the design and evaluation of alcohol- and anxiety-related processes among Latinx persons who may be impacted by minority-related stressors. Mentorship will be provided by a group of exemplar senior investigators and will foster the candidate's development in this new area of research. The applicant proposes a comprehensive training plan that includes development in five areas: (1) theoretical and empirical knowledge relevant to minority stress models in the context of hazardous drinking and anxiety among Latinx adults, (2) advanced longitudinal research design through Ecological Momentary Assessments (EMA), (3) experiential avoidance (EA) as a transdiagnostic mechanism, (4) advanced analytic training, and (5) advanced research skills in research dissemination, leadership, and grantsmanship. Through this funding mechanism, the candidate’s proposed study aims to: (1) examine the influence of microaggressions (MAs) – brief, subtle forms of everyday discrimination due to racial/ethnic status – on alcohol use motivation and hazardous drinking, (2) examine the influence of MAs on anxiety experience, (3) explore the mechanisms underlying these relations by evaluating the indirect effects of MAs on alcohol- and anxiety-related processes via EA, and (4) explore moderators of alcohol- and anxiety-related processes, including cultural-specific constructs (e.g., ethnic identity, familisimo, acculturative stress among 200 Latinx adults who are hazardous drinkers. Moreover, we seek to elucidate if MAs are distinct from, and more impactful than, non-discriminatory daily stressors and overt racism on the proposed outcomes. This proposal is conceptualized as a prototypical example of translational research that can explicate mechanisms from a multi-method framework to enhance our understanding of complex minority stress and hazardous drinking and anxiety relations and serve as a catalyst for future work in this emerging domain among a health disparities group. The knowledge and experience gained from this proposal will equip the candidate with a unique set of skills to advance knowledge in this important but understudied area.