Tuskegee University Center for Biomedical Research/ RCMI

塔斯基吉大学生物医学研究中心/ RCMI

• 批准号: 10809404
• 负责人: Deepa Bedi
• 金额: $ 460.08万
• 依托单位: TUSKEGEE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-07-07 至 2028-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10809404
• 关键词: Address; Affect; African American population; Alabama; Applications Grants; Area; Behavioral; Behavioral Research; Bioethics; Bioinformatics; Biological Sciences; Biomedical Research; Biometry; Black race; Clinical; Collaborations; Communities; Community Outreach; Computational Biology; Core Facility; County; Dedications; Deep South; Development; Doctor of Philosophy; Education; Educational process of instructing; Educational workshop; Environment; Ethnic Population; Evaluation; Exercise; Extramural Activities; Faculty; Fostering; Foundations; Funding; Goals; Health; Health Disparities Research; Health Personnel; Heart; Human Resources; Infrastructure; Institution; International; Learning; Location; Malignant neoplasm of cervix uteri; Maps; Mentors; Mentorship; Minority; Minority Groups; Minority Health Research; Minority-Serving Institution; Mission; Molecular; National Institute on Minority Health and Health Disparities; Obesity; Outcome Assessment; Population; Population Research; Positioning Attribute; Postdoctoral Fellow; Productivity; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Resources; STEM career; Science; Science, Technology, Engineering and Mathematics Education; Scientific Advances and Accomplishments; Scientist; Services; Solid; Training; Trust; Underrepresented Minority; Underrepresented Populations; Underserved Population; Universities; University adminstration; Vocational Guidance; Work; Workforce Development; career; career development; collaborative environment; community based research; community engagement; community organizations; design; empowerment; health disparity; health inequalities; instrumentation; inter-institutional; learning community; malignant breast neoplasm; member; minority health; minority health disparity; minority scientist; minority student; multidisciplinary; outreach services; programs; racial disparity; racial minority; recruit; research and development; research facility; research faculty; skills; synergism; undergraduate student

PROJECT SUMMARY The overall objective of the Tuskegee University Center for Biomedical Research/Research Centers in Minority Institutions (TU CBR/RCMI) Program is to build upon and expand the University’s research infrastructure and develop researchers to conduct research related to health disparities. This initiative is centered around: 1) providing the necessary infrastructure, resources, services, and technical support to enhance the ability of the University’s researchers to stay on the cutting-edge of multidisciplinary basic biomedical/clinical health/ and population research focused on health disparities; 2) supporting the research and career development of post-doctoral fellows, junior- and mid-level investigators; and 3) enhancing the research excellence by facilitating the recruitment of competitive and highly expert research scientist. These objectives are to be achieved primarily through the following aims: 1) Provide pilot-level funding to support the development and expansion of the research capacity of TU; 2) Provide core research facilities equipped with the infrastructure, instrumentation, and personnel to support the needs of the TU research community; 3) Engage the community through RCMI-sponsored activities that include the research faculty; 4) Expand the clinical health research component in the current initiative; and 5) Provide mentorship and career guidance to enhance the transition of junior-level investigators into independent scientists. The overall goal of the CBR/RCMI project (2023-2028) is to continue the development of its 4 core components, Administrative, Investigator Development, Research Infrastructure and Community Outreach infrastructure and increase the numbers and skill proficiency of minority scientists engaged in scientific areas that includes basic biomedical, clinical health and population research focused on health disparities. The three scientific areas, basic biomedical, clinical health and population research have research objectives focused on breast cancer, obesity and cervical cancer, all of which disproportionately affect African Americans and underrepresented minorities. The goal is to continue support for a competitive, multidisciplinary collaborative environment that advances these scientific areas of research. Tuskegee University has distinctive strengths because it is located in the heart of the Southeast, a region with a large, historically underserved, African American population, and it has a large number of minority faculty members as well as undergraduate and graduate trainees. The goal of the CBR/RCMI will be accomplished through establishment of three synergistic research cores, with services to enable investigative research on health inequities among minority groups, especially African-Americans residing in the ‘Black Belt’ counties of Alabama.

项目摘要 塔斯基吉大学生物医学研究中心的总体目标 少数民族机构中心（TU CBR/RCMI）计划是建立在和扩大 大学的研究基础设施和发展研究人员进行与健康有关的研究 差距。该倡议的核心是：1）提供必要的基础设施，资源， 服务和技术支持，以提高大学的研究人员留在 多学科基础生物医学/临床健康/和人口研究的前沿 关注健康差距; 2）支持博士后的研究和职业发展 研究员、初级和中级研究员;以及3）通过以下方式提高研究的卓越性 促进征聘具有竞争力和高度专业的研究科学家。这些目标 主要通过以下目标实现：1）提供试点资金， 发展和扩大TU的研究能力; 2）提供核心研究设施 配备基础设施、仪器和人员，以支持TU的需求 研究社区; 3）通过RCMI赞助的活动参与社区，包括 4）扩大目前倡议中的临床卫生研究部分; 及5）提供导师及职业辅导，以促进初级人员的过渡 独立科学家的调查。CBR/RCMI项目的总体目标（2023-2028） 继续发展其4个核心组成部分，即行政、调查员 发展、研究基础设施和社区外联基础设施，并增加 从事科学领域的少数民族科学家的人数和技能熟练程度， 生物医学、临床健康和人口研究的重点是健康差距。三 科学领域，基础生物医学，临床卫生和人口研究有研究 目标集中在乳腺癌，肥胖和宫颈癌，所有这些都不成比例地 影响非裔美国人和代表性不足的少数民族。目标是继续支持一个 竞争，多学科的合作环境，推动这些科学领域的发展， research.塔斯基吉大学有独特的优势，因为它位于心脏的 东南部，一个拥有大量历史上服务不足的非洲裔美国人的地区， 大量的少数民族教师以及本科生和研究生实习生。的 通过建立以下三个协同研究项目，将实现CBR/RCMI的目标 核心，并提供服务，以便能够对少数群体之间的卫生不公平现象进行调查研究， 特别是居住在亚拉巴马“黑带”县的非洲裔美国人。

项目成果

The Role of Computational Epidemiology and Risk Analysis in the Fight Against HIV/AIDS.

计算流行病学和风险分析在抗击艾滋病毒/艾滋病中的作用。

• DOI: 10.4172/2155-6113.1000e107
• 发表时间: 2012
• 期刊: Journal of AIDS & clinical research
• 作者: Tameru,Berhanu;Nganwa,David;Bogale,Asseged;Robnett,Vinaida;Habtemariam,Tsegaye
• 通讯作者: Habtemariam,Tsegaye

How to empower a community? Helping communities take control of their health destiny.

如何赋能社区？

• DOI: 10.1016/j.pmedr.2018.12.001
• 发表时间: 2019
• 期刊: Preventive medicine reports
• 影响因子: 2.8
• 作者: Hannon,Lonnie

Anti-cancer activity of heteroaromatic acetals of andrographolide and its isomers.

• DOI: 10.1039/d2nj01055k
• 发表时间: 2022-05-24
• 期刊: NEW JOURNAL OF CHEMISTRY
• 影响因子: 3.3
• 作者: Tamang, Nitesh;Andrews, Christopher;Mavileti, Sai Kiran;Nanduri, Srinivas;Golakoti, Nageswara Rao;Karanam, Balasubramanyam
• 通讯作者: Karanam, Balasubramanyam

Benzopyrylium salts as new anticancer, antibacterial, and antioxidant agents.

• DOI: 10.1007/s00044-020-02685-3
• 发表时间: 2021-04
• 期刊: Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents
• 作者: Kar S;Akhir A;Chopra S;Ohki S;Karanam B;Golakoti NR
• 通讯作者: Golakoti NR

Elevated Protein Kinase A Activity in Stomach Mesenchyme Disrupts Mesenchymal-epithelial Crosstalk and Induces Preneoplasia.

• DOI: 10.1016/j.jcmgh.2022.06.001
• 发表时间: 2022
• 期刊: CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
• 影响因子: 7.2
• 作者: Puri, Pawan;Grimmett, Garfield;Faraj, Rawah;Gibson, Laurielle;Gilbreath, Ebony;Yoder, Bradley K.
• 通讯作者: Yoder, Bradley K.