HOW ENVIRONMENTAL TOXINS AFFECT PERCEPTUAL DEVELOPMENT

描述：铅和二硫化碳对测量的影响 使用小鸡模型评估认知和感觉功能。 具体目标包括确定： 声音，B）区分相似声音之间的微小差异，以及c） 模式感知将用于解决听觉/认知功能的缺陷 在卵内暴露于铅和二硫化碳后的功能。 是 预计来自拟议研究的数据将提供 为随后提交的初步数据， 接触的关键时期以及与其他化学品 环境污染，如噪音和有毒物质。

DESCRIPTION: The effects of lead and carbon disulfide on the measurement of cognitive and sensory function will be assessed using a chick model. Specific aims include determination of: a) ability to detect low-level sound, b) discriminate small differences between similar sounds, and c) pattern perception will be used to resolve deficits in auditory/cognitive function following in ovo exposure to lead and carbon disulfide. It is anticipated that data derived from the proposed studies will provide preliminary data for a subsequent submission aimed at quantification of critical periods of exposure and synergistic effects with other environmental insults such as noise and toxicants.