Multidisciplinary K12 Urologic Research Career Development Program at Baylor

描述（由申请人提供）：本申请寻求贝勒医学院斯科特泌尿科多学科K12泌尿研究（KURe）职业发展计划的支持。该项目的研究重点是下尿路症状，男性生殖生物学和不育症，以及儿科泌尿外科/泌尿生殖系统发育。培训师资队伍包括10名博士/医学博士1名博士导师和5名医学博士临床顾问。Lamb博士将担任KURe的项目主任，Boone博士将担任联合主任。主要研究领域包括：细胞生物学，类固醇激素受体和生长因子信号，男性生殖生物学，遗传学，衰老，儿科泌尿学/发育生物学和基因破坏。受训者将是博士研究员，医学博士研究员/初级教员。我们的项目吸引了高素质的学员，他们寻求在男性健康研究方面进行密集和实质性的研究培训，重点是临床翻译。我们有一个明确的招聘计划，强调招聘妇女和少数民族。培训环境的优势包括备受尊敬，资金充足，经验丰富的教师，NIH对泌尿科的资助在全国排名靠前，结构化的指导和试点项目计划和必修课程，细胞生物学研究生计划，在细胞生物学和遗传学方面都有相关课程和深度。我们的长期目标是培养这些年轻的研究者成功地竞争同行评议的资金，并最终增加泌尿学研究的基础和转化研究的努力。

DESCRIPTION (provided by applicant): This application seeks support for a Multidisciplinary K12 Urologic Research (KURe) Career Development Program at the Scott Department of Urology at Baylor College of Medicine. The research emphasis of this program is in the areas of Lower Urinary Tract Symptoms, male reproductive biology and infertility, as well as pediatric urology/genitourinary development. The training faculty includes 10 Ph.D/M.D., Ph.D. mentors and 5 M.D. clinical advisors. Dr. Lamb will serve as Program Director and Dr. Boone as Co-Director of the KURe. The major research areas in the program include: cell biology, steroid hormone receptors and growth factor signaling, male reproductive biology, genetics, aging, pediatric urology/developmental biology and gene disruption. The trainees will be Ph.D. fellows, M.D. fellows/Junior Faculty. Our program attracts highly qualified trainees who seek an intensive and substantial research training in men's health research with an emphasis on clinical translation. We have a defined recruitment plan that emphasizes the recruitment of women and minorities. The strengths of the training environment include highly respected, well-funded, experienced faculty, the high national ranking for NIH funding of a Urology department, a structured mentoring and pilot project program and required coursework, a cell biology graduate program with relevant course work and depth in both cell biology and genetics. Our long-term goal is to train these young investigators to successfully compete for peer-reviewed funding and eventually to increase basic and translational research efforts in urologic research. PUBLIC HEALTH RELEVANCE: This application focuses on a plan to train young Urologists and Ph.D. fellows in basic and translation research in areas of Urology relating to problems of lower urinary tract symptoms (benign prostatic hyperplasia, erectile dysfunction and bladder storage and voiding problems), birth defects and the controls of basic testis and genital tract function.