Multidisciplinary K12 Urologic Research Career Development Program at Baylor

描述（由申请人提供）：本申请寻求对贝勒医学院斯科特泌尿系多学科K12泌尿学研究（KURe）职业发展计划的支持。该计划的研究重点是下尿路症状，男性生殖生物学和不育症，以及儿科泌尿学/泌尿生殖发育领域。培训教师包括10名博士/医学博士，博士导师和5个医学博士临床顾问兰姆博士将担任项目主任，布恩博士将担任KURe的联合主任。该计划的主要研究领域包括：细胞生物学，类固醇激素受体和生长因子信号传导，男性生殖生物学，遗传学，衰老，儿科泌尿学/发育生物学和基因破坏。学员将获得博士学位。研究员，医学博士研究员/初级教员。我们的计划吸引了高素质的学员，他们寻求男性健康研究方面的密集和实质性的研究培训，重点是临床翻译。我们有一个明确的招聘计划，强调招聘妇女和少数族裔。培训环境的优势包括备受尊敬，资金充足，经验丰富的教师，泌尿科NIH资助的高国家排名，结构化的指导和试点项目计划以及所需的课程，细胞生物学研究生课程，相关课程工作和细胞生物学和遗传学的深度。我们的长期目标是培训这些年轻的研究人员成功地竞争同行评审的资金，并最终增加泌尿外科研究的基础和转化研究工作。 公共卫生相关性：此应用程序侧重于培养年轻泌尿科医生和博士的计划。研究员在泌尿学领域进行基础研究和翻译研究，涉及下尿路症状问题（良性前列腺增生、勃起功能障碍、膀胱储尿和排尿问题）、出生缺陷以及基本睾丸和生殖道功能的控制。

DESCRIPTION (provided by applicant): This application seeks support for a Multidisciplinary K12 Urologic Research (KURe) Career Development Program at the Scott Department of Urology at Baylor College of Medicine. The research emphasis of this program is in the areas of Lower Urinary Tract Symptoms, male reproductive biology and infertility, as well as pediatric urology/genitourinary development. The training faculty includes 10 Ph.D/M.D., Ph.D. mentors and 5 M.D. clinical advisors. Dr. Lamb will serve as Program Director and Dr. Boone as Co-Director of the KURe. The major research areas in the program include: cell biology, steroid hormone receptors and growth factor signaling, male reproductive biology, genetics, aging, pediatric urology/developmental biology and gene disruption. The trainees will be Ph.D. fellows, M.D. fellows/Junior Faculty. Our program attracts highly qualified trainees who seek an intensive and substantial research training in men's health research with an emphasis on clinical translation. We have a defined recruitment plan that emphasizes the recruitment of women and minorities. The strengths of the training environment include highly respected, well-funded, experienced faculty, the high national ranking for NIH funding of a Urology department, a structured mentoring and pilot project program and required coursework, a cell biology graduate program with relevant course work and depth in both cell biology and genetics. Our long-term goal is to train these young investigators to successfully compete for peer-reviewed funding and eventually to increase basic and translational research efforts in urologic research. PUBLIC HEALTH RELEVANCE: This application focuses on a plan to train young Urologists and Ph.D. fellows in basic and translation research in areas of Urology relating to problems of lower urinary tract symptoms (benign prostatic hyperplasia, erectile dysfunction and bladder storage and voiding problems), birth defects and the controls of basic testis and genital tract function.