Genetic Basis of Inflammatory Airway Disease

炎症性气道疾病的遗传基础

基本信息

  • 批准号:
    7664316
  • 负责人:
  • 金额:
    $ 39.31万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2007
  • 资助国家:
    美国
  • 起止时间:
    2007-09-27 至 2012-07-31
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): The objectives of this Career Development Program in the Genetics and Genomics of Lung Diseases entitled "Genetic Basis of Inflammatory Airway Disease" are to develop and evaluate a multidisciplinary program that will educate young pulmonary investigators in methods of genetics and genomics to become independent investigators and assume leadership roles in the genetics and genomics of pulmonary diseases. The central focus of this program, inflammatory airway disease, including asthma, cystic fibrosis, and chronic obstructive pulmonary disease, reflects the importance of understanding diverse, complex pulmonary diseases characterized by airway inflammation and exploits the strong commitment of the faculty at Washington University to apply methods in genetics and genomics to investigation of the biological basis of this family of lung diseases. The first year curriculum will include: 1) the established Genetic Epidemiology Masters of Science (GEMS) Training Program sponsored by the Division of Biostatistics; 2) a mentored research experience to insure submission of a manuscript for publication by the summer of the second year; 3) 3 month educational immersion experiences with established pulmonary and genomic teams of investigators; 4) relevant, ongoing conferences, journal clubs, lectures, and courses; and, 5) the NHLBI sponsored Programs for Genomic Applications Traveling Tutorial. The second and third year curriculum will include: 1) continuation of the mentored research experience; 2) additional courses; and, 3) submission of a K Award application. The specific aims of this application include: Specific Aim (1): We will provide fundamental training in genetic epidemiology and biostatistics with emphasis on translational research. Specific Aim (2): We will provide extensive mentoring to the trainees for career development and for developing independent research plans that focus on pulmonary disorders. Specific Aim (3): We will support trainees by helping them prepare independent career development research grants such as KO8 and K23 Awards and by taking full advantage of the extraordinary resources of the participating mentors and institutional environment. Specific Aim (4): We will develop and implement plans for evaluating and tracking the effectiveness and success of these efforts for each trainee up to 2 years after completion of the program. This career development program will train young scientists to use state of the art methods in genetics and genomics to develop new diagnostic and therapeutic strategies for asthma, cystic fibrosis, and COPD. (End of Abstract)
描述(由申请人提供):

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Francis Sessions Cole其他文献

Francis Sessions Cole的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('Francis Sessions Cole', 18)}}的其他基金

Clinical Research Support Core
临床研究支持核心
  • 批准号:
    10682166
  • 财政年份:
    2023
  • 资助金额:
    $ 39.31万
  • 项目类别:
Washington University School of Medicine Undiagnosed Diseases Network Clinical Site
华盛顿大学医学院未确诊疾病网络临床站点
  • 批准号:
    9789913
  • 财政年份:
    2018
  • 资助金额:
    $ 39.31万
  • 项目类别:
Washington University School of Medicine Undiagnosed Diseases Network Clinical Site
华盛顿大学医学院未确诊疾病网络临床站点
  • 批准号:
    9977220
  • 财政年份:
    2018
  • 资助金额:
    $ 39.31万
  • 项目类别:
Lipidomic Screening For Functional Surfactant Gene Mutations
功能性表面活性剂基因突变的脂质组学筛选
  • 批准号:
    9021312
  • 财政年份:
    2014
  • 资助金额:
    $ 39.31万
  • 项目类别:
Lipidomic Screening For Functional Surfactant Gene Mutations
功能性表面活性剂基因突变的脂质组学筛选
  • 批准号:
    8606976
  • 财政年份:
    2014
  • 资助金额:
    $ 39.31万
  • 项目类别:
Genetic Regulation of Surfactant Deficiency
表面活性剂缺乏的基因调控
  • 批准号:
    7824722
  • 财政年份:
    2009
  • 资助金额:
    $ 39.31万
  • 项目类别:
Genetic Regulation of Surfactant Deficiency
表面活性剂缺乏的基因调控
  • 批准号:
    7588777
  • 财政年份:
    2007
  • 资助金额:
    $ 39.31万
  • 项目类别:
Genetic Basis of Inflammatory Airway Disease
炎症性气道疾病的遗传基础
  • 批准号:
    7903439
  • 财政年份:
    2007
  • 资助金额:
    $ 39.31万
  • 项目类别:
Genetic Basis of Inflammatory Airway Disease
炎症性气道疾病的遗传基础
  • 批准号:
    7323914
  • 财政年份:
    2007
  • 资助金额:
    $ 39.31万
  • 项目类别:
Genetic Regulation of Surfactant Deficiency
表面活性剂缺乏的基因调控
  • 批准号:
    7828089
  • 财政年份:
    2007
  • 资助金额:
    $ 39.31万
  • 项目类别:

相似海外基金

Testing the effectiveness of the biological drug, Tezepelumab, in patients with coexisting allergic rhinitis and allergic asthma
测试生物药物 Tezepelumab 对同时患有过敏性鼻炎和过敏性哮喘的患者的有效性
  • 批准号:
    490921
  • 财政年份:
    2022
  • 资助金额:
    $ 39.31万
  • 项目类别:
    Studentship Programs
Air Pollution, Stress and Asthma Morbidity Risk: Role of Biological and Geospatial Markers
空气污染、压力和哮喘发病风险:生物和地理空间标记的作用
  • 批准号:
    10396626
  • 财政年份:
    2021
  • 资助金额:
    $ 39.31万
  • 项目类别:
Air Pollution, Stress and Asthma Morbidity Risk: Role of Biological and Geospatial Markers
空气污染、压力和哮喘发病风险:生物和地理空间标记的作用
  • 批准号:
    10216007
  • 财政年份:
    2021
  • 资助金额:
    $ 39.31万
  • 项目类别:
Air Pollution, Stress and Asthma Morbidity Risk: Role of Biological and Geospatial Markers
空气污染、压力和哮喘发病风险:生物和地理空间标记的作用
  • 批准号:
    10615633
  • 财政年份:
    2021
  • 资助金额:
    $ 39.31万
  • 项目类别:
Sex as a biological variable: Immunomodulatory mechanisms of Innate Defence Regulator (IDR) peptides in asthma
性别作为生物变量:先天防御调节剂 (IDR) 肽在哮喘中的免疫调节机制
  • 批准号:
    449782
  • 财政年份:
    2020
  • 资助金额:
    $ 39.31万
  • 项目类别:
    Studentship Programs
Potential biological mechanisms with regard to the association betwen asthma and obesity
哮喘与肥胖之间关联的潜在生物学机制
  • 批准号:
    17K09599
  • 财政年份:
    2017
  • 资助金额:
    $ 39.31万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Childhood Asthma, Susceptibility and Biological Activity of Ambient Particles
儿童哮喘、环境颗粒物的易感性和生物活性
  • 批准号:
    7434307
  • 财政年份:
    2008
  • 资助金额:
    $ 39.31万
  • 项目类别:
Childhood Asthma, Susceptibility and Biological Activity of Ambient Particles
儿童哮喘、环境颗粒物的易感性和生物活性
  • 批准号:
    8092713
  • 财政年份:
    2008
  • 资助金额:
    $ 39.31万
  • 项目类别:
Childhood Asthma, Susceptibility and Biological Activity of Ambient Particles
儿童哮喘、环境颗粒物的易感性和生物活性
  • 批准号:
    7685408
  • 财政年份:
    2008
  • 资助金额:
    $ 39.31万
  • 项目类别:
Phenotypic and biological features of mucus plugs in asthma
哮喘粘液栓的表型和生物学特征
  • 批准号:
    10654049
  • 财政年份:
    2005
  • 资助金额:
    $ 39.31万
  • 项目类别:
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了