Molecular and Cellular Research to Advance Child Health

促进儿童健康的分子和细胞研究

• 批准号: 7578304
• 负责人: Michael Artman
• 金额: $ 42.31万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-02-20 至 2012-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7578304
• 关键词: Advisory Committees; Animal Model; Applied Genetics; Area; Arts; Basic Science; Biological; Biology; Cardiovascular system; Child health care; Childhood; Clinical; Development; Disease; Educational Curriculum; Effectiveness; Environment; Faculty; Feedback; Fostering; Future; Genetic; Genomics; Goals; Health; Host Defense; Institutes; Instruction; Iowa; K-Series Research Career Programs; Medical; Medicine; Mentors; Minority; Molecular; Molecular Genetics; Molecular and Cellular Biology; Operative Surgical Procedures; Pediatric Research; Physicians; Physiological; Physiology; Problem Solving; Program Reviews; Recruitment Activity; Regulation; Research; Research Personnel; Research Training; Schedule; Scientist; Training; Translational Research; Universities; Whole Organism; Woman; base; career; career development; child well being; college; design; gene function; human disease; improved; innovation; meetings; pediatric department; programs

DESCRIPTION (provided by applicant): This application seeks ongoing support for the University of Iowa Child Health Research Career development program in response to RFA HD-00-020. The purpose is to support the research career development of pediatricians who have recently completed subspecialty training. The application is to continue a program that provides core support for laboratories and administrative resources applicable to a number of research projects that address the molecular biology of development. These include the identification and localization of genes in the human genome, mechanisms by which specific genes regulate the synthesis of gene products, and gene targeting and gene transfer to study gene function in developing tissues. The P.I., Program Director, and Established Investigators whose funded research is closely related to the focus of the CHRCDA will act as an advisory committee to select from highly qualified new faculty pediatrician scientists three recipients of New Project Development Funds at all times. Each of the Scholars will conduct investigations under guidance of one or more identified Established Investigators. Each will perform molecular biologic procedures in a Shared Core Laboratory that is supported in part by University matching funds and is under the supervision of a Core Laboratory Director. Scholars supported by the award also may spend other periods of time working in the laboratories of their respective Established Investigators. This arrangement will provide cost-effective, quality- controlled, instrumentation and procedure performance to Scholars. Scholars will attend lectures, seminars and formal graduate courses on research ethics, as well as on molecular biology techniques and strategies in developmental biology. Measures to attract women and minority pediatricians to research careers have been incorporated. The program is anticipated to capitalize on an institutional infrastructure of interdisciplinary research and will build upon a departmental tradition of research career development. It will promote productivity and collaboration, and speed the application of new basic science discoveries to clinical care.

描述（由申请人提供）：本申请寻求对爱荷华州大学儿童健康研究职业发展计划的持续支持，以响应RFA HD-00-020。其目的是支持最近完成专科培训的儿科医生的研究职业发展。该应用程序是继续一个程序，提供适用于一些研究项目，解决发展的分子生物学的实验室和行政资源的核心支持。这些包括人类基因组中基因的识别和定位，特定基因调节基因产物合成的机制，以及基因靶向和基因转移以研究发育组织中的基因功能。私家侦探，项目主任和既定的研究人员，其资助的研究与CHRCDA的重点密切相关，将作为一个咨询委员会，从高素质的新教师儿科科学家中选择三名新项目发展基金的接受者。每个学者将在一个或多个确定的既定调查员的指导下进行调查。每个人都将在共享核心实验室进行分子生物学程序，该实验室部分由大学配套资金支持，并在核心实验室主任的监督下进行。该奖项支持的学者也可以花其他时间在各自的既定研究人员的实验室工作。这种安排将为学者提供具有成本效益、质量受控的仪器和程序性能。学者们将参加讲座，研讨会和正式的研究生课程的研究伦理，以及在发育生物学的分子生物学技术和战略。已经纳入了吸引妇女和少数民族儿科医生从事研究工作的措施。该计划预计将利用跨学科研究的机构基础设施，并将建立在研究职业发展的部门传统。它将促进生产力和协作，并加快新的基础科学发现在临床护理中的应用。