Neuro-cCMV: determining the contribution of congenital CMV infection to brain malformations and white matter disorders

Neuro-cCMV：确定先天性 CMV 感染对脑畸形和白质疾病的影响

• 批准号: nhmrc : GNT1165376
• 金额: $ 52.18万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/neuro-ccmv-determining-matter-disorders/1379401
• 关键词: Neuro; cCMV; determining; contribution; congenital

Cytomegalovirus (CMV) infection usually results in no illness at all, or very minor symptoms. Most people will have it at least once in their lives. The developing brain is however very susceptible to CMV infection. Up to one quarter of foetuses exposed to CMV develop brain damage which can lead to cerebral palsy and epilepsy. Our project will study the severe neurological complications of congenital CMV infection, and will try to determine why some babies are more susceptible than others.

巨细胞病毒（CMV）感染通常不会导致任何疾病，或非常轻微的症状。大多数人一生中至少会有一次。然而，发育中的大脑非常容易受到CMV感染。多达四分之一的胎儿暴露于CMV发展脑损伤，可导致脑瘫和癫痫。我们的项目将研究先天性巨细胞病毒感染的严重神经系统并发症，并试图确定为什么有些婴儿比其他婴儿更易感。