Exergame Physical ActivityPainand Functional Mobility Among Women with Knee Ost

描述(由申请者提供)：本申请要求为Bridgett Rahim-Williams博士、博士和公共卫生硕士颁发NCMHD K22差异研究和教育推进使命(DREAM)职业过渡奖。拉希姆-威廉姆斯博士的目标是开发一项独立的研究计划，研究非洲裔美国人和患有膝骨性关节炎(OA)的45-75岁非西班牙裔白人女性在慢性病自我管理方面的少数民族健康和健康差距。拉希姆-威廉姆斯博士目前正在进行探索性研究，研究50-70岁患有膝骨性关节炎的非裔美国人和非西班牙裔白人女性的疼痛、体力活动和功能活动。通过NIH的经验、直接指导、独立研究、科学会议和教学经验，Rahim-Williams博士的职业发展计划将在以下方面为她提供更多的技能、知识和经验：(1)流行病学、高级生物统计调查设计、方法和对导致膝关节骨关节炎健康差异的人群数据和生物心理社会因素的分析；(2)骨关节炎的临床研究，包括评估疾病的严重性，以及膝骨性关节炎的中枢和外周疼痛机制；(3)随机临床试验的设计和实施；以及(4)体力活动和游戏技术方面的技能和知识；应用游戏促进健康干预以改善健康结果。该研究计划的主要目标是利用实验室实验方法确定膝骨性关节炎女性患者的体力活动、疼痛、功能活动和残疾的特征，这些方法包括：(1)新颖和创新的健康游戏(如骑自行车、舞城/舞蹈、舞蹈革命)方法，(2)机械压力测试和(3)体力活动、功能活动和自报残疾的评估。这项研究项目的目标是增加身体活动，改善功能活动，并减少膝盖骨关节炎患者的疼痛和残疾结果。K22梦想奖将促进拉希姆-威廉姆斯博士从少数族裔健康和健康差距研究人员的早期阶段过渡到独立阶段，即研究人员发起的健康差距研究，利用新的健康游戏自我管理少数族裔妇女的疼痛和慢性病。

DESCRIPTION (provided by applicant): This application requests a NCMHD K22 Disparities Research and Education Advancing Mission (DREAM) Career Transition Award for Dr. Bridgett Rahim-Williams, PhD, MPH. Dr. Rahim-Williams' goal is to develop an independent program of research studying minority health and health disparities in chronic disease self-management among African American, and non-Hispanic white women ages 45-75 with knee osteoarthritis (OA). Dr. Rahim-Williams is currently engaged in exploratory research that examines pain, exergame physical activity and functional mobility among African American and non-Hispanic White women ages 50-70 with knee OA. Through NIH experience, direct mentoring, independent study, scientific meetings, and didactic experiences, Dr. Rahim-Williams' career development plan will provide her with expanded skills, knowledge and experience in: (1) epidemiological, advanced bio- statistics survey design, methods, and analysis of population-based data and biopsychosocial factors contributing to health disparities in knee OA; (2) clinical research in osteoarthritis, including assessment of disease severity, and central and peripheral pain mechanisms in knee osteoarthritis, (3) design and conduct of randomized clinical trials, and (4) skills and knowledge in physical activity and exergaming technology; Games for Health intervention applied to improve health outcomes. The main objectives of the research plan are to characterize physical activity, pain, functional mobility and disability among women with knee OA using experimental laboratory methods that include: (1) novel and innovative Games for Health (e.g. exergame cycling, DanceTown/Dance, Dance Revolution) methods, (2) mechanical pressure testing and (3) assessment of physical activity, functional mobility and self-reported disability. The goal of this research project is to increase physical activity, improve functional mobility, and reduce pain and disability outcomes for women affected by knee OA. The K22 DREAM award will facilitate Dr. Rahim-Williams' transition from the early stage as a minority health and health disparities researcher to the independent stage of investigator-initiated health disparities research utilizing novel games for health for self-management of pain and chronic disease among minority women.