Neurocognitive studies of reward sensitivity in opiate addiction and its influence on addiction-related behaviour

阿片成瘾奖赏敏感性的神经认知研究及其对成瘾相关行为的影响

• 批准号: nhmrc : 628495
• 负责人: Prof Daniel Lubman
• 金额: $ 17.22万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/neurocognitive-studies-reward-related-behaviour/95563
• 关键词: Neurocognitive; studies; reward; sensitivity; opiate

Drug abuse is the greatest single preventable risk factor for physical illness and death in Australians . Our understanding of the neural and cognitive mechanisms that contribute to the transition from drug use to addiction is not yet complete. The current proposal investigates cognitive control dysfunction, most notably the impulsivity for reward seen in drug addiction that is known to predict the transition from drug use to addiction and relapse during treatment.

药物滥用是澳大利亚人身体疾病和死亡的最大可预防的单一风险因素。我们对促进从吸毒到成瘾的神经和认知机制的了解还不完整。目前的提案调查了认知控制功能障碍，最明显的是在吸毒成瘾中出现的对奖励的冲动，众所周知，这种冲动可以预测从吸毒到成瘾和治疗期间的复发。