Training in the pharmacology of abused drugs

滥用药物药理学培训

基本信息

  • 批准号:
    9386216
  • 负责人:
  • 金额:
    --
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2016
  • 资助国家:
    美国
  • 起止时间:
    2016-12-01 至 2017-06-30
  • 项目状态:
    已结题

项目摘要

 DESCRIPTION (provided by applicant): We are requesting continued funding of this productive training program to prepare pre-doctoral and postdoctoral fellows to become independent scholars in studying the biomedical aspects of drugs of abuse. The training record of this program is outstanding, due to the quality of the trainees and preceptors and its organizational structure. Competition for support from this program has been strong and all slots have been full. Trainees are expected to be supported by this program for no more than 3 years. Since 2010, 13 pre-doctorals and 6 postdoctorals have earned individual NIH fellowships. A large number of individuals who received training from these preceptors have progressed to become leaders in the drug abuse field and a very impressive number have earned funding from NIDA and other sources for their substance abuse-related research. Since the submission of our last competitive application we have recruited three new faculty from other institutions and two faculty members from other departments in this university. The recruitment of more clinical faculty is seen as significant. Thus we are requesting support for 10 predoctoral trainees an increase of one, and we will maintain our postdoctoral trainees at 6. Our preceptors provide the trainees with "cutting edge" expertise in molecular, cellular, behavioral, clinical and translational research. The major emphasis of this program continues to be concentrated on the pharmacology and mechanism of action of abused drugs and mechanisms of addiction. We continue to have a broad scope in our training program and expect that each preceptor will bring his or her specific expertise to the benefit of all trainees. This is accomplished through the wide variety of courses, the high level of collaboration among the mentors, the faculty serving on thesis committees and our excellent seminar series. We also have two new core facilities, one devoted to the development of genetically altered animals and the other to a sophisticated bioanalytical technology. The program has enjoyed and will continue to benefit from strong administrative support from the Department of Pharmacology and Toxicology and the administration of the school and university. The predoctoral training program is rigorous and is characterized by two years of required course work and participation in excellent research projects. Postdoctoral fellows will concentrate on research throughout their training. The major emphasis of all training supported by this program is on research. The faculty has earned the research support necessary for the trainees through the significant number of grants they have generated. We will provide guidance on research, teaching and the professionalism for a career in biomedical science and all aspects of becoming a productive and independent researcher. This will continue to be the hallmark of this program as we continue to provide the atmosphere for the training of leading scholars in the drug abuse field for the future.
 描述(由申请人提供):我们请求继续资助这一富有成效的培训计划,以帮助博士前和博士后研究员成为研究滥用药物生物医学方面的独立学者。由于学员和导师的素质及其组织结构,该项目的培训记录非常出色。对该计划支持的竞争非常激烈,所有名额均已满。预计学员获得该计划的支持时间不超过 3 年。自2010年以来,已有13名博士前和6名博士后获得了NIH个人奖学金。许多接受过这些导师培训的人已经成为药物滥用领域的领导者,其中相当多的人获得了 NIDA 和其他来源的资助,用于与药物滥用相关的研究。自从提交上次竞争性申请以来,我们已经从其他机构招聘了三名新教师,从这所大学的其他部门招聘了两名教师。招聘更多临床教师被认为意义重大。因此,我们请求支持 10 名博士前学员,增加 1 名,并将博士后学员维持在 6 名。我们的导师为学员提供分子、细胞、行为、临床和转化研究方面的“尖端”专业知识。该计划的主要重点仍然集中在滥用药物的药理学和作用机制以及成瘾机制。我们的培训计划将继续保持广泛的范围,并期望每位导师都能利用他或她的具体专业知识造福所有学员。这是通过广泛的 多样化的课程、导师之间的高水平合作、论文委员会的教师以及我们出色的研讨会系列。我们还拥有两个新的核心设施,一个致力于转基因动物的开发,另一个致力于复杂的生物分析技术。该计划已经并将继续受益于药理学和毒理学系以及学校和大学管理部门的强有力的行政支持。博士前培训计划严谨,特点是两年的必修课程和参与优秀的研究项目。博士后研究员将在整个培训过程中专注于研究。该计划支持的所有培训的主要重点是研究。教师通过获得大量资助,为学员赢得了必要的研究支持。我们将为生物医学科学的职业生涯以及成为一名富有成效的独立研究人员的各个方面提供研究、教学和专业精神方面的指导。这将继续成为该项目的标志,因为我们将继续为未来药物滥用领域顶尖学者的培训提供氛围。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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William L. Dewey其他文献

A comparison of some pharmacological actions of morphine and Δ9-tetrahydrocannabinol in the mouse
  • DOI:
    10.1007/bf00426745
  • 发表时间:
    1978-01-01
  • 期刊:
  • 影响因子:
    3.300
  • 作者:
    Alan S. Bloom;William L. Dewey
  • 通讯作者:
    William L. Dewey
Derivatives of Apomorphine and of Other <em>N</em>-Substituted Norapomorphines
  • DOI:
    10.1002/jps.2600651129
  • 发表时间:
    1976-11-01
  • 期刊:
  • 影响因子:
  • 作者:
    Edward R. Atkinson;S.P. Battista;Istvan E. Ary;Donald G. Richardson;Louis S. Harris;William L. Dewey
  • 通讯作者:
    William L. Dewey
Mo1598 - Colonic Supernatants from Chronic Morphine Exposed Mice Induce Morphine Tolerance in Naïve Dorsal Root Ganglion Neurons that is Mitigated by Oral Vancomycin Delivery
  • DOI:
    10.1016/s0016-5085(17)32537-4
  • 发表时间:
    2017-04-01
  • 期刊:
  • 影响因子:
  • 作者:
    Ryan Mischel;William L. Dewey;Hamid I. Akbarali
  • 通讯作者:
    Hamid I. Akbarali
Excretion of <em>trans</em>-Δ<sup>9</sup>-Tetrahydrocannabinol and Its Metabolites in Intact and Bile Duct-Cannulated Rats
  • DOI:
    10.1002/jps.2600620506
  • 发表时间:
    1973-05-01
  • 期刊:
  • 影响因子:
  • 作者:
    Robert F. Turk;Louis S. Harris;William L. Dewey
  • 通讯作者:
    William L. Dewey
Mo1578 - The Effect of a G-Protein Biased Ligand, TRV130, on Opioid-Induced Constipation
  • DOI:
    10.1016/s0016-5085(18)32629-5
  • 发表时间:
    2018-05-01
  • 期刊:
  • 影响因子:
  • 作者:
    Joanna C. Jacob;Bethany David;Aliyeen Khan;William L. Dewey;Hamid I. Akbarali
  • 通讯作者:
    Hamid I. Akbarali

William L. Dewey的其他文献

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{{ truncateString('William L. Dewey', 18)}}的其他基金

The Central Virginia Center on Drug Abuse Research
弗吉尼亚中部药物滥用研究中心
  • 批准号:
    10604263
  • 财政年份:
    2013
  • 资助金额:
    --
  • 项目类别:
The Central Virginia Center on Drug Abuse Research
弗吉尼亚中部药物滥用研究中心
  • 批准号:
    9189703
  • 财政年份:
    2013
  • 资助金额:
    --
  • 项目类别:
The Central Virginia Center on Drug Abuse Research
弗吉尼亚中部药物滥用研究中心
  • 批准号:
    10374821
  • 财政年份:
    2013
  • 资助金额:
    --
  • 项目类别:
The Central Virginia Center on Drug Abuse Research
弗吉尼亚中部药物滥用研究中心
  • 批准号:
    8552155
  • 财政年份:
    2013
  • 资助金额:
    --
  • 项目类别:
Administrative Core
行政核心
  • 批准号:
    10374822
  • 财政年份:
    2013
  • 资助金额:
    --
  • 项目类别:
Administrative Core
行政核心
  • 批准号:
    10604264
  • 财政年份:
    2013
  • 资助金额:
    --
  • 项目类别:
The Role of Protein Kinase C in Opioid Tolerance
蛋白激酶 C 在阿片类药物耐受中的作用
  • 批准号:
    7278267
  • 财政年份:
    2006
  • 资助金额:
    --
  • 项目类别:
The Role of Protein Kinase C in Opioid Tolerance
蛋白激酶 C 在阿片类药物耐受中的作用
  • 批准号:
    7465564
  • 财政年份:
    2006
  • 资助金额:
    --
  • 项目类别:
The Role of Protein Kinase C in Opioid Tolerance
蛋白激酶 C 在阿片类药物耐受性中的作用
  • 批准号:
    7148489
  • 财政年份:
    2006
  • 资助金额:
    --
  • 项目类别:
The Role of Protein Kinase C in Opioid Tolerance
蛋白激酶 C 在阿片类药物耐受中的作用
  • 批准号:
    7652489
  • 财政年份:
    2006
  • 资助金额:
    --
  • 项目类别:

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