Training Program in Cancer Prevention and Control for Priority Populations

重点人群癌症预防和控制培训项目

• 批准号: 9789853
• 负责人: Guy H Montgomery
• 金额: $ 33.53万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-21 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9789853
• 关键词: Cancer Control; Population; Training Programs; cancer prevention

PROJECT ABSTRACT More than 600,000 Americans will die of cancer in 2017. While cancer affects the entire US population, it has the distinct feature of striking disparities in incidence and mortality across several `priority' populations such as racial/ethnic minorities, the low-income, and the elderly, reflecting differences in risk factors and access to prevention and treatments. The National Cancer Institute highlighted the interplay of environment, biology and behavior as determinants of cancer outcomes in priority populations and the need for its integration in cancer prevention and control (CPC) efforts, signaling a greater need for multidisciplinary approaches to CPC research for priority populations. Such complex approaches require developing highly trained research scientists with a multidisciplinary `mindset': the enthusiasm and appreciation for working across disciplines to gain new perspectives on old problems and develop innovative solutions. And yet, the development pipeline for such investigators is inadequate to match the growing burden of cancer and cancer risk in priority populations. The overarching goal of the proposed CPC postdoctoral research training program is to launch the careers of a new generation of clinical and non-clinical researchers prepared to apply this multidisciplinary approach to CPC research targeting priority populations. The program's goals are to: 1) Provide a tailored curriculum integrating biological, medical, epidemiologic, behavioral, and community perspectives in CPC research in priority populations; 2) Promote interdisciplinary approaches to CPC research; and 3) Foster multidisciplinary research careers in CPC among trainees through mentored research. To successfully execute these aims, the program will recruit candidates who show promise as future multidisciplinary CPC investigators; provide outstanding mentorship; foster a multidisciplinary team science environment; and facilitate the attainment of academic career and life skills needed to pursue and sustain long term success as independent investigators. The program's strengths will lie in the diverse CPC research portfolio at Mount Sinai, its integration in the newly NCI-accredited Tisch Cancer Institute, the network of methodologically diverse and accomplished mentors, and Mount Sinai's long history of serving the socioeconomically, racially and ethnically diverse communities that comprise its catchment area. It is modeled after our highly successful prior R25T Behavioral CPC training program. The program will matriculate 2 candidates each year for the 2-year fellowship, training a total of 10 new investigators over 5 years. Each trainee will develop a highly tailored curriculum in consultation with their mentors and the Program Directors. The curricula will be rooted in the 11 core competencies needed to start a successful career in multidisciplinary CPC research targeting priority populations. Trainees will have a primary and secondary mentor(s), and their progress will be carefully monitored by a Mentorship Committee. The program will receive guidance from expert internal and external advisory boards, and its performance will be regularly monitored through select metrics to ensure continued improvement, growth, and sustainability.

项目摘要 2017年将有超过60万美国人死于癌症。虽然癌症影响整个美国人口，但它 若干“优先”人群的发病率和死亡率差异显著， 少数种族/族裔、低收入者和老年人，反映出风险因素和获得 预防和治疗。国家癌症研究所强调了环境、生物学和 行为是优先人群癌症结局的决定因素，需要将其纳入癌症治疗 预防和控制（CPC）的努力，表明更需要多学科的方法来CPC 研究重点人群。这种复杂的方法需要发展训练有素的研究 具有多学科“心态”的科学家：对跨学科工作的热情和赞赏， 对老问题有新的看法，并开发创新的解决方案。然而， 这些调查人员不足以应付重点人群日益增加的癌症负担和癌症风险。 拟议的CPC博士后研究培训计划的总体目标是启动一个 新一代的临床和非临床研究人员准备应用这种多学科方法， 保护竞争委员会针对重点人群的研究。该计划的目标是：1）提供定制的课程 在CPC研究中整合生物学、医学、流行病学、行为学和社区观点， 2）促进CPC研究的跨学科方法; 3）促进多学科的研究。 通过指导研究，在学员中开展CPC研究职业。为了成功地实现这些目标， 该计划将招募有希望成为未来多学科CPC调查员的候选人;提供 杰出的导师;培养多学科团队科学环境;并促进实现 学术生涯和生活技能需要追求和维持长期的成功作为独立的调查。 该计划的优势将在于西奈山多样化的CPC研究组合，其在 新的NCI认证的Tisch癌症研究所，方法多样和完成的网络 导师，和西奈山的服务社会经济，种族和民族多样性的悠久历史 包括其集水区的社区。它是仿照我们之前非常成功的R25 T行为 CPC培训计划。该计划将录取2名候选人，每年为2年的奖学金，培训 5年内共聘用10名新调查员。每位学员将在咨询中制定高度定制的课程 与他们的导师和项目主管一起。课程将以所需的11项核心能力为基础 在针对重点人群的多学科CPC研究中开始成功的职业生涯。学员将有 一个小学和中学导师（S），他们的进展将由一个指导委员会密切监测。 该计划将得到内部和外部专家咨询委员会的指导，其绩效将 通过选定的指标进行定期监控，以确保持续改进、增长和可持续性。