Enhancing the public health benefits of mammography screening by informing women of both breast cancer and breast arterial calcification results: A randomized trial to promote cardiovascular health
通过告知女性乳腺癌和乳腺动脉钙化结果,增强乳房 X 光检查的公共健康益处:一项促进心血管健康的随机试验
基本信息
- 批准号:10211939
- 负责人:
- 金额:$ 70.26万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-04-01 至 2026-03-31
- 项目状态:未结题
- 来源:
- 关键词:AffectAppointmentArteriesBehaviorBreastBreast Cancer DetectionCardiac DeathCardiologyCardiovascular DiseasesCardiovascular systemCaringCause of DeathCommunicationCommunitiesComplementConsentControl GroupsCoronary ArteriosclerosisCoronary arteryDataDemographic FactorsDetectionDiagnosisDietDigital MammographyEnsureEthnic OriginFailureGeneral PopulationGoalsHealth BenefitHealth behaviorHeartImageInterventionIntervention StudiesLearningLengthLettersLife StyleLiteratureMalignant NeoplasmsMammographic screeningMammographyMeasuresMediatingMedicalModelingMyocardialMyocardial InfarctionOutcomeOutcome StudyParticipantPatient PreferencesPatientsPopulation StudyPostmenopausePrevalencePreventionPreventivePreventive careProcessPsychological FactorsPublic HealthRaceRadiationRandomizedRecommendationReportingResearchSamplingScreening for cancerScreening procedureSymptomsTestingTextTimeUnited StatesVisitWaiting ListsWomanWomen&aposs Healthbasecalcificationcancer preventioncardiovascular healthcoronary artery calcificationdesigndisorder riskethnic diversityfollow-uphealth dataimprovedinnovationlifestyle factorsmalignant breast neoplasmprimary outcomeracial diversityradiologistrandomized trialrecruitroutine screeningscreening
项目摘要
Breast mammography is one of the most successful cancer screening tools in the cancer prevention arsenal. 37 million women in the US will receive a mammogram this year, and following that, these women will receive a letter letting them know whether they do or do not have evidence of breast cancer. Recent research indicates that standard digital mammography also yields additional information critical to women’s health; that is, information about the presence of calcifications within breast arteries - breast arterial calcification (BAC). The presence of BAC has been associated with calcification within coronary arteries, which is a marker of coronary artery disease (CAD). Research indicates that at least 12.7% of women’s mammograms reveal BAC – about 1 in 8. Of those with BAC, 32%-96% have CAD. Thus, conservatively, mammography could detect over 1.5 million cases of CAD each year. Despite this potential public health boon, BAC information is not directly communicated to patients in the post-mammography letter. The failure to communicate BAC status is a missed opportunity to inform women about CAD risk, and is inconsistent with patient preferences. The goal of this proposal is to investigate whether provision of BAC information to women post-mammography influences their cardiovascular health behaviors. We will randomize mammography patients whose imaging reveals BAC (N=1,889, English and Spanish-speaking) to either: a) the BAC-Enhanced letter condition which informs women about their positive BAC findings and the BAC-CAD association, encourages women to seek preventive cardiology care, and provides cardiology referral information; or b) the Waitlist Control condition, where patients receive a standard mammography letter initially and learn their BAC status 6 months later. We hypothesize that women who receive the BAC-Enhanced letter will be more likely to attend a cardiovascular health appointment (primary outcome), engage in heart healthy behavior, and have CAD detected. Guided by the Common Sense Model, we seek to understand which psychological factors mediate the relationship between the intervention and the outcomes. Also, most BAC prevalence literature has been conducted on predominantly white samples. To remedy this, we will describe BAC prevalence in a large, racially and ethnically diverse sample (N=14,875). Innovation: This will be the first study of an intervention to directly share BAC information with women undergoing mammography in a “direct to consumer” approach, and the first to report BAC prevalence in a racially and ethnically diverse sample. Public health impact: The project is a first step towards ensuring that women benefit directly from all of the rich health data that mammography can yield.
乳房x光检查是癌症预防中最成功的癌症筛查工具之一。今年,美国将有3700万女性接受乳房x光检查,之后,这些女性将收到一封信,告知她们是否有乳腺癌的证据。最近的研究表明,标准的数字乳房x光检查还能提供对妇女健康至关重要的额外信息;即乳腺动脉钙化的信息——乳腺动脉钙化(BAC)。BAC的存在与冠状动脉钙化有关,这是冠状动脉疾病(CAD)的标志。研究表明,至少12.7%的女性乳房x光检查显示BAC,约为八分之一。在BAC患者中,32%-96%患有CAD。因此,保守地说,乳房x光检查每年可以发现超过150万例CAD病例。尽管这种潜在的公共卫生福利,BAC信息并没有在乳房x光检查后的信件中直接传达给患者。未能沟通BAC状态错失了告知女性CAD风险的机会,并且与患者偏好不一致。本提案的目的是调查乳腺x光检查后提供BAC信息是否会影响她们的心血管健康行为。我们将随机分配影像学显示BAC的乳房x光检查患者(N=1,889,英语和西班牙语):a) BAC增强字母条件,告知女性BAC阳性结果和BAC- cad关联,鼓励女性寻求预防性心脏病护理,并提供心脏病转诊信息;b)候补名单控制条件,患者最初收到标准的乳房x光检查信,并在6个月后了解他们的BAC状态。我们假设收到bac增强信的女性将更有可能参加心血管健康预约(主要结局),从事心脏健康行为,并检测到CAD。在常识模型的指导下,我们试图理解哪些心理因素调解了干预与结果之间的关系。此外,大多数BAC患病率文献主要是在白人样本上进行的。为了弥补这一点,我们将描述一个大的、种族和民族多样化的样本中的BAC患病率(N=14,875)。创新:这将是第一个以“直接面向消费者”的方式与接受乳房x光检查的女性直接分享BAC信息的干预研究,也是第一个报告不同种族和民族样本中BAC患病率的研究。公共卫生影响:该项目是确保妇女直接受益于乳房x光检查可产生的所有丰富健康数据的第一步。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Guy H Montgomery其他文献
Effects of trauma history on cancer-related screening, diagnosis, and treatment
创伤史对癌症相关筛查、诊断和治疗的影响
- DOI:
10.1016/s1470-2045(23)00438-2 - 发表时间:
2023-11-01 - 期刊:
- 影响因子:35.900
- 作者:
Deborah C Marshall;Lauren M Carney;Kristin Hsieh;Daniel R Dickstein;Margaret Downes;Advaita Chaudhari;Shauna McVorran;Guy H Montgomery;Julie B Schnur - 通讯作者:
Julie B Schnur
Guy H Montgomery的其他文献
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{{ truncateString('Guy H Montgomery', 18)}}的其他基金
Enhancing the public health benefits of mammography screening by informing women of both breast cancer and breast arterial calcification results: A randomized trial to promote cardiovascular health
通过告知女性乳腺癌和乳腺动脉钙化结果,增强乳房 X 光检查的公共健康益处:一项促进心血管健康的随机试验
- 批准号:
10380781 - 财政年份:2022
- 资助金额:
$ 70.26万 - 项目类别:
Enhancing the public health benefits of mammography screening by informing women of both breast cancer and breast arterial calcification results: A randomized trial to promote cardiovascular health
通过告知女性乳腺癌和乳腺动脉钙化结果,增强乳房 X 光检查的公共健康益处:一项促进心血管健康的随机试验
- 批准号:
10634705 - 财政年份:2022
- 资助金额:
$ 70.26万 - 项目类别:
Training clinical providers in evidence-based hypnosis for cancer pain management
对临床提供者进行癌症疼痛管理循证催眠培训
- 批准号:
10597587 - 财政年份:2020
- 资助金额:
$ 70.26万 - 项目类别:
Training Program in Cancer Prevention and Control for Priority Populations
重点人群癌症预防和控制培训项目
- 批准号:
10628864 - 财政年份:2018
- 资助金额:
$ 70.26万 - 项目类别:
Training Program in Cancer Prevention and Control for Priority Populations
重点人群癌症预防和控制培训项目
- 批准号:
9789853 - 财政年份:2018
- 资助金额:
$ 70.26万 - 项目类别:
Training Program in Cancer Prevention and Control for Priority Populations
重点人群癌症预防和控制培训项目
- 批准号:
10238055 - 财政年份:2018
- 资助金额:
$ 70.26万 - 项目类别:
Training Program in Cancer Prevention and Control for Priority Populations
重点人群癌症预防和控制培训项目
- 批准号:
10469343 - 财政年份:2018
- 资助金额:
$ 70.26万 - 项目类别:
Training providers in CBT plus Hypnosis - an evidence-based fatigue intervention
CBT 加催眠培训提供者 - 一种基于证据的疲劳干预措施
- 批准号:
8997819 - 财政年份:2015
- 资助金额:
$ 70.26万 - 项目类别:
Training providers in CBT plus Hypnosis - an evidence-based fatigue intervention
CBT 加催眠培训提供者 - 一种基于证据的疲劳干预措施
- 批准号:
9148261 - 财政年份:2015
- 资助金额:
$ 70.26万 - 项目类别:
Training providers in CBT plus Hypnosis - an evidence-based fatigue intervention
CBT 加催眠培训提供者 - 一种基于证据的疲劳干预措施
- 批准号:
9769650 - 财政年份:2015
- 资助金额:
$ 70.26万 - 项目类别:
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