Training Program in Cancer Prevention and Control for Priority Populations

项目摘要 虽然癌症影响着整个美国人口，但美国各地的发病率和死亡率存在着惊人的差异。 少数民族、低收入者和老年人等“优先”群体， 风险因素的差异以及获得预防和治疗的机会。国家癌症研究所强调， 多层次因素的相互作用决定了优先人群的癌症结局， 在癌症预防和控制（CPC）工作的整合。因此，培养训练有素的研究科学家 具有多学科的“心态”以及对跨学科工作的热情和欣赏， 新的视角和开发创新的解决方案是至关重要的。然而，这样的开发管道 研究人员的能力不足以应对优先人群中日益增长的癌症负担和癌症风险。 我们的计划在其第一个融资周期中取得了巨大成功，招募了一批非常多样化的 学员，有100%的毕业生在全职学术CPC研究生涯，75%已经 获得外部K（或同等）资金。这个CPC博士后更新的总体目标 研究培训计划是继续推出新一代的临床和非临床的职业生涯 研究人员准备将这种多学科方法应用于针对优先人群的CPC研究。 为了成功地实现这一目标，该计划将继续招募有才华的早期职业研究人员， 致力于在学术界，政府，基金会或行业的CPC研究事业，重点是 提供多学科辅导、指导和个性化职业发展 计划为来自不同背景的研究人员推出成功的研究生涯;培养欣赏力 在学员和能力作为多学科CPC研究团队的一部分工作;并促进 获得独立追求和维持长期成功所需的研究事业和生活技能 研究人员，团队科学的积极参与者，以及CPC的未来领导者。我们的培训计划的优势 在于西奈山多样化的CPC研究组合，其在NCI认证的Tisch Cancer 研究所，网络的方法多样化和成就的导师，和西奈山的悠久历史， 服务于构成其集水区的社会经济、种族和民族多样化的社区 区我们的计划每年录取2名候选人参加为期2年的奖学金，共培训10名新的 5年以上的调查。每个学员都开发了一个高度定制的课程，植根于12个核心能力 需要在针对优先人群的多学科CPC研究中开始成功的职业生涯。学员 有一个主要和次要的导师，他们的进展是仔细监测的导师 以马克思该计划接受专家内部和外部咨询委员会的指导， 通过选定的衡量标准定期监测业绩，以确保持续改进和可持续性。

PROJECT ABSTRACT While cancer affects the entire US population, there are striking disparities in incidence and mortality across several `priority' populations such as racial/ethnic minorities, low-income, and older adults, reflecting differences in risk factors and access to prevention and treatments. The National Cancer Institute highlighted the interplay of multilevel factors determining cancer outcomes in priority populations and the need for its integration in cancer prevention and control (CPC) efforts. Thus, developing highly trained research scientists with a multidisciplinary `mindset' and the enthusiasm and appreciation for working across disciplines to gain new perspectives and develop innovative solutions is critical. Yet, the development pipeline for such investigators is inadequate to match the growing burden of cancer and cancer risk in priority populations. Our program has been highly successful in its first funding cycle with recruitment of a very diverse group of trainees, having 100% of graduates in full-time academic CPC research careers, and 75% having already obtained external K (or equivalent) funding. The overarching goal of the renewal of this CPC postdoctoral research training program is to continue to launch the careers of a new generation of clinical and non-clinical researchers prepared to apply this multidisciplinary approach to CPC research targeting priority populations. To successfully execute this goal, the program will continue to recruit talented early career researchers who are committed to careers in CPC research in academia, government, foundations or industry, with emphasis on priority populations; provide multidisciplinary mentorship, guidance and individualized career development plans to launch successful research careers for investigators from diverse backgrounds; foster appreciation among trainees for and ability to work as part of multidisciplinary CPC research teams; and facilitate the attainment of a research career and life skills needed to pursue and sustain long term success as independent investigators, active participants in team science, and future leaders in CPC. Our training program's strengths lie in the diverse CPC research portfolio at Mount Sinai, its integration in the NCI-accredited Tisch Cancer Institute, the network of methodologically diverse and accomplished mentors, and Mount Sinai's long history of serving the socioeconomically, racially and ethnically diverse communities that comprise its catchment area. Our program matriculates 2 candidates each year for the 2-year fellowship, training a total of 10 new investigators over 5 years. Each trainee develops a highly tailored curriculum rooted in 12 core competencies needed to start a successful career in multidisciplinary CPC research targeting priority populations. Trainees have a primary and secondary mentor(s), and their progress is carefully monitored by a Mentorship Committee. The program receives guidance from expert internal and external advisory boards, and its performance is regularly monitored through select metrics to ensure continued improvement and sustainability.