Immunological Mechanisms of Disease Training Program
疾病免疫机制培训计划
基本信息
- 批准号:9791561
- 负责人:
- 金额:$ 29.41万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-08-05 至 2024-07-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
SUMMARY
The Vanderbilt University School of Medicine Immunological Mechanisms of Disease Training
Program (IMDTP) will fill a much-needed gap in the training of basic immunologic mechanisms of
human disease. The clinical translation of basic science immunology to benefit human health now
requires the development of scientists with appreciation of both inflammation and the tissues in which
it occurs. The primary focus of the IMDTP will be to provide pre- and postdoctoral trainees with the
expertise necessary to make novel discoveries in basic immunology and to translate these
discoveries to human disease. The IMDTP will provide trainees a skill set to address how the immune
system is regulated and functions in complex tissues in human disease by integrating basic
immunology and principles of pathology with a particular emphasis on chronic, inflammatory
diseases, and cancer. A long-term goal of the IMDTP will be to not only train the next generation of
research scientists in basic immunology, but to emphasize the importance of using acquired
knowledge as a translational platform on which to develop new therapies and interventions with a
high regard for responsible conduct of research and reproducibility. We plan to use an
interdisciplinary training approach building upon the Vanderbilt University program in Molecular
Pathology and Immunology. The training faculty has been specifically recruited from the greater
Vanderbilt scientific community conducting immunology-based research of chronic inflammatory
diseases and consists of twenty-six highly productive faculty with successful mentoring records. In
order to also allow for the training of future mentors, three mentors are at the Assistant Professor
level. All of the faculty mentors have successful histories training predoctoral and postdoctoral
scientists and have primary interests in immune- and inflammatory-based mechanisms of disease.
These research programs will provide highly developed, diverse, and interdisciplinary training
opportunities. All trainees will acquire and expand their skills in critical thinking, oral and written
communication and interrogation of the literature. These primary functions of the IMDTP will be
facilitated through our bi-weekly immunology and pathology seminar series and annual research
symposium. Training will include participation in courses and modules on both basic immunology and
pathology of disease processes. In addition, we will provide each trainee with the necessary
instruction on responsible conduct in science, rigor and reproducibility in research and information on
alternative career options. Funds are requested to support three predoctoral and two postdoctoral
trainees. Thoughtful mentoring of these trainees, made possible by the IMDTP, will ensure the future
of translational research focused on immunologic mechanisms of disease.
总结
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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{{ truncateString('AMY S MAJOR', 18)}}的其他基金
Investigating mechanisms of oxidized phospholipid-mediated dysregulation of regulatory T cells in atherosclerosis
研究动脉粥样硬化中氧化磷脂介导的调节性 T 细胞失调的机制
- 批准号:
10648711 - 财政年份:2023
- 资助金额:
$ 29.41万 - 项目类别:
Fc Receptors in Atherosclerosis: Linking Innate and Adaptive Immunity.
Fc§§ 动脉粥样硬化受体:连接先天免疫和适应性免疫。
- 批准号:
10450688 - 财政年份:2021
- 资助金额:
$ 29.41万 - 项目类别:
Fc Receptors in Atherosclerosis: Linking Innate and Adaptive Immunity.
Fc§§ 动脉粥样硬化受体:连接先天免疫和适应性免疫。
- 批准号:
10664909 - 财政年份:2021
- 资助金额:
$ 29.41万 - 项目类别:
Fc Receptors in Atherosclerosis: Linking Innate and Adaptive Immunity.
Fc§§ 动脉粥样硬化受体:连接先天免疫和适应性免疫。
- 批准号:
10259917 - 财政年份:2021
- 资助金额:
$ 29.41万 - 项目类别:
Targeting Tfh Cell Metabolic Regulation in SLE and SLE-Associated Atherosclerosis
针对 SLE 和 SLE 相关动脉粥样硬化的 Tfh 细胞代谢调节
- 批准号:
10029497 - 财政年份:2020
- 资助金额:
$ 29.41万 - 项目类别:
Targeting Tfh Cell Metabolic Regulation in SLE and SLE-Associated Atherosclerosis
针对 SLE 和 SLE 相关动脉粥样硬化的 Tfh 细胞代谢调节
- 批准号:
10609478 - 财政年份:2020
- 资助金额:
$ 29.41万 - 项目类别:
Targeting Tfh Cell Metabolic Regulation in SLE and SLE-Associated Atherosclerosis
针对 SLE 和 SLE 相关动脉粥样硬化的 Tfh 细胞代谢调节
- 批准号:
10380090 - 财政年份:2020
- 资助金额:
$ 29.41万 - 项目类别:
Immunological Mechanisms of Disease Training Program
疾病免疫机制培训计划
- 批准号:
10640277 - 财政年份:2019
- 资助金额:
$ 29.41万 - 项目类别:
Immunological Mechanisms of Disease Training Program
疾病免疫机制培训计划
- 批准号:
10413896 - 财政年份:2019
- 资助金额:
$ 29.41万 - 项目类别:
Targeting the T cell immune synapse in autoimmunity
自身免疫中靶向 T 细胞免疫突触
- 批准号:
9406059 - 财政年份:2017
- 资助金额:
$ 29.41万 - 项目类别: