Development of minocycline as a neuroimmune therapy for alcohol use disorder

开发米诺环素作为酒精使用障碍的神经免疫疗法

• 批准号: 10378321
• 负责人: Daniel Roche
• 金额: $ 3.14万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-05 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10378321
• 关键词: Administrative Supplement; Birth; COVID-19 pandemic; Caregivers; Child; Childbirth; Development; Direct Costs; Grant; K-Series Research Career Programs; Manuscripts; Mentored Research Scientist Development Award; Mentors; Minocycline; Neuroimmune; Paternity Leave; Productivity; Research; Research Assistant; Research Project Grants; Role; Training; United States National Institutes of Health; Wife; alcohol use disorder; care providers; career development; experience; interest; research study; response

Project Summary/Abstract This supplement application is in response to the Notice of Special Interest (NOT-OD-20-054): Administrative Supplements to Promote Research Continuity and Retention of NIH Mentored Career Development (K) Award Recipients and Scholars. The PI is in the fourth year of his K01 Mentored Research Scientist Development Award, and his wife gave birth to their first child on 05/18/2020. The PI and his wife have alternated being the sole care providers over the past 10+ months since childbirth. The PI was on official paternity leave until 12/14/20, and his role as sole caregiver until this return date significantly impeded his manuscript and grant productivity, K01 training experiences, and K01 research study progress; all difficulties were further compounded due to the COVID-19 pandemic. The PI is requesting 6 months of research assistant support ($29,092 in direct costs) to support the completion of his delayed K01 research project and to facilitate his return to full productivity post-childbirth.

项目总结/摘要 本补充申请是对特别关注通知（NOT-OD-20-054）的回应： 促进研究连续性和NIH指导职业保留的行政补充 发展（K）奖获得者和学者。PI是在他的K 01指导研究的第四年 科学家发展奖，他的妻子在2020年5月18日生下了他们的第一个孩子。私家侦探和他的妻子 在分娩后的过去10个多月里，一直是唯一的护理提供者。PI是官方的 陪产假至2020年12月14日，在此返回日期之前，他作为唯一照顾者的角色严重妨碍了他的工作。 论文和资助生产率、K 01培训经验和K 01研究进展;所有困难 因COVID-19疫情而进一步恶化。PI要求6个月的研究助理 支持（直接费用为29，092美元），以支持完成其延迟的K 01研究项目，并促进 他在产后恢复了全部生产力。