Development of minocycline as a neuroimmune therapy for alcohol use disorder

项目摘要/摘要 本补充申请是对特别关注通知(NOT-OD-20-054)的回应： 促进研究连续性和保留NIH指导职业的行政补充 发展(K)奖获得者和学者。PI是他K01指导研究的第四年 科学家发展奖获得者，他的妻子于2020年5月18日生下了他们的第一个孩子。少年派和他的妻子 在分娩后的10多个月里，他们交替成为唯一的照顾者。私家侦探是官方的 直到12/14/20的陪产假，以及在此之前作为唯一照顾者的角色严重阻碍了他的 手稿和赠款生产率、K01培训经验和K01研究性学习进展；所有困难 由于新冠肺炎大流行，情况进一步恶化。私家侦探要求6个月的研究助理 支持(29,092美元的直接费用)，以支持其延迟的K01研究项目的完成，并促进 他在分娩后恢复了完全的生产力。

Project Summary/Abstract This supplement application is in response to the Notice of Special Interest (NOT-OD-20-054): Administrative Supplements to Promote Research Continuity and Retention of NIH Mentored Career Development (K) Award Recipients and Scholars. The PI is in the fourth year of his K01 Mentored Research Scientist Development Award, and his wife gave birth to their first child on 05/18/2020. The PI and his wife have alternated being the sole care providers over the past 10+ months since childbirth. The PI was on official paternity leave until 12/14/20, and his role as sole caregiver until this return date significantly impeded his manuscript and grant productivity, K01 training experiences, and K01 research study progress; all difficulties were further compounded due to the COVID-19 pandemic. The PI is requesting 6 months of research assistant support ($29,092 in direct costs) to support the completion of his delayed K01 research project and to facilitate his return to full productivity post-childbirth.