Supraspinal Control of Human Locomotor Adaptation
人类运动适应的脊髓上控制
基本信息
- 批准号:10377086
- 负责人:
- 金额:$ 7.27万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-01-01 至 2023-03-31
- 项目状态:已结题
- 来源:
- 关键词:AnkleAnteriorAreaBalance trainingBasic ScienceBehaviorBiomechanicsBrainBrain imagingCerebellumCerebral DominanceCognitionConsensusDataDiagnosisElectrodesElectroencephalographyEquilibriumExcisionFunctional Magnetic Resonance ImagingGaitGait speedGoalsHeadHumanImageImaging technologyLaboratoriesLeadLegLimb structureLiteratureLocomotionLocomotor adaptationMeasuresModelingMonitorMorphologic artifactsMotionMotorMotor CortexMovement DisordersNervous System TraumaNoisePaperParietal LobePeer ReviewPerformanceProcessPublishingResearch PersonnelRoboticsRunningSignal TransductionSomatosensory CortexSpeedSystemTechnologyTestingTrainingUnited States National Institutes of HealthUpper ExtremityVisualWalkingWorkbaseblood oxygen level dependentbrain computer interfacecingulate cortexdata repositorydensitydisabilityexoskeletonfoothuman subjectimaging modalityimprovedinnovationinsightlocomotor controllocomotor tasksmind controlnovelpublic health relevancerelating to nervous systemrobot exoskeletonsignal processingsomatosensorytemporal measurementtreadmillwalking speed
项目摘要
Title
Supraspinal Control of Human Locomotor Adaptation
Abstract
Advances in electroencephalography (EEG) technology have made it feasible to study electrical brain dynamics
during human gait. Active electrodes, novel signal processing approaches, and subject-specific inverse electrical
head models allow for unprecedented insight into how the human brain controls locomotion. Further advances
in EEG based mobile brain imaging will increase our fundamental understanding of how the human brain works
in real world situations, improve diagnosis and treatment of movement disorders, and result in new brain-
computer interfaces. We recently developed a novel noise-cancelling EEG system that can greatly improve the
signal to noise ratio for EEG. We propose to use our novel EEG system to investigate human locomotor
adaptation. Many studies have used blood-oxygen-level dependent imaging (e.g. fMRI or fNIRS) to study
supraspinal control of upper limb motor adaptation or imagined human walking, but the timescale of those
imaging modalities do not allow for identifying brain activity relative to the biomechanics of the gait cycle. We
propose to use our novel EEG system to document the brain areas involved in locomotor adaptation. Specifically,
we will quantify brain activity spectral fluctuations within the gait cycle that demonstrate correlations with
locomotor adaptation. We expect that multiple brain areas, including the anterior cingulate, cerebellum,
somatosensory cortex, and motor cortex are likely involved in the control and adaptation of walking. We also
expect that areas involved in locomotor adaptation will decrease spectral power fluctuations with improvements
in locomotor performance during challenging gait tasks. The specific tasks that we will investigate are walking at
different speeds, walking on a split-belt treadmill, walking with a unilateral robotic ankle exoskeleton, and walking
on a balance beam with visual perturbations. The high temporal resolution of EEG provides particularly valuable
insight into both amplitude and timing of brain activity within the gait cycle. Our preliminary data suggest that
there are more cortical areas involved in controlling human walking than are generally recognized in the literature.
The results from these studies will increase our basic science understanding of the supraspinal control of human
locomotor adaptation and should lead to further advances in EEG mobile brain imaging technology.
标题
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Daniel P Ferris其他文献
Daniel P Ferris的其他文献
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{{ truncateString('Daniel P Ferris', 18)}}的其他基金
Supraspinal Control of Human Locomotor Adaptation
人类运动适应的脊髓上控制
- 批准号:
10426056 - 财政年份:2018
- 资助金额:
$ 7.27万 - 项目类别:
Supraspinal Control of Human Locomotor Adaptation
人类运动适应的脊髓上控制
- 批准号:
10671884 - 财政年份:2018
- 资助金额:
$ 7.27万 - 项目类别:
Supraspinal Control of Human Locomotor Adaptation
人类运动适应的脊髓上控制
- 批准号:
10667742 - 财政年份:2018
- 资助金额:
$ 7.27万 - 项目类别:
Supraspinal Control of Human Locomotor Adaptation
人类运动适应的脊髓上控制
- 批准号:
9531486 - 财政年份:2018
- 资助金额:
$ 7.27万 - 项目类别:
Electrical Neuroimaging of Brain Processes during Human Gait
人类步态期间大脑过程的电神经成像
- 批准号:
8727116 - 财政年份:2011
- 资助金额:
$ 7.27万 - 项目类别:
Electrical Neuroimaging of Brain Processes during Human Gait
人类步态期间大脑过程的电神经成像
- 批准号:
8532061 - 财政年份:2011
- 资助金额:
$ 7.27万 - 项目类别:
Electrical Neuroimaging of Brain Processes during Human Gait
人类步态期间大脑过程的电神经成像
- 批准号:
8236146 - 财政年份:2011
- 资助金额:
$ 7.27万 - 项目类别:
Electrical Neuroimaging of Brain Processes during Human Gait
人类步态期间大脑过程的电神经成像
- 批准号:
8322574 - 财政年份:2011
- 资助金额:
$ 7.27万 - 项目类别:
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