Imaging and Radiation Oncology Core (IROC) Group

影像和放射肿瘤学核心 (IROC) 小组

• 批准号: 10376892
• 负责人: MICHAEL V KNOPP
• 金额: $ 39.9万
• 依托单位: AMERICAN COLLEGE OF RADIOLOGY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-05-26 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10376892
• 关键词: Aftercare; American College of Radiology; Clinical Management; Clinical Trials; Clinical Trials Cooperative Group; Clinical Trials Design; Communication; Communication Programs; Consultations; Credentialing; Data; Data Collection; Data Set; Development; Digital Imaging and Communications in Medicine; Disease; Ensure; Funding; Grant; Image; Information Systems; Information Technology; Infrastructure; Leadership; Location; Malignant Neoplasms; Methodology; Modality; Modernization; National Cancer Institute; National Clinical Trials Network; Ohio; Oncology Group; Outcome; Patient imaging; Patients; Philadelphia; Principal Investigator; Procedures; Process; Radiation Oncology; Radiation therapy; Recommendation; Rhode Island; Secure; Services; Site; Subgroup; Technical Expertise; Technology; Time; Uncertainty; Universities; Vision; Washington; Work; cancer clinical trial; clinical imaging; clinical trial analysis; data acquisition; data management; effective therapy; member; operation; organizational structure; programs; prospective; protocol development; quality assurance; therapy outcome; tool; trial design

The primary objective of the Imaging and Radiation Oncology (IROC) Group is to provide scientific and technical expertise for incorporation of appropriate, integrated quality Assurance (QA) and image data management for both imaging and radiotherapy (RT) in applicable trials conducted by the National Clinical Trials Network (NCTN) Program and other NCI funded clinical trial groups (NCORP and ETCTN). The physical IROC QA Centers are distributed in 4 main locations and are administratively organized through the American College of Radiology (ACR). The QA Centers include IROC Houston, IROC Ohio, IROC Rhode Island, and IROC Philadelphia. The Advanced Technology QA Center (ATC) located at Washington University, St. Louis will provide their expertise and consultation services to IROC as needed. IROC capitalizes on existing infrastructure and expertise at QA centers currently providing services to the NCI’s clinical trial programs. Work flows, processes and information systems have been enhanced taking into account the best practices and standards in an integrated vision across NCI’s clinical trials. The interdependencies between imaging and RT are synergized eliminating duplication of services and optimizing efficient and effective workflows. A major strength of IROC is the development of consistent standard operating procedures for all imaging and RT aspects of the NCTN, NCORP and ETCTN (NCI Groups) and to facilitate a seamless flow of imaging and RT patient case datasets across the networks. IROC’s organizational structure allows the delivery of a broad array of imaging and RT QA services including Site Qualification; Trial Design Support; Credentialing; Data Management (Pre- and Post-treatment Case Review); and Case Review. An information technology infrastructure is used that harmonizes IROC services, data collection, assessment and management for the NCI Groups’ clinical trials. IROC implements programs that assure consistent high quality imaging and RT planning/delivery across the NCTN participating sites. IROC members collaborate with the NCI, NCI Groups, and disease/modality committees within each Network Group to provide an optimum and effective imaging and RT core service. The IROC Group will analyze QA data obtained prospectively/retrospectively and the correlation it might have with clinical trial outcomes to better determine and prioritize appropriate QA activities that maximize their benefit to clinical trials.

成像和放射肿瘤学（IROC）组的主要目标是 提供科学和技术专门知识， 成像和放射治疗的质量保证（QA）和图像数据管理 (RT)在国家临床试验网络（NCTN）进行的适用试验中 计划和其他NCI资助的临床试验组（NCORP和ETCTN）。物理 IROC QA中心分布在4个主要地点，并在行政上进行组织 美国放射学会（ACR）QA中心包括IROC 休斯顿、俄亥俄州、罗得岛和费城。先进 位于圣路易斯华盛顿大学的技术质量保证中心（ATC）将提供 根据需要向IROC提供专业知识和咨询服务。IROC利用 现有的基础设施和专业知识，目前提供服务的质量保证中心， NCI的临床试验项目。工作流程、流程和信息系统已经 考虑到综合构想中的最佳做法和标准， 在NCI的临床试验中。成像和RT之间的相互依赖性是 协同消除重复服务和优化高效和有效 工作流程。IROC的一个主要优势是开发一致的标准 NCTN、NCORP和ETCTN所有成像和RT方面的操作程序 (NCI组），并促进成像和RT患者病例数据集的无缝流动 在网络上。IROC的组织结构允许提供广泛的 成像和RT QA服务，包括研究中心资格认证;试验设计支持; 资格认证;数据管理（治疗前和治疗后病例审查）;和病例 审查.使用信息技术基础设施，协调IROC 服务，数据收集，评估和管理NCI集团的临床 审判IROC实施了确保一致的高质量成像和RT的计划 在NCTN参与研究中心的规划/交付。IROC成员与 NCI、NCI组和每个网络组内的疾病/模式委员会， 提供最佳和有效的成像和RT核心服务。IROC集团将 分析前瞻性/回顾性获得的QA数据及其可能的相关性 临床试验结果，以更好地确定和优先考虑适当的QA活动 最大限度地提高临床试验的效益。