2022 Sensory Transduction in Microorganisms GRC & GRS

2022年微生物感觉转导GRC

• 批准号: 10374971
• 负责人: Karen M Ottemann
• 金额: $ 0.8万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-11-01 至 2023-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10374971
• 关键词: Address; Allergic Disease; Antibiotics; Antimicrobial Resistance; Applied Research; Area; Bacteria; Bacteriophages; Basic Science; Behavior; Biochemistry; Biology; Biophysics; Cell physiology; Cells; Cellular biology; Chemicals; Collaborations; Communicable Diseases; Communities; Cryo-electron tomography; Data; Development; Disease; Eating; Environment; Event; Fostering; Goals; Health; Human; Image; Immune System Diseases; Immune system; Institutes; Invaded; Knowledge; Life Style; Macromolecular Complexes; Mammals; Methods; Microbial Biofilms; Microbiology; Microfluidics; Mission; Modeling; Molecular; Molecular Genetics; National Institute of Allergy and Infectious Disease; Output; Participant; Pathogenesis; Pathway interactions; Persons; Plants; Postdoctoral Fellow; Process; Property; Research; Research Personnel; Resolution; Role; Science; Scientist; Sensory; Signal Transduction; Specialist; Structure; System; Systems Biology; Techniques; Time; Tissues; Training; Transcriptional Regulation; Underrepresented Populations; United States National Institutes of Health; Virulence; Virulence Factors; Work; antimicrobial; bacterial genetics; base; career; cell motility; combat; design; educational atmosphere; experimental study; fighting; graduate student; host colonization; host-microbe interactions; innovation; interdisciplinary collaboration; interest; macromolecular assembly; mechanotransduction; meetings; microbial; microbial community; microbiome; microbiota; microorganism; pathogen; pathogenic bacteria; posters; prevent; programs; receptor; response; skills; small molecule; success; supportive environment; symposium; synthetic biology

Project summary The 2022 Gordon Research Conference on Sensory Transduction in Microorganisms to be held in Ventura CA in January 2022 will explore recent advances in understanding signal transduction in bacteria, especially pathogens. Focus will be placed on chemosensory mechanisms and pathways, small molecule intracellular signals (e.g. c-di-GMP), two component systems and the cellular processes they regulate as well as mechanisms of bacterial lifestyle decisions including biofilms, bacterial multicellular behavior and predator-prey interactions. The roles of these systems with respect to pathogenesis, antimicrobial resistance, and synthetic biology will be central themes. An important topic for this conference will be host-microbe interactions. All these critical areas will be addressed through cutting-edge applications of molecular genetics, cell biology, biochemistry, and chemical biology as well as structural, imaging, biophysical, and computational approaches. Data from high-resolution experiments will be paired with modeling to understand and predict the behavior of complex macromolecular assemblies and signaling circuitry. Invited speakers will include both established and early-stage investigators using a wide array of approaches. In addition, short talks will be chosen from the abstracts to give additional early-career scientists a chance to speak, and to round on the program. Participants will benefit from the Conference's open, collegial atmosphere that provides multiple opportunities to engage in scientific discussion, promote scientific rigor, and foster interdisciplinary collaboration. New, innovative efforts will be used to increase participation of scientists from historically under-represented backgrounds, and multiple efforts will be taken to make participants feel welcome and valued. For the fifth time, a Gordon Research Seminar (GRS) for postdocs and graduate students will precede the GRC. The GRS provides a supportive environment for young scientists to present their work, make connections, and receive advice by leaders in the field. The STIM community has long supported junior scientists, and we view the success of the GRS as a necessity to continue on this mission. The GRS will help us not only nurture the development of early stage investigators, but also promote diversity within our community. The GRS will help junior scientists gain the confidence and skills to become full-fledged GRC participants. The well-integrated STIM GRC/GRS will direct established investigators to the most important questions confronting our field and will encourage young scientists to apply their recent training to the exciting new areas of microbiology.

项目总结