Administrative Core

通过这个行政核心的活动，我们将提供科学和行政领导以及 监督这一高度协作的U19提案，该提案将部署多种启用基因组学的方法来 调查与高死亡率和发病率相关的病毒、细菌、真菌和寄生虫病原体，分析 可能改变疾病结局的混合感染，并强调为这些患者确定新的药物靶点 难以治疗的感染。GCID的组成部分将包括四个互动研究项目 这将利用我们最先进的技术以及数据管理和传播核心。至 支持这些综合活动，我们将：(1)建立一个执行委员会，负责 所有研究项目和核心的总体科学指导和进展，(2)提供一般行政管理 在每个研究项目和核心一级的支助和财政问责，(3)建立机制，以 与NIAID、外部指导委员会和其他GCID定期沟通，(4)参与 外展和培训活动，以便将基因组学专业知识从我们的GCID转移到传染病 社区，以及(V)与NIAID协商，建立为合作试点项目提供资金的机制 跨GCID，这将进一步推动新技术的开发或探索高优先级研究 传染病方面的话题。

Through the activities in this Administrative Core, we will provide scientific and administrative leadership and oversight for this highly collaborative U19 proposal that will deploy multiple genomics-enabled approaches to investigate viral, bacteria fungal, and parasitic pathogens associated with high mortality and morbidity, analyze co-infections that may alter disease outcome, and emphasize the identification of novel drug targets for those infections that are difficult to treat. The components of this GCID will include four interacting Research Projects that will make use of our state-of-the-art Technology and Data Management and Dissemination Cores. To support these integrated activities we will (i) establish an Executive Committee that will be responsible for overall scientific direction and progress of all Research Projects and Cores, (ii) provide general administrative support and fiscal accountability at the level of each Research Project and Core, (iii) establish mechanisms for regular communication with NIAID, the external Steering Committee, and the other GCIDs, (iv) engage in outreach and training activities in order to transfer genomics expertise from our GCID to the infectious disease community, and (v) in consultation with NIAID, establish a mechanism for funding Collaborative Pilot Projects across GCIDs that will further advance the development of novel technologies or explore high-priority research topics in infectious disease.