Bioinformatics Core

生物信息学核心

• 批准号: 10733195
• 负责人: Andrew V Kossenkov
• 金额: $ 4.62万
• 依托单位: WISTAR INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-01 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10733195
• 关键词: Address; Bioinformatics; Characteristics; Consultations; Data; Data Analyses; Data Security; Development; Ensure; Environment; Experimental Designs; Generations; Goals; Manuscripts; Molecular; Mutation; Pharmacotherapy; Preclinical Testing; Preparation; Process; Progress Reports; Protocols documentation; Quality Control; Research; Research Design; Research Personnel; Research Project Grants; Research Proposals; Sample Size; Statistical Data Interpretation; Writing; data management; experimental study; mRNA Expression; melanoma; member; preclinical study; programs; protein expression; treatment response

Project Summary – Bioinformatics Core C The Bioinformatics Core will conduct bioinformatics and statistical analyses of data generated by the projects and cores to address research hypotheses defined in the project-specific proposals. The core will also perform integrative analyses to combine data from all experiments. The PDX Core will provide central storage, data management and information security for generated raw and processed high throughput data within the PDX Development and Trial Center (PDTC). The core will assist with preparation and writing of progress reports, abstracts, manuscripts, and future research proposals. During the span of the Research Program, the Bioinformatics Core will ensure timely progress tracking of PDX trials and sharing of generated results between members of the PTDC.

项目摘要-生物信息学核心C 生物信息学核心将对项目产生的数据进行生物信息学和统计分析 和核心，以解决在特定项目的建议书中定义的研究假设。核心也将执行 综合分析以将来自所有实验的数据联合收割机组合。PDX Core将提供中央存储、数据 PDX内生成的原始数据和处理后的高吞吐量数据的管理和信息安全 开发和试验中心（PDTC）。该核心将协助编写进度报告， 摘要，手稿和未来的研究计划。在研究计划期间， 生物信息学核心将确保及时跟踪PDX试验的进展，并在 PTDC的成员。