Networking and Expanding Undergraduate Research on the Neurobiology of Aging to Advance Diversity
网络化和扩大衰老神经生物学本科研究以促进多样性
基本信息
- 批准号:10705045
- 负责人:
- 金额:$ 38.64万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-09-30 至 2027-05-31
- 项目状态:未结题
- 来源:
- 关键词:AddressAgingAlzheimer&aposs disease related dementiaAreaAutomobile DrivingAwarenessBachelor&aposs DegreeBehavioralBiologicalBlack raceBrainClinicalCognitiveCognitive agingCollaborationsCommunicationCommunitiesData AnalysesDementiaDiseaseDisparityDisparity populationDiverse WorkforceDoctor of PhilosophyEducationEducational StatusEducational workshopElderlyEnsureExperimental DesignsFloridaFosteringFundingGoalsHealthHealth ProfessionalHealthcareImpaired cognitionImpairmentInequalityInequityInstitutionLaboratoriesLaboratory ResearchLatinaLatinoLatinx populationMeasurableMentorsMentorshipMinority GroupsMissionNative AmericansNeurobiologyNot Hispanic or LatinoOutcomeParticipantPatient Self-ReportPersonal SatisfactionPopulationPostbaccalaureateProcessPublic HealthReduce health disparitiesResearchResearch ActivityResearch PersonnelResearch TrainingResourcesRiskSchoolsScientistSociologyStudentsTrainingTraining ProgramsTraining and EducationUnderrepresented MinorityUnited States National Institutes of HealthUniversitiesaging brainbridge to the baccalaureatecareerclinical trainingcomorbiditydisadvantaged backgroundexperiencehands on researchhealth disparityhealth inequalitiesimprovedinnovationinterestmatriculationmeetingsmemberminority health disparityminority undergraduateprogramsrandomized, clinical trialsrecruitresearch and developmentskillssummer researchundergraduate researchundergraduate student
项目摘要
Title: Networking and Expanding Undergraduate Research On the Neurobiology of Aging to Advance Diversity
(NEURON-Aging)
ABSTRACT: The goal of this NIA R25 proposal “Networking and Expanding Undergraduate Research On the
Neurobiology of Aging to Advance Diversity (NEURON-Aging)” is to expand the pool of researchers interested
in biomedical, behavioral, and clinical aspects of brain aging and Alzheimer’s disease and related dementias
(ADRDs) through undergraduate research activities that enhance diversity. Minority health disparities for
cognitive outcomes in advanced age are well documented, with older adults from minority groups being more
likely to self-report impairments and to develop dementia. Healthcare and research professions that are critical
for addressing clinical needs in diverse elderly populations, however, have inadequate representation from
diverse and disadvantaged groups. This is a significant barrier for mitigating these health inequities. Thus, there
is an urgent and unmet need to support educational pipeline programs that increase the diversity of the research
and clinical workforce focused on understanding and treating brain aging and ADRD to reduce minority health
disparities. The current proposal will expand the pool of undergraduate trainees interested in pursuing research
and clinical careers related to understanding and treating brain aging and ADRD with 3 Specific Aims. Aim 1 will
increase the participation of University of Florida (UF) underrepresented minority (URM) undergraduate students
conducting mentored research on the neurobiology of aging and ADRDs in NIH-funded laboratories and expand
their research network to facilitate an interest in brain aging. Aim 2 will increase the representation of URM
undergraduates from outside UF and non-Research I Institutions conducting mentored research in NIH-funded
laboratories examining brain aging and ADRDs. Finally, using institutional matching funds provided by Centers
and Institutes at the University of Florida, Aim 3 will increase the numbers of diverse students proceeding on to
top graduate programs focused on brain aging by proving 12-24 months of postbaccalaureate training as a bridge
to PhD training. The proposed education and research training program will have the following measurable
objectives: (1) NEURON-Aging students will develop an appreciation for brain aging and related diseases
through year-round mentorship and networking; (2) NEURON-Aging students will have an increased sense of
scientific efficacy through mentored, hands-on research training; 3) NEURON-Aging students will have an
enhanced understanding of experimental design and data interpretation in brain aging-research areas, (4)
NEURON-Aging students will develop professional communication skills by presenting their research locally and
nationally; (5) NEURON-Aging students will develop awareness of graduate and professional school program
application processes; and (6) The majority (>50%) of NEURON-Aging students will matriculate into graduate or
clinical training programs related to aging within two years of receiving their Bachelor's degree.
标题:建立和扩大关于衰老神经生物学的本科生研究,以促进多样性
(神经元老化)
摘要:NIA R25计划的目标是建立网络和扩展本科生的研究
《衰老促进多样性的神经生物学(神经元衰老)》是为了扩大研究人员的兴趣
在脑老化、阿尔茨海默病和相关痴呆的生物医学、行为和临床方面
(ADRD)通过促进多样性的本科生研究活动。少数族裔的健康差距
高龄时的认知结果被很好地记录下来,来自少数群体的老年人更多
可能会自我报告损伤,并患上痴呆症。至关重要的医疗保健和研究职业
然而,在满足不同老年人口的临床需求方面,来自
多元化和弱势群体。这是缓解这些健康不平等的一个重大障碍。因此,在那里
支持增加研究多样性的教育流水线项目是一个迫切而未得到满足的需求
临床工作人员专注于了解和治疗脑老化和ADRD,以减少少数人的健康
差距。目前的建议将扩大对从事研究感兴趣的本科生的人数
以及与认识和治疗脑老化和ADRD相关的临床职业生涯,有3个具体目标。目标1将
增加佛罗里达大学(UF)未被充分代表的少数民族(URM)本科生的参与率
在NIH资助的实验室中开展衰老和ADRDS的神经生物学指导研究并扩大
他们的研究网络促进了人们对大脑老化的兴趣。目标2将增加URM的代表性
来自密歇根大学和非研究I机构的本科生在美国国立卫生研究院资助的指导研究
检测大脑老化和ADRDS的实验室。最后,使用中心提供的机构匹配资金
和佛罗里达大学的学院,AIM 3将增加继续学习的不同学生的数量
顶尖的研究生课程专注于大脑老化,证明12-24个月的毕业后培训是一座桥梁
去参加博士培训。拟议的教育和研究培训计划将有以下可衡量的
目标:(1)神经元老化学生将培养对大脑老化和相关疾病的认识
通过全年的指导和网络;(2)神经元老化的学生将有更多的
通过有指导的、动手的研究培训提高科学效率;3)神经元老化的学生将有一个
增强对脑老化研究领域的实验设计和数据解释的理解,(4)
神经元老化的学生将通过在当地展示他们的研究和
全国范围内;(5)神经元老化学生将培养对研究生和专业学校课程的认识
申请程序;以及(6)大多数(50%)神经元老化学生将进入研究生或
在获得学士学位后两年内参加与老龄化有关的临床培训计划。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Jose Francisco Abisambra其他文献
Spatial mapping of the brain metabolome lipidome and glycome
大脑代谢组、脂质组和糖组的空间映射
- DOI:
10.1038/s41467-025-59487-7 - 发表时间:
2025-05-12 - 期刊:
- 影响因子:15.700
- 作者:
Harrison A. Clarke;Xin Ma;Cameron J. Shedlock;Terrymar Medina;Tara R. Hawkinson;Lei Wu;Roberto A. Ribas;Shannon Keohane;Sakthivel Ravi;Jennifer L. Bizon;Sara N. Burke;Jose Francisco Abisambra;Matthew E. Merritt;Boone M. Prentice;Craig W. Vander Kooi;Matthew S. Gentry;Li Chen;Ramon C. Sun - 通讯作者:
Ramon C. Sun
Jose Francisco Abisambra的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Jose Francisco Abisambra', 18)}}的其他基金
Contributions of tau-mediated translational dysregulation to pathogenesis and progression of fronto-temporal dementia
tau 介导的翻译失调对额颞叶痴呆发病机制和进展的影响
- 批准号:
10370091 - 财政年份:2022
- 资助金额:
$ 38.64万 - 项目类别:
Networking and Expanding Undergraduate Research on the Neurobiology of Aging to Advance Diversity
网络化和扩大衰老神经生物学本科研究以促进多样性
- 批准号:
10409946 - 财政年份:2022
- 资助金额:
$ 38.64万 - 项目类别:
Contributions of tau-mediated translational dysregulation to pathogenesis and progression of fronto-temporal dementia
tau 介导的翻译失调对额颞叶痴呆发病机制和进展的影响
- 批准号:
10554390 - 财政年份:2022
- 资助金额:
$ 38.64万 - 项目类别:
The molecular intersection of tau, TBI, and PERK
tau、TBI 和 PERK 的分子交集
- 批准号:
10317916 - 财政年份:2021
- 资助金额:
$ 38.64万 - 项目类别:
The molecular intersection of tau, TBI, and PERK
tau、TBI 和 PERK 的分子交集
- 批准号:
10489825 - 财政年份:2021
- 资助金额:
$ 38.64万 - 项目类别:
The molecular intersection of tau, TBI, and PERK
tau、TBI 和 PERK 的分子交集
- 批准号:
10625470 - 财政年份:2021
- 资助金额:
$ 38.64万 - 项目类别:
Identification of the Molecular Mechanisms Linking Alzheimer's Disease, PERK, and Mild Repetitive Head Injury
识别阿尔茨海默病、PERK 和轻度重复性头部损伤之间的关联分子机制
- 批准号:
9784437 - 财政年份:2020
- 资助金额:
$ 38.64万 - 项目类别:
Developing new conditional models to study tauopathy, amyloidosis, and their interaction
开发新的条件模型来研究 tau 蛋白病、淀粉样变性及其相互作用
- 批准号:
10458822 - 财政年份:2019
- 资助金额:
$ 38.64万 - 项目类别:
Developing new conditional models to study tauopathy, amyloidosis, and their interaction
开发新的条件模型来研究 tau 蛋白病、淀粉样变性及其相互作用
- 批准号:
9901854 - 财政年份:2019
- 资助金额:
$ 38.64万 - 项目类别:
PERK as a Central Mediator of Neurotoxicity in Tauopathies
PERK 作为 Tau蛋白病神经毒性的中心介质
- 批准号:
9783076 - 财政年份:2018
- 资助金额:
$ 38.64万 - 项目类别:
相似海外基金
Interplay between Aging and Tubulin Posttranslational Modifications
衰老与微管蛋白翻译后修饰之间的相互作用
- 批准号:
24K18114 - 财政年份:2024
- 资助金额:
$ 38.64万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
EMNANDI: Advanced Characterisation and Aging of Compostable Bioplastics for Automotive Applications
EMNANDI:汽车应用可堆肥生物塑料的高级表征和老化
- 批准号:
10089306 - 财政年份:2024
- 资助金额:
$ 38.64万 - 项目类别:
Collaborative R&D
The Canadian Brain Health and Cognitive Impairment in Aging Knowledge Mobilization Hub: Sharing Stories of Research
加拿大大脑健康和老龄化认知障碍知识动员中心:分享研究故事
- 批准号:
498288 - 财政年份:2024
- 资助金额:
$ 38.64万 - 项目类别:
Operating Grants
Baycrest Academy for Research and Education Summer Program in Aging (SPA): Strengthening research competencies, cultivating empathy, building interprofessional networks and skills, and fostering innovation among the next generation of healthcare workers t
Baycrest Academy for Research and Education Summer Program in Aging (SPA):加强研究能力,培养同理心,建立跨专业网络和技能,并促进下一代医疗保健工作者的创新
- 批准号:
498310 - 财政年份:2024
- 资助金额:
$ 38.64万 - 项目类别:
Operating Grants
関節リウマチ患者のSuccessful Agingに向けたフレイル予防対策の構築
类风湿性关节炎患者成功老龄化的衰弱预防措施的建立
- 批准号:
23K20339 - 财政年份:2024
- 资助金额:
$ 38.64万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Life course pathways in healthy aging and wellbeing
健康老龄化和福祉的生命历程路径
- 批准号:
2740736 - 财政年份:2024
- 资助金额:
$ 38.64万 - 项目类别:
Studentship
NSF PRFB FY 2023: Connecting physiological and cellular aging to individual quality in a long-lived free-living mammal.
NSF PRFB 2023 财年:将生理和细胞衰老与长寿自由生活哺乳动物的个体质量联系起来。
- 批准号:
2305890 - 财政年份:2024
- 资助金额:
$ 38.64万 - 项目类别:
Fellowship Award
I-Corps: Aging in Place with Artificial Intelligence-Powered Augmented Reality
I-Corps:利用人工智能驱动的增强现实实现原地老龄化
- 批准号:
2406592 - 财政年份:2024
- 资助金额:
$ 38.64万 - 项目类别:
Standard Grant
McGill-MOBILHUB: Mobilization Hub for Knowledge, Education, and Artificial Intelligence/Deep Learning on Brain Health and Cognitive Impairment in Aging.
McGill-MOBILHUB:脑健康和衰老认知障碍的知识、教育和人工智能/深度学习动员中心。
- 批准号:
498278 - 财政年份:2024
- 资助金额:
$ 38.64万 - 项目类别:
Operating Grants
Welfare Enhancing Fiscal and Monetary Policies for Aging Societies
促进老龄化社会福利的财政和货币政策
- 批准号:
24K04938 - 财政年份:2024
- 资助金额:
$ 38.64万 - 项目类别:
Grant-in-Aid for Scientific Research (C)