Neuronal membranes and connections in dementia: targets for intervention

痴呆症中的神经元膜和连接：干预目标

• 批准号: nhmrc : 1135720
• 负责人: Dr Lezanne Ooi
• 金额: $ 48.67万
• 依托单位: University of Wollongong
• 依托单位国家: 澳大利亚
• 项目类别: Targeted Calls
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/neuronal-membranes-connections-targets-intervention/1318270
• 关键词: Neuronal; membranes; connections; dementia; targets

This research aims to understand why some people with Mild Cognitive Impairment (MCI) progress to dementia, whilst others do not. The fact that some people’s cognitive abilities can improve provides an opportunity to study the mechanisms that protect their brain cells from the degeneration associated with dementia. Understanding the cellular changes will lead to therapies that can be tested in the lab for individuals.

这项研究旨在了解为什么有些轻度认知障碍（MCI）患者会发展为痴呆症，而另一些人则不会。事实上，一些人的认知能力可以提高，这为研究保护他们的脑细胞免受痴呆症相关退化的机制提供了一个机会。了解细胞的变化将导致可以在实验室对个体进行测试的治疗方法。