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IMMUNE MECHANISMS OF PROTECTION AGAINST MYCOBACTERIUM TUBERCULOSIS CENTER (IMPAC-TB)

IMMUNE MECHANISMS OF PROTECTION AGAINST MYCOBACTERIUM TUBERCULOSIS CENTER (IMPAC-TB)
预防结核分枝杆菌中心 (IMPAC-TB) 的免疫机制
批准号：
10027082
负责人：
SARAH FORTUNE
金额：
$1064.75万
依托单位：
HARVARD SCHOOL OF PUBLIC HEALTH
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
项目状态：
已结题
起止时间：
2019-09-30 至 2023-02-28
来源：
https://reporter.nih.gov/project-details/10027082
关键词：
Animal ModelAnimalsComputer SimulationGoalsHIVHumanImmuneImmune EvasionImmune TargetingImmune responseImmunityImmunologicsMusMycobacterium InfectionsMycobacterium tuberculosisResearch ActivityResearch PersonnelSIVSamplingTechnologyTestingTissuesTranslatingTuberculosisTuberculosis VaccinesVaccinescohortimprovedmultidisciplinarynon-tuberculosis mycobacterianonhuman primateprogramsresponse

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中文摘要
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英文摘要
The goal of this program is to establish an integrated multi-disciplinary team of highly collaborative investigators that will plan and conduct iterative, in-depth immunologic analyses of tissue-specific and systemic responses in small animals, non-human primates (NHPs), and humans to identify the key immune responses needed for protection against Mtb; identify immunologic targets that can be used to improve TB vaccine strategies. Other research activities under the program may include determining the impact of HIV/SIV and Nontuberculous Mycobacteria (NTM) infection(s) on relevant immune responses to Mtb infection or TB vaccines and identifying how bacterial immune evasion mechanisms subvert immune responses to Mtb.
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Establishing the Genetic Basis of Altered Drug Responses in Mycobacterium tuberculosis
  • 批准号：
    10595538
  • 项目类别：
  • 资助金额：
    $164.79万
  • 财政年份：
    2019
  • 负责人：
    SARAH FORTUNE
  • 依托单位：
    HARVARD MEDICAL SCHOOL
Establishing the Genetic Basis of Altered Drug Responses in Mycobacterium tuberculosis
  • 批准号：
    10390301
  • 项目类别：
  • 资助金额：
    $99.03万
  • 财政年份：
    2019
  • 负责人：
    SARAH FORTUNE
  • 依托单位：
    HARVARD MEDICAL SCHOOL
IMMUNE MECHANISMS OF PROTECTION AGAINST MYCOBACTERIUM TUBERCULOSIS CENTER (IMPAC-TB)
  • 批准号：
    10925119
  • 项目类别：
  • 资助金额：
    $874.28万
  • 财政年份：
    2019
  • 负责人：
    SARAH FORTUNE
  • 依托单位：
    HARVARD SCHOOL OF PUBLIC HEALTH
IMMUNE MECHANISMS OF PROTECTION AGAINST MYCOBACTERIUM TUBERCULOSIS CENTER (IMPAC-TB)
  • 批准号：
    10252739
  • 项目类别：
  • 资助金额：
    $819.12万
  • 财政年份：
    2019
  • 负责人：
    SARAH FORTUNE
  • 依托单位：
    HARVARD SCHOOL OF PUBLIC HEALTH
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