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Quantitative Immunological Assays to Assess HIV Antibodies and Vaccines

Quantitative Immunological Assays to Assess HIV Antibodies and Vaccines
评估 HIV 抗体和疫苗的定量免疫分析
批准号：
10021347
负责人：
John Mascola
金额：
$55.26万
依托单位：
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/10021347
关键词：
AnimalsAntibodiesBiological AssayGenesHIVHIV AntibodiesHIV vaccineHIV-1Immune responseImmunology procedureIndividualInfectionInfrastructureReagentRoleRunningSamplingSerumServicesStandardizationVaccinatedVaccine ResearchVaccinesVirusWorkmutantneutralizing antibody

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中文摘要
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英文摘要
We are a Core lab providing HIV antibody assay services to labs within the Vaccine Research Center, other intramural labs, and for collaborators around the world. Most of our work uses a standardized HIV-1 neutralization assay. We perform this assay on serum samples from vaccinated animals and HIV-infected individuals, and on antibodies isolated from such subjects. We also develop and maintain the reagents needed for these assays, including natural and mutant virus genes, stocks of viruses, and stocks of reference antibodies.
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Next Generation Development of Broadly Neutralizing HIV Antibodies for Prevention
HIV/AIDS Vaccine and Antibody Development
Pre-clinical Vaccine Development for Respiratory Viruses
Pre-clinical Vaccine and Antibody Development for Coronavirus Disease 2019 (COVID-19)
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