Engaging practices and communities in the development of interventions to promote HPV vaccine uptake

让实践和社区参与制定干预措施以促进 HPV 疫苗的接种

• 批准号: 10020919
• 负责人: Sean T O'Leary
• 金额: $ 16.91万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-19 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10020919
• 关键词: Address; Adolescent; Adoption; Area; Asthma; Cessation of life; Colorado; Communities; County; Development; Diagnosis; Evidence based intervention; Family; Geography; Goals; Guidelines; Health; Healthy People 2020; Human Papilloma Virus Vaccination; Human Papilloma Virus Vaccine; Human Papilloma Virus-Related Malignant Neoplasm; Human Papillomavirus; Individual; Intervention; Maintenance; Medical; Methodology; Methods; Morbidity - disease rate; Nurses; Parents; Participant; Patients; Primary Health Care; Process; Provider; Public Health; Recommendation; Reporting; Research; Research Personnel; Rural; Series; Testing; Translating; Translation Process; Translations; United States; Vaccination; Vaccines; Work; cardiovascular disorder prevention; colorectal cancer screening; cost; design; evidence based guidelines; experience; improved; innovation; member; novel; novel strategies; practice-based research network; preventable death; primary care setting; programs; recruit; sociodemographics; suburb; success; therapy design; therapy development; uptake

Project Summary The Healthy People 2020 report states a goal of 80% uptake of recommended vaccines among adolescents, including the human papillomavirus (HPV) vaccine. However, the rate of uptake of the HPV vaccine has been slow relative to the other vaccines in the adolescent series. The series completion of the HPV vaccine among adolescents is estimated at 48.6% in 2017, which will lead to excess morbidity and mortality from preventable, HPV-related cancers. Reasons for this are multifactorial and include factors at the level of the provider, primary care practice, patient and family, and the community. Previously developed interventions often focus only on one of these aspects and are often tested in academic settings where generalizability is difficult. Therefore, the development of interventions that are responsive to these multifactorial barriers in real-world settings is a priority area for research. This proposal will use the Boot Camp Translation (BCT) methodology to translate the guidelines and evidence for the HPV vaccination into a practice- and provider- level intervention designed to improve the acceptability of the HPV vaccine. As a community engagement approach, BCT is a 6-9 month iterative process that brings together multiple stakeholders to translate evidence-based guidelines and recommendations into locally relevant and meaningful messages, materials, and programs. BCT has demonstrated success in expediting the implementation of guidelines related to several health topics and our own pilot work demonstrates that this methodology is feasible and acceptable when applied to HPV vaccination. We propose to implement an HPV-focused BCT in three counties in Colorado with a below average county-level vaccination rate. Through an iterative, facilitated six-month process, each BCT group will design a multi-pronged intervention targeted at patients, parents, providers, and the general community to then be disseminated in the participating practices and communities over the subsequent six- month period. The strength of this approach is that BCT produces interventions that are dissemination-ready, incorporate both practice and community context, and improve the acceptability of evidence-based interventions to individual communities. The long-term goal is to develop a replicable approach and low-cost method of increasing HPV vaccine uptake that is easily adaptable to different settings and sociodemographic contexts. The Specific Aims of this project - Engaging practices and communities in the development of interventions to promote HPV vaccine uptake - are to (1) implement Boot Camp Translation in three geographically distinct Colorado communities to translate current evidence for HPV vaccination into locally relevant interventions designed to increase vaccine uptake; and (2) evaluate the impact of the BCT-designed intervention on practice-level HPV vaccine initiation rates. We hypothesize that the BCT-designed intervention will increase the rate of HPV vaccine initiation in the practices.

项目摘要 《健康人2020年的健康报告》指出，青少年中有80％的推荐疫苗吸收的目标， 包括人乳头瘤病毒（HPV）疫苗。但是，HPV疫苗的摄取率已经 相对于青少年系列中的其他疫苗慢。 HPV疫苗的系列完成 青少年在2017年估计为48.6％，这将导致可预防的发病率和死亡率过高， 与HPV相关的癌症。原因是多因素的原因，包括提供商级别的因素， 初级保健实践，患者和家庭以及社区。以前开发的干预措施通常集中 仅在这些方面之一，并且经常在困难的学术环境中进行测试。 因此，开发对现实世界中这些多因素障碍的干预措施的发展 设置是研究的优先领域。该建议将使用新兵训练营（BCT） 将HPV疫苗接种指南和证据转化为实践和提供者的方法论 水平干预旨在提高HPV疫苗的可接受性。作为社区参与 方法，BCT是一个为期6-9个月的迭代过程，汇集了多个利益相关者来翻译 基于证据的指南和建议，对本地相关和有意义的信息，材料以及 程序。 BCT在加快与几个有关的指南的实施方面取得了成功 健康主题和我们自己的飞行员工作表明，这种方法是可行的，可以接受 应用于HPV疫苗接种。我们建议在科罗拉多州的三个县实施以HPV为中心的BCT 低于平均水平的县级疫苗接种率。通过迭代，促进的六个月过程，每个BCT 小组将设计针对患者，父母，提供者和一般的多管齐下干预措施 在随后的六个中，社区将在参与实践和社区中传播 月期。这种方法的优势在于，BCT会产生干预措施 准备就绪，纳入实践和社区环境，并改善 对个别社区的基于证据的干预措施的可接受性。长期目标是 开发一种可复制的方法和低成本的方法来增加HPV疫苗的摄取，易于适应 不同的设置和社会人口统计环境。该项目的具体目标 - 参与实践 以及开发干预措施以促进HPV疫苗摄取的社区 - 至（1） 在三个地理上不同的科罗拉多州社区中实施新兵训练营的翻译，以翻译当前 HPV疫苗接种到旨在增加疫苗摄取的本地相关干预措施中的证据； （2） 评估BCT设计的干预措施对实践水平HPV疫苗起始率的影响。我们 假设BCT设计的干预措施将提高实践中HPV疫苗的起始率。