Technologies and Resources for Research Laboratories

研究实验室的技术和资源

• 批准号: 10027576
• 负责人: James T. Porter
• 金额: $ 23.16万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-02 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10027576
• 关键词: Address; Affect; Agreement; Behavioral Sciences; Centers of Research Excellence; Clinical; Clinical Investigator; Clinical Research; Communicable Diseases; Communities; Community Participation; Complement; Core Facility; Data; Development; Disasters; Disease; Educational workshop; Emerging Communicable Diseases; Ensure; Environment; Foundations; Funding; Goals; Health; Health Benefit; Health Sciences; Healthcare; Hispanics; Histopathology; Human; Improve Access; Infrastructure; Institution; Investments; Joints; Laboratories; Laboratory Research; Laboratory Technicians; Letters; Malignant Neoplasms; Measures; Medical; Molecular Biology; Outcome; Population; Positioning Attribute; Public Health; Publications; Puerto Rico; Research; Research Personnel; Research Project Grants; Research Support; Resources; Rest; Science; Services; Technical Expertise; Technology; Time; Training; Training Support; Training and Education; Translating; Translational Research; United States; United States National Institutes of Health; Universities; Update; cardiometabolism; improved; institutional capacity; investigator training; laboratory equipment; laboratory experience; medical schools; medically underserved; outreach; recruit; research facility; skills; stem; success; translational scientist

Capacity building is necessary for supporting research on issues affecting human health in under-resourced communities such as Puerto Rico. The Technologies and Resources for Research Laboratories Core (TRRCL) is a component of the Hispanic Alliance for Clinical and Translational Research (the Alliance) composed of the University of Puerto Rico Medical Sciences Campus (UPR-MSC), the Ponce Medical School Foundation (PMSF), and the Universidad Central del Caribe (UCC). TRRCL services to clinical and translational investigators in Puerto Rico has increased steadily from 2014 until 2019. Under the newly conceived Alliance, the TRRCL team proposes to continue developing the capacity of TRRCL to fulfill the needs of clinical and translational investigators who require specialized laboratory equipment and services to conduct their research. It is expected that continuous access to cutting-edge technologies and laboratory resources facilitated by the TRRCL will motivate more investigators to conduct clinical and translational research successfully and increase the institutional capacity to address health issues impacting underserved Hispanic populations in Puerto Rico and the rest of the US. The TRRCL´s main goal for this project is to improve shared research facilities for investigators, and to improve access for investigators to these facilities. The objective of TRRCL is to ensure that investigators that require laboratory space and technical support receive access to core laboratory services thereby allowing for the timely completion and publication of their research projects. The central hypothesis is that the TRRCL will catalyze an increase in active clinical and translational research projects in the Alliance institutions. The TRRCL will achieve this by: 1) supporting the training of researchers in the Alliance institutions and increasing researchers´ access to TRRCL cores and highly trained staff; 2) providing investigators the technical expertise and infrastructure they need to produce reliable data that is of publication quality, and; 3) enhancing the impact and outreach of the TRRCLby establishing collaborative agreements with other institutions and by participation in community engagement activities. As the TRRCL usage increases, the team expects to satisfy the increased demand by collaborating INBRE and COBRE research cores in Puerto Rico and in other IDeA states. TRRCLwill complement this support and accelerate progress on research projects that will translate to health benefits for the Puerto Rico population and underserved Hispanic/Latino populations across the nation, and will result in a more competitive biomedical workforce in Puerto Rico supported by state-of-the-art research f ac ilities.

能力建设对于支持资源不足国家研究影响人类健康的问题是必要的。 例如波多黎各。研究实验室核心技术和资源（TRRCL） 是西班牙裔临床和转化研究联盟（联盟）的一个组成部分， 波多黎各大学医学院（UPR-MSC），庞塞医学院基金会 （PMSF）和加勒比中央大学（UCC）。TRRCL为临床和翻译服务 从2014年到2019年，波多黎各的调查人员人数稳步增加。根据新构想的联盟， TRRCL团队建议继续发展TRRCL的能力，以满足临床和 翻译研究人员需要专门的实验室设备和服务来进行研究。 预计，持续获得尖端技术和实验室资源的便利， TRRCL将激励更多的研究者成功开展临床和转化研究， 解决影响波多黎各服务不足的西班牙裔人口的卫生问题的机构能力 和美国其他地区。该项目的主要目标是改善共享研究设施， 调查人员，并改善调查人员进入这些设施。TRRCL的目标是确保 需要实验室空间和技术支持的调查人员可以获得核心实验室服务 从而使他们的研究项目能够及时完成和发表。核心假设是 TRRCL将促进联盟中活跃的临床和转化研究项目的增加 机构职能体系TRRCL将通过以下方式实现这一目标：1）支持联盟机构的研究人员培训 增加研究人员获得TRRCL核心和训练有素的工作人员的机会; 2）为研究人员提供 他们需要技术专门知识和基础设施，以产生具有出版质量的可靠数据，以及; 3） 通过与其他机构达成合作协议，增强TRRCL的影响力和覆盖面 以及参与社区活动。随着TRRCL使用量的增加，该团队预计， 通过在波多黎各和其他地区合作INBRE和COBRE研究核心，满足不断增长的需求 IDEA表示。TRRCL将补充这一支持，并加快研究项目的进展， 为全国波多黎各人口和服务不足的西班牙裔/拉丁裔人口提供健康福利， 并将在最先进的研究支持下，在波多黎各形成更具竞争力的生物医学劳动力 设施。