DETECTING EMERGING VECTOR-BORNE ZOONOTIC PATHOGENS IN INDONESIA

描述（由申请方提供）：印度尼西亚很可能是研究新出现的人畜共患病病原体（尤其是虫媒病毒）的重要场所。在过去十年中，许多虫媒病毒的爆发表明，节肢动物传播的病原体仍然是重大的公共和动物健康威胁。这些疫情在全球范围内发生，并不局限于热带或发展中国家，因为人员和货物可以在几天内转移到世界任何地方。幸运的是，科学研究，包括快速检测这一多样化病原体的进展，也在不断取得进展。虽然虫媒病毒可能会不断出现和重新出现，但改进的科学技术和方法有望使未来每一次流行病发生的可能性降低。我们对万隆存档标本的研究将是对印度尼西亚新出现病毒的首次系统调查，采用金标准测定法估计这些病毒的传播规模。

DESCRIPTION (provided by applicant): Indonesia is most likely an important place for the study of emerging zoonotic pathogens, especially arboviruses. Numerous arboviral outbreaks during the past decade have demonstrated that arthropod-borne pathogens continue to be significant public and animal health threats. These outbreaks have occurred globally and have not been limited to tropical or developing countries, as people and goods can be moved anywhere in the world within days. Fortunately, scientific research, including advances in rapid detection of this diverse group of pathogens, has also been progressing. While arboviruses are likely to continually emerge and re-emerge, improved scientific technologies and approaches will hopefully make each future epidemic less likely to occur. Our study with archived specimens in Bandung would be the first systemic survey on emerging viruses in Indonesia with gold standard assays to estimate the magnitude of circulation of these viruses.