6th Annual Midwest Tumor Microenvironment Meeting

项目摘要 我们要求为在华盛顿大学举行的中西部肿瘤微环境会议提供部分资金 堪萨斯州堪萨斯城的堪萨斯医疗中心，2020年5月18日至20日。会议于2015年开幕，目前 中西部地区唯一一次肿瘤微环境会议。这次会议已经确立了自己的地位 高度重视对肿瘤微环境跨学科科学领域的贡献，重点是 免疫系统和间质在肿瘤生长和进展中的作用。2020年会议联合主办方 是Shrikant Anant博士和Sufi M.Thomas博士。会议将召集18位演讲者和多达200人 参与者。将特别努力招募少数族裔参与者。会议还将提供一个论坛 供处于职业生涯早期阶段的实习生和科学家展示他们的数据并与其他人在 田野。来自冷泉港实验室的大卫·图文森博士是探索 恶性生物学，从而确定新的诊断和治疗策略将介绍他最近的工作 在病人衍生的器官模型上。此外，匹兹堡大学医学院的特蕾莎·怀特赛德博士 研究免疫功能在肿瘤发生中的作用的中心将介绍她最近在基质方面的工作-- 衍生的外切体及其在肿瘤发生中的作用。演讲的主题将是多个- 学科包括研究与肿瘤-间质相互作用相关问题的新技术，以及 影响肿瘤发生的各种细胞和细胞外基质因素。除了特邀演讲者外，受训人员 年轻的调查人员将有机会在口头陈述会议上发言。此外，还将有 作为两个张贴海报的会议，这将允许所有参与者为会议做出贡献。机遇将特别 提供给您的调查人员、女性和少数族裔与讲师和代表进行互动 来自美国国家癌症研究所肿瘤微环境项目。通过R13机制提供的资金是 要求支付青年调查员和受训人员参加会议的费用。我们期待着 研究肿瘤微环境的各个方面的研究人员将培养新的合作和 学员将根据本次会议的网络机会确定新的导师。

Project Summary We request partial funding for the Midwest Tumor Microenvironment Meeting to be held at the University of Kansas Medical Center in Kansas City, KS on May 18-20, 2020. The meeting was inaugurated in 2015 and is the only meeting on tumor microenvironment in the Midwest region. This meeting has established itself as a highly valued contribution to the interdisciplinary scientific field of the tumor microenvironment, with focus on the role of immune system and the stroma in cancer growth and progression. The 2020 conference co-organizers are Shrikant Anant, Ph.D. and Sufi M. Thomas, Ph.D. The meeting will convene 18 speakers and up to 200 participants. A special effort will be made to recruit minority participants. The meeting will also provide a forum for trainees and scientists who are in early stages of their career to present their data and network with others in the field. Dr. David Tuveson from the Cold Spring Harbor Laboratory, an expert in exploring the fundamental biology of malignancy and thereby identify new diagnostic and treatment strategies will present his recent work on patient-derived organoid models. In addition, Dr. Theresa Whiteside from the University of Pittsburgh Medical Center, who investigates the role of the immune function in tumorigenesis will present her recent work on stroma- derived exosomes and their role in tumorigenesis in her keynote address. Topics for presentation will be multi- disciplinary including novel technologies to study issues related to tumor-stroma interactions, as well as the various cellular and extracellular matrix factors affecting tumorigenesis. In addition to invited speakers, trainees and young investigators will have the opportunity to present in oral presentation sessions. In addition, there will be two poster sessions, which will allow all participants to contribute to the meeting. Opportunities will especially be given to your investigators, women, and minorities to interact with the presenting faculty and representatives from the National Cancer Institute Tumor Microenvironment Program. Funding through this R13 mechanism is requested to defray the cost of participating in the meeting for young investigators and trainees. We expect that researchers dealing with various aspects of the tumor microenvironment will cultivate new collaborations and the trainees will identify new mentors as a result of the networking opportunity from this meeting.