6th Annual Midwest Tumor Microenvironment Meeting

项目摘要 我们请求为将在密歇根大学举行的中西部肿瘤微环境会议提供部分资金。 2020年5月18日至20日，堪萨斯州堪萨斯城的堪萨斯医疗中心。该会议于2015年开幕， 中西部地区唯一一次关于肿瘤微环境的会议。这次会议已成为 高度重视对肿瘤微环境跨学科科学领域的贡献，重点是 免疫系统和间质在癌症生长和进展中的作用。2020年会议协办单位 是Shrikant Anant，博士苏菲M。托马斯博士会议将召集18名发言人和最多200人 参与者将特别努力征聘少数族裔与会者。会议还将提供论坛， 为处于职业生涯早期阶段的学员和科学家提供数据，并与其他人建立联系， 外地来自冷泉港实验室的大卫·图维森博士是探索 恶性肿瘤生物学，从而确定新的诊断和治疗策略将介绍他最近的工作 病人衍生的类器官模型。此外，匹兹堡大学医学院的Theresa Whiteside博士 研究免疫功能在肿瘤发生中的作用的中心将介绍她最近在基质方面的工作， 衍生的外泌体及其在肿瘤发生中的作用。演讲的主题将是多方面的- 学科，包括新的技术，以研究与肿瘤间质相互作用，以及 影响肿瘤发生的各种细胞和细胞外基质因子。除了受邀演讲者， 年轻的研究人员将有机会在口头报告会上发言。此外还将 将举办两次海报会议，使所有与会者都能为会议作出贡献。机会将特别 让你的研究人员、妇女和少数民族与在场的教师和代表互动 来自国家癌症研究所肿瘤微环境项目。通过这一R13机制提供的资金是 要求支付年轻调查员和受训人员参加会议的费用。我们预计 处理肿瘤微环境各个方面的研究人员将培养新的合作， 学员们将通过这次会议提供的建立联系的机会确定新的导师。

Project Summary We request partial funding for the Midwest Tumor Microenvironment Meeting to be held at the University of Kansas Medical Center in Kansas City, KS on May 18-20, 2020. The meeting was inaugurated in 2015 and is the only meeting on tumor microenvironment in the Midwest region. This meeting has established itself as a highly valued contribution to the interdisciplinary scientific field of the tumor microenvironment, with focus on the role of immune system and the stroma in cancer growth and progression. The 2020 conference co-organizers are Shrikant Anant, Ph.D. and Sufi M. Thomas, Ph.D. The meeting will convene 18 speakers and up to 200 participants. A special effort will be made to recruit minority participants. The meeting will also provide a forum for trainees and scientists who are in early stages of their career to present their data and network with others in the field. Dr. David Tuveson from the Cold Spring Harbor Laboratory, an expert in exploring the fundamental biology of malignancy and thereby identify new diagnostic and treatment strategies will present his recent work on patient-derived organoid models. In addition, Dr. Theresa Whiteside from the University of Pittsburgh Medical Center, who investigates the role of the immune function in tumorigenesis will present her recent work on stroma- derived exosomes and their role in tumorigenesis in her keynote address. Topics for presentation will be multi- disciplinary including novel technologies to study issues related to tumor-stroma interactions, as well as the various cellular and extracellular matrix factors affecting tumorigenesis. In addition to invited speakers, trainees and young investigators will have the opportunity to present in oral presentation sessions. In addition, there will be two poster sessions, which will allow all participants to contribute to the meeting. Opportunities will especially be given to your investigators, women, and minorities to interact with the presenting faculty and representatives from the National Cancer Institute Tumor Microenvironment Program. Funding through this R13 mechanism is requested to defray the cost of participating in the meeting for young investigators and trainees. We expect that researchers dealing with various aspects of the tumor microenvironment will cultivate new collaborations and the trainees will identify new mentors as a result of the networking opportunity from this meeting.