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Roadmap for America's Cancer Explorers for the 21st Century (Race 21)

21 世纪美国癌症探索者路线图（第 21 场比赛）

基本信息

批准号：
10023708
负责人：
Lalita A. Shevde
金额：
$ 41.79万
依托单位：
UNIVERSITY OF ALABAMA AT BIRMINGHAM
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-09-03 至 2025-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10023708
关键词：
Abbreviations Adult Advanced Malignant Neoplasm Africa African American Alabama American Americas Area Awareness Biology Cancer Biology Cancer Death Rates Cancer Etiology Clinical Trials Communication Community Outreach Comprehensive Cancer Center Development Early Diagnosis Early treatment Education Exposure to Family Fellowship Foundations Future Generations General Population Goals Health High School Faculty High School Student Individual Institutes Internships Knowledge Mainstreaming Malignant Neoplasms Mentors Methods Minority Modeling Morbidity - disease rate NCI Center for Cancer Research Next Generation Science Standards Parents Pathway interactions Phase Positioning Attribute Prevention Program Development Race Research Research Personnel Research Training Resources Schools Science Science, Technology, Engineering and Mathematics Science, Technology, Engineering and Mathematics Education Secondary Schools Students Teacher Professional Development Testing Text Training Underrepresented Populations Underrepresented Students Universities Work Youth anticancer research base cancer health disparity career cohort community center experience high school improved innovation interest male minority communities minority student mortality next generation outreach programs science teacher skills summer internship summer research teacher twelfth grade undergraduate student underrepresented minority student university student

项目摘要

Roadmap for America’s Cancer Explorers for the 21st Century (RACE21) is an interdisciplinary program to develop a pipeline to a diverse 21st century cancer research workforce. Cancer is a primary cause of adult mortalities in the US, despite excellent advances in understanding cancer biology and innovative treatments. In Alabama, cancer is the 2nd highest cause of mortality, and cancer death rates are almost double in Alabama’s African-American (compared to White) males. One of the underlying causes of this anomaly is the lack of communication about cancer among Africa-Americans, especially within families. Also, relatively few African-American youth are seeking careers in cancer research, largely due to very little exposure to cancer biology in most of their secondary schools and their teachers’ lack of cancer biology training. Further, few informal programs excite students about careers in cancer biology. RACE21 will build an innovative and effective pipeline to cancer research careers, especially for students underrepresented in cancer research (URM) by building on 5-basic foundations: 1) The University of Alabama at Birmingham’s (UAB) outstanding O’Neal Comprehensive Cancer Center, 2) Over 200 cancer researchers, eager to mentor high school and college students to become the next generation of cancer researchers, 3) development of an innovative Undergraduate Cancer Biology Major, 4) the Center for Community OutReach Development (CORD), which will train high school biology teachers in cancer research and introduce advanced high school students to cancer research in both formal and informal settings and 5) training in communication about cancer. RACE21 employs successful methods developed at UAB, and uses them to advance cancer biology education. The pipeline starts with high school students being introduced to cancer biology through state-of-the-art experiences in the Summer Science Institute (10 URM rising seniors will be Summer Research Interns) and experiences at the GENEius lab. RACE21 will also provide intense cancer biology training to high school teachers via an annual 3-week BioTeach-Cancer training. RACE21 students (>80% URM) entering UAB’s new Cancer Biology Major will complete a paid summer internship in cancer research in their rising year 1 and 2, and in year 3 and 4 they will receive fellowships as cancer researchers. Each year 10 RACE21 students will complete the undergraduate major, with most continuing to graduate school in cancer research related areas. The Intellectual Merit of RACE21 will be in testing a pipeline that leads to increased minorities in cancer biology careers. The Broader Impacts will annually educate about 6,000 minority students, families and the public about cancer biology and launch the cancer research careers of >40 minority students.

世纪美国癌症探索者路线图（RACE 21）是一个跨学科的该计划旨在为多元化的21世纪世纪癌症研究人员提供一个渠道。癌症是尽管在理解癌症方面取得了很大进展，生物学和创新疗法。在亚拉巴马，癌症是第二大死亡原因，在亚拉巴马的非洲裔美国男性中，癌症死亡率几乎是白色男性的两倍。这种异常现象的根本原因之一是缺乏对癌症的沟通，非裔美国人，尤其是在家庭中。此外，相对较少的非洲裔美国青年在癌症研究中寻找职业，主要是由于在大多数情况下很少接触癌症生物学，他们的中学和他们的教师缺乏癌症生物学培训。此外，少数非正式项目激发学生对癌症生物学职业的兴趣。RACE 21将建立一个创新和癌症研究职业的有效渠道，特别是对于癌症代表性不足的学生研究（URM）建立在5个基本基础上：1）伯明翰的亚拉巴马大学 (UAB)杰出的奥尼尔综合癌症中心，2）200多名癌症研究人员，渴望指导高中生和大学生成为下一代癌症患者研究人员，3）创新的本科癌症生物学专业的发展，4）中心社区外展发展（CORD），这将培训高中生物教师，癌症研究，并介绍先进的高中生癌症研究在两个正式的和非正式的环境和5）关于癌症的沟通培训。RACE 21成功雇用在UAB开发的方法，并使用它们来推进癌症生物学教育。管道从高中生开始，通过最先进的技术，在夏季科学研究所的经验（10 URM上升老年人将夏季研究实习生）和GENEius实验室的经验。RACE 21还将提供强烈的癌症生物学通过每年为期3周的BioTeach-Cancer培训，对高中教师进行培训。RACE 21学生（>80% URM）进入UAB的新癌症生物学专业将完成带薪暑期实习在癌症研究在他们上升的第一年和第二年，并在第三年和第四年，他们将获得奖学金，癌症研究者每年10名RACE 21学生将完成本科专业，大多数继续在癌症研究相关领域的研究生院。的智力价值 RACE 21将测试一个管道，导致癌症生物学职业中的少数群体增加。更广泛的影响每年将教育约6,000名少数民族学生，家庭和公众关于癌症生物学，并启动了40多名少数民族学生的癌症研究事业。