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Roadmap for America's Cancer Explorers for the 21st Century (Race 21)

21 世纪美国癌症探索者路线图（第 21 场比赛）

基本信息

批准号：
10252847
负责人：
Lalita A. Shevde
金额：
$ 41.79万
依托单位：
UNIVERSITY OF ALABAMA AT BIRMINGHAM
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-09-03 至 2025-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10252847
关键词：
Abbreviations Adult Advanced Malignant Neoplasm Africa African American Alabama American Americas Area Awareness Biology Cancer Biology Cancer Death Rates Cancer Etiology Clinical Trials Communication Community Outreach Comprehensive Cancer Center Development Early Diagnosis Early treatment Education Exposure to Family Fellowship Foundations Future Generations General Population Goals Health High School Faculty High School Student Individual Institutes Internships Knowledge Mainstreaming Malignant Neoplasms Mentors Methods Minority Modeling Morbidity - disease rate NCI Center for Cancer Research Next Generation Science Standards Parents Pathway interactions Phase Positioning Attribute Prevention Program Development Race Research Research Personnel Research Training Resources Schools Science Science, Technology, Engineering and Mathematics Science, Technology, Engineering and Mathematics Education Secondary Schools Students Teacher Professional Development Testing Text Training Underrepresented Populations Underrepresented Students Universities Work Youth anticancer research base cancer health disparity career cohort community center experience high school improved innovation interest male minority communities minority student mortality next generation outreach programs science teacher skills summer internship summer research teacher twelfth grade undergraduate student underrepresented minority student university student

项目摘要

Roadmap for America’s Cancer Explorers for the 21st Century (RACE21) is an interdisciplinary program to develop a pipeline to a diverse 21st century cancer research workforce. Cancer is a primary cause of adult mortalities in the US, despite excellent advances in understanding cancer biology and innovative treatments. In Alabama, cancer is the 2nd highest cause of mortality, and cancer death rates are almost double in Alabama’s African-American (compared to White) males. One of the underlying causes of this anomaly is the lack of communication about cancer among Africa-Americans, especially within families. Also, relatively few African-American youth are seeking careers in cancer research, largely due to very little exposure to cancer biology in most of their secondary schools and their teachers’ lack of cancer biology training. Further, few informal programs excite students about careers in cancer biology. RACE21 will build an innovative and effective pipeline to cancer research careers, especially for students underrepresented in cancer research (URM) by building on 5-basic foundations: 1) The University of Alabama at Birmingham’s (UAB) outstanding O’Neal Comprehensive Cancer Center, 2) Over 200 cancer researchers, eager to mentor high school and college students to become the next generation of cancer researchers, 3) development of an innovative Undergraduate Cancer Biology Major, 4) the Center for Community OutReach Development (CORD), which will train high school biology teachers in cancer research and introduce advanced high school students to cancer research in both formal and informal settings and 5) training in communication about cancer. RACE21 employs successful methods developed at UAB, and uses them to advance cancer biology education. The pipeline starts with high school students being introduced to cancer biology through state-of-the-art experiences in the Summer Science Institute (10 URM rising seniors will be Summer Research Interns) and experiences at the GENEius lab. RACE21 will also provide intense cancer biology training to high school teachers via an annual 3-week BioTeach-Cancer training. RACE21 students (>80% URM) entering UAB’s new Cancer Biology Major will complete a paid summer internship in cancer research in their rising year 1 and 2, and in year 3 and 4 they will receive fellowships as cancer researchers. Each year 10 RACE21 students will complete the undergraduate major, with most continuing to graduate school in cancer research related areas. The Intellectual Merit of RACE21 will be in testing a pipeline that leads to increased minorities in cancer biology careers. The Broader Impacts will annually educate about 6,000 minority students, families and the public about cancer biology and launch the cancer research careers of >40 minority students.

21世纪美国癌症探索者路线图(Race21)是一个跨学科的该计划旨在开发一条通往21世纪多元化癌症研究队伍的管道。癌症是一种美国成人死亡的主要原因，尽管对癌症的理解取得了很大进展生物学和创新疗法。在阿拉巴马州，癌症是第二大死亡原因，阿拉巴马州非裔美国人(与白人相比)的癌症死亡率几乎是白人的两倍。这种反常现象的根本原因之一是人们之间缺乏关于癌症的沟通非洲裔美国人，特别是在家庭内部。此外，相对较少的非裔美国青年是寻求癌症研究的职业，主要是因为大多数人对癌症生物学的接触很少由于他们的中学和教师缺乏癌症生物学培训。此外，很少有非正式的这些项目让学生们对癌症生物学的职业感到兴奋。Race21将构建一个创新和通往癌症研究事业的有效渠道，特别是对癌症研究人数不足的学生研究(URM)建立在5个基本基础上：1)阿拉巴马大学伯明翰分校 (UAB)杰出的奥尼尔综合癌症中心，2)200多名癌症研究人员，渴望辅导高中生和大学生成为下一代癌症研究人员，3)创新型本科肿瘤生物学专业的发展，4)中心社区外展发展(CORD)，它将培训高中生物教师癌症研究和向高中生介绍癌症研究都是正规的以及非正式的环境和5)关于癌症的沟通培训。Race21使用成功方法在UAB发展，并利用它们来推进癌症生物学教育。这条管道首先通过最先进的技术向高中生介绍癌症生物学在暑期科学学院的经历(10名URM高年级学生将进行暑期研究实习生)和在GENEIUS实验室的经验。Race21还将提供强烈的癌症生物学通过每年3周的生物教学-癌症培训对高中教师进行培训。21届学生比赛 (&gt；80%URM)进入UAB新的癌症生物学专业将完成带薪暑期实习在他们第一年和第二年的癌症研究中，在第三年和第四年，他们将获得奖学金癌症研究人员。每年将有10名Race21学生完成本科专业，大多数人继续在癌症研究相关领域研究生院学习。在智力方面的功绩 Race21将测试一条管道，该管道将导致癌症生物学职业生涯中少数族裔的增加。更广泛的影响每年将教育大约6,000名少数民族学生、家庭和公众关于癌症生物学，并启动&gt；40名少数民族学生的癌症研究事业。