Roadmap for America's Cancer Explorers for the 21st Century (Race 21)

21 世纪美国癌症探索者路线图（第 21 场比赛）

• 批准号: 10252847
• 负责人: Lalita A. Shevde
• 金额: $ 41.79万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-03 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10252847
• 关键词: Abbreviations; Adult; Advanced Malignant Neoplasm; Africa; African American; Alabama; American; Americas; Area; Awareness; Biology; Cancer Biology; Cancer Death Rates; Cancer Etiology; Clinical Trials; Communication; Community Outreach; Comprehensive Cancer Center; Development; Early Diagnosis; Early treatment; Education; Exposure to; Family; Fellowship; Foundations; Future Generations; General Population; Goals; Health; High School Faculty; High School Student; Individual; Institutes; Internships; Knowledge; Mainstreaming; Malignant Neoplasms; Mentors; Methods; Minority; Modeling; Morbidity - disease rate; NCI Center for Cancer Research; Next Generation Science Standards; Parents; Pathway interactions; Phase; Positioning Attribute; Prevention; Program Development; Race; Research; Research Personnel; Research Training; Resources; Schools; Science; Science, Technology, Engineering and Mathematics; Science, Technology, Engineering and Mathematics Education; Secondary Schools; Students; Teacher Professional Development; Testing; Text; Training; Underrepresented Populations; Underrepresented Students; Universities; Work; Youth; anticancer research; base; cancer health disparity; career; cohort; community center; experience; high school; improved; innovation; interest; male; minority communities; minority student; mortality; next generation; outreach; programs; science teacher; skills; summer internship; summer research; teacher; twelfth grade; undergraduate student; underrepresented minority student; university student

Roadmap for America’s Cancer Explorers for the 21st Century (RACE21) is an interdisciplinary program to develop a pipeline to a diverse 21st century cancer research workforce. Cancer is a primary cause of adult mortalities in the US, despite excellent advances in understanding cancer biology and innovative treatments. In Alabama, cancer is the 2nd highest cause of mortality, and cancer death rates are almost double in Alabama’s African-American (compared to White) males. One of the underlying causes of this anomaly is the lack of communication about cancer among Africa-Americans, especially within families. Also, relatively few African-American youth are seeking careers in cancer research, largely due to very little exposure to cancer biology in most of their secondary schools and their teachers’ lack of cancer biology training. Further, few informal programs excite students about careers in cancer biology. RACE21 will build an innovative and effective pipeline to cancer research careers, especially for students underrepresented in cancer research (URM) by building on 5-basic foundations: 1) The University of Alabama at Birmingham’s (UAB) outstanding O’Neal Comprehensive Cancer Center, 2) Over 200 cancer researchers, eager to mentor high school and college students to become the next generation of cancer researchers, 3) development of an innovative Undergraduate Cancer Biology Major, 4) the Center for Community OutReach Development (CORD), which will train high school biology teachers in cancer research and introduce advanced high school students to cancer research in both formal and informal settings and 5) training in communication about cancer. RACE21 employs successful methods developed at UAB, and uses them to advance cancer biology education. The pipeline starts with high school students being introduced to cancer biology through state-of-the-art experiences in the Summer Science Institute (10 URM rising seniors will be Summer Research Interns) and experiences at the GENEius lab. RACE21 will also provide intense cancer biology training to high school teachers via an annual 3-week BioTeach-Cancer training. RACE21 students (>80% URM) entering UAB’s new Cancer Biology Major will complete a paid summer internship in cancer research in their rising year 1 and 2, and in year 3 and 4 they will receive fellowships as cancer researchers. Each year 10 RACE21 students will complete the undergraduate major, with most continuing to graduate school in cancer research related areas. The Intellectual Merit of RACE21 will be in testing a pipeline that leads to increased minorities in cancer biology careers. The Broader Impacts will annually educate about 6,000 minority students, families and the public about cancer biology and launch the cancer research careers of >40 minority students.

21世纪的美国癌症探险家（Race21）是跨学科的路线图 为21世纪潜水员研究劳动力发展提供管道的计划。癌症是 美国成人死亡率的主要原因，莫德斯（Dospite）在理解癌症方面取得了巨大进步 生物学和创新治疗。在阿拉巴马州，癌症是死亡率的第二高原因， 在阿拉巴马州的非裔美国人（与白人）男性相比，癌症死亡率几乎是两倍。 这种异常的根本原因之一是缺乏关于癌症的交流 非洲裔美国人，尤其是家庭内部。而且，相对较少的非洲裔美国人是 在癌症研究中寻求职业，这在很大程度上是由于大多数癌症生物学的接触很少 他们的中学和老师缺乏癌症生物学培训。此外，很少有非正式 节目激发了学生对癌症生物学的职业。 Race21将建立创新的 癌症研究职业的有效饲料，尤其是对于癌症中代表性不足的学生 研究（URM）通过在5个基础基础上建造：1）阿拉巴马大学伯明翰大学 （UAB）杰出的O'Neal综合癌症中心，2）超过200多个癌症研究人员， 渴望精神高中和大学生成为下一代癌症 研究人员，3）开发创新的本科癌症生物学专业，4）中心 对于社区外展发展（CORD），将培训高中生物学教师 癌症研究并将高级高中生介绍给两者的癌症研究 以及非正式的环境和5）有关癌症的沟通培训。 Race21员工成功 UAB开发的方法，并使用它们来推进癌症生物学教育。管道 首先，高中生通过最先进的 夏季科学学院的经验（10名URM崛起的老年人将是夏季研究 实习生）和Geneius实验室的经验。 Race21还将提供强烈的癌症生物学 通过一年一度的3周生物教学培训对高中教师进行培训。 Race21学生 （> 80％URM）进入UAB的新癌症生物学专业将完成带薪暑期实习 在上升的1年级和2年级的癌症研究中，在第3年和4年中，他们将获得奖学金 癌症研究人员。每年有10名Race21学生将完成本科专业 大多数继续在与癌症研究相关领域的研究生院。智力优点 Race21将在测试一条管道，从而导致癌症生物学职业的少数群体增加。 更广泛的影响将每年对约6,000名少数学生，家庭和公众进行教育 关于癌症生物学并启动了40名少数族裔学生的癌症研究职业。