Development of a Telehealth Screener and Assessment for Infants at-risk for ASD in Diverse Communities.

为不同社区中有自闭症谱系障碍风险的婴儿开发远程医疗筛查和评估。

• 批准号: 10024067
• 负责人: Meagan Ruth Talbott
• 金额: $ 19.63万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-30 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10024067
• 关键词: Address; Age; Age-Months; Behavioral; Benchmarking; Biological Markers; Caregivers; Collection; Communication; Communities; Country; Data; Development; Diagnostic; Discipline; Early identification; Eligibility Determination; Ensure; Evaluation; Family; Feasibility Studies; Feedback; Funding; Future; Geography; Goals; Growth; Health Services Accessibility; Home environment; Infant; Infant Behavior; Infant Development; Intervention; Intervention Trial; Life; Measures; Mediating; Methods; Modeling; Monitor; Neurobiology; Outcome; Parents; Phase; Protocols documentation; Publications; Randomized; Reporting; Research Personnel; Resources; Risk; Rural; Sampling; Scientist; Screening procedure; Services; Siblings; Symptoms; System; Testing; Training; Travel; Universities; Validity and Reliability; Visit; Vulnerable Populations; Wait Time; Waiting Lists; aged; autism spectrum disorder; autistic children; base; community based participatory research; community setting; control trial; cost; cost effective; disorder risk; field study; high risk infant; high risk population; improved; longitudinal analysis; meetings; prospective; recruit; routine screening; satisfaction; screening; social communication; standardize measure; telehealth

Project Summary The overall goal of this proposal is to develop a telehealth procedure for screening infants 6-12 months of age for early autism spectrum disorder (ASD) symptoms. While some promising biomarkers have been identified for infants in this age range, neurobiological methods are not feasible for widespread implementation, especially in rural and low-resource service systems. Families with early concerns are faced with long waitlists for an evaluation and often must travel long distances for evaluations at centers with appropriate expertise. Telehealth has been used as a cost-effective approach for increasing access to services across many disciplines, and there is some initial use of telehealth treatment approaches in ASD, but there are currently no established telehealth screening procedures to screen infants for ASD. Developing a telehealth screening protocol would provide families an opportunity to access highly trained clinicians and researchers with specialized expertise for initial screening before undertaking the cost and effort required to travel to a center. The first six months of funding will be used to develop, refine, and pilot test this parent-administered protocol in a sample of diverse infants 6-12 months (Aim 1). Feedback from parents and experts will inform final adaptations. The resulting protocol will subsequently be tested via telehealth in a pilot feasibility phase (Aim 2). 30 infants 6-12 months with early ASD symptoms and their caregivers will be recruited nationally, and will complete the telehealth screener quarterly for one year. We will examine the reliability of telehealth-derived measures of infant behavior across consecutive administrations, and compare these measures to existing parent-report measures to assess their validity. Acceptability to parents and feasibility of this telehealth approach to screening will also be evaluated. The overall goal of this project is to develop a protocol for systematically screening, assessing, and monitoring symptomatic infants from a distance. Doing so will increase families' access to specialized evaluations and decrease the significant waiting time between parents' first concerns and infants' first evaluation. It will also lay the groundwork for future efforts to conduct screening and intervention trials and will ultimately help to increase access to high-quality interventions and improve the developmental outcomes of many more underserved children with ASD.

项目概要 该提案的总体目标是开发一种用于筛查 6-12 岁婴儿的远程医疗程序 几个月大时出现早期自闭症谱系障碍 (ASD) 症状。虽然有些有希望 已确定该年龄段婴儿的生物标志物，但神经生物学方法尚未确定 广泛实施是可行的，特别是在农村和资源匮乏的服务系统中。 有早期担忧的家庭面临评估的漫长等待名单，并且经常必须旅行 远距离在具有适当专业知识的中心进行评估。远程医疗已被使用 作为增加获得跨多个学科服务的机会的一种具有成本效益的方法，以及 远程医疗治疗方法在 ASD 中得到了一些初步应用，但目前还没有 建立了远程健康筛查程序来筛查婴儿的 ASD。开发远程医疗 筛查方案将为家庭提供接触训练有素的临床医生和 具有专业知识的研究人员在承担成本和精力之前进行初步筛选 需要前往中心。前六个月的资金将用于开发、完善和 在 6-12 个月的不同婴儿样本中对这种父母管理的方案进行试点测试（目标 1）。 家长和专家的反馈将为最终的调整提供依据。由此产生的协议将 随后在试点可行性阶段通过远程医疗进行测试（目标 2）。 30 名 6-12 个月婴儿 具有早期 ASD 症状的患者及其护理人员将在全国范围内招募，并将完成 远程医疗筛查仪每季度一次，为期一年。我们将检查远程医疗衍生的可靠性 连续给药期间婴儿行为的测量，并比较这些测量 现有的家长报告措施来评估其有效性。家长的接受度和可行性 还将评估这种远程医疗筛查方法的效果。该项目的总体目标是 制定系统筛查、评估和监测症状的方案 远方的婴儿。这样做将增加家庭获得专门评估和 减少父母的首要关注点和婴儿的首要关注点之间的显着等待时间 评估。它还将为未来的筛查和干预工作奠定基础 试验，最终将有助于增加获得高质量干预措施的机会并改善 更多服务不足的自闭症谱系障碍儿童的发展成果。