Anxiety Outcomes in Cognitive-Behavioral Therapy vs. Light Therapy for Seasonal Affective Disorder

认知行为疗法与光照疗法治疗季节性情感障碍的焦虑结果

• 批准号: 10029783
• 负责人: KELLY J. ROHAN
• 金额: $ 1.65万
• 依托单位: UNIVERSITY OF VERMONT & ST AGRIC COLLEGE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2023-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10029783
• 关键词: Acute; Aftercare; American Psychiatric Association; Antidepressive Agents; Anxiety; Anxiety Disorders; Clinical; Clinical Trials; Cognitive Therapy; Conflict (Psychology); DSM-V; Diagnostic; Dimensions; Disease remission; Dropout; Equipment and supply inventories; Feeling suicidal; Impairment; Individual; Intake; Interview; Literature; Measures; Mental Depression; Modality; Outcome; Parents; Pathological anxiety; Patients; Pattern; Pharmaceutical Preparations; Pharmacology; Pharmacotherapy; Phototherapy; Prognostic Marker; Randomized Clinical Trials; Recurrence; Reporting; Research; Risk; Role; Seasonal Affective Disorder; Severities; Structure; Syndrome; Treatment outcome; Work; World Health Organization; anxiety symptoms; comorbid depression; comorbidity; comparative efficacy; depressed patient; disability; falls; follow-up; improved; individualized medicine; meetings; optimal treatments; patient response; precision medicine; profiles in patients; prognostic; single episode major depressive disorder; treatment effect; treatment response; trial comparing

Project Summary/Abstract Depression and anxiety are highly comorbid, and this comorbidity is a negative prognostic indicator of treatment outcomes with antidepressant medication. However, research conflicts on the effects of comorbid anxiety on outcomes with cognitive-behavioral therapy (CBT) for depression. The role of comorbid anxiety in treating a subtype of depression, winter seasonal affective disorder (SAD), has yet to be studied. The current project proposes to examine anxiety as both an outcome and a moderator of treatment outcomes in a parent trial comparing light therapy and CBT tailored to SAD (CBT-SAD). Aim 1 will examine anxiety as an outcome after acute treatment and at a follow-up one winter later. Aims 2 and 3 will examine baseline anxiety—both dimensional and syndromal anxiety, respectively—as a predictor of SAD treatment outcomes at post-treatment and at a follow-up one winter later. Anxiety disorders will be assessed using the Structured Clinical Interview for DSM-5 (SCID-5) at intake. Anxiety will be dimensionally assessed using the Beck Anxiety Inventory (BAI) at pre-, mid-, and post- treatment, as well as at the one winter follow-up.

项目摘要/摘要 抑郁和焦虑是高度并存的，这种并存是一种负面的预后。 抗抑郁药物治疗结果的指标。然而，研究在以下方面存在冲突 共病焦虑对认知行为疗法(CBT)疗效的影响 抑郁症。共病焦虑在治疗冬季季节性抑郁症亚型中的作用 情感障碍(SAD)，尚未被研究。目前的项目建议研究焦虑症 在比较LIGH的双亲试验中既是结果又是治疗结果的调节者 治疗和针对SAD量身定制的CBT(CBT-SAD)。目标1将检查焦虑作为一种结果 急性治疗，并在一年冬天后进行随访。目标2和目标3将检查基线 焦虑--分别是维度焦虑和综合症焦虑--作为SAD的预测因子 治疗后和一个冬季后的随访中的治疗结果。焦虑症会 在入院时使用DSM-5(SCID-5)结构化临床访谈进行评估。焦虑会 在治疗前、治疗中和治疗后使用贝克焦虑量表(BAI)进行维度评估 治疗，以及在一个冬季的随访。