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Anxiety Outcomes in Cognitive-Behavioral Therapy vs. Light Therapy for Seasonal Affective Disorder

认知行为疗法与光照疗法治疗季节性情感障碍的焦虑结果

基本信息

批准号：
10029783
负责人：
KELLY J. ROHAN
金额：
$ 1.65万
依托单位：
UNIVERSITY OF VERMONT & ST AGRIC COLLEGE
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-05-01 至 2023-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10029783
关键词：
Acute Aftercare American Psychiatric Association Antidepressive Agents Anxiety Anxiety Disorders Clinical Clinical Trials Cognitive Therapy Conflict (Psychology)DSM-V Diagnostic Dimensions Disease remission Dropout Equipment and supply inventories Feeling suicidal Impairment Individual Intake Interview Literature Measures Mental Depression Modality Outcome Parents Pathological anxiety Patients Pattern Pharmaceutical Preparations Pharmacology Pharmacotherapy Phototherapy Prognostic Marker Randomized Clinical Trials Recurrence Reporting Research Risk Role Seasonal Affective Disorder Severities Structure Syndrome Treatment outcome Work World Health Organization anxiety symptoms comorbid depression comorbidity comparative efficacy depressed patient disability falls follow-up improved individualized medicine meetings optimal treatments patient response precision medicine profiles in patients prognostic single episode major depressive disorder treatment effect treatment response trial comparing

项目摘要

Project Summary/Abstract Depression and anxiety are highly comorbid, and this comorbidity is a negative prognostic indicator of treatment outcomes with antidepressant medication. However, research conflicts on the effects of comorbid anxiety on outcomes with cognitive-behavioral therapy (CBT) for depression. The role of comorbid anxiety in treating a subtype of depression, winter seasonal affective disorder (SAD), has yet to be studied. The current project proposes to examine anxiety as both an outcome and a moderator of treatment outcomes in a parent trial comparing light therapy and CBT tailored to SAD (CBT-SAD). Aim 1 will examine anxiety as an outcome after acute treatment and at a follow-up one winter later. Aims 2 and 3 will examine baseline anxiety—both dimensional and syndromal anxiety, respectively—as a predictor of SAD treatment outcomes at post-treatment and at a follow-up one winter later. Anxiety disorders will be assessed using the Structured Clinical Interview for DSM-5 (SCID-5) at intake. Anxiety will be dimensionally assessed using the Beck Anxiety Inventory (BAI) at pre-, mid-, and post- treatment, as well as at the one winter follow-up.

项目总结/摘要抑郁和焦虑是高度共病的，这种共病是一种消极的预后抗抑郁药物治疗结果的指标。然而，研究冲突共病焦虑对认知行为治疗（CBT）结果的影响，萧条共病焦虑在治疗冬季抑郁症亚型中的作用情感障碍（SAD）尚未研究。目前的项目建议检查焦虑作为治疗结果的结果和调节剂，针对SAD的CBT治疗（CBT SAD）。目标1将检查焦虑作为一个结果后，急性治疗和一个冬天后的随访。目标2和3将审查基线焦虑-维度焦虑和综合征焦虑-作为SAD的预测因子治疗后和一个冬天后随访时的治疗结果。焦虑症会在入院时使用DSM-5（SCID-5）的结构化临床访谈进行评估。焦虑会在治疗前、治疗中和治疗后使用贝克焦虑量表（BAI）进行维度评估治疗，以及在一个冬季随访。