Targeting Surgeons' Decision Making for Lip Revision Surgery

针对外科医生唇部修复手术的决策

• 批准号: 10037998
• 负责人: CARROLL ANN TROTMAN
• 金额: $ 7.66万
• 依托单位: TUFTS UNIVERSITY BOSTON
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-03 至 2021-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10037998
• 关键词: Affect; Bilateral; Birth; Caring; Child; Cleft Lip; Cleft lip with or without cleft palate; Clinical; Decision Making; Evaluation; Face; Goals; Grant; Image; Intervention; Interview; Lip structure; Measures; National Institute of Dental and Craniofacial Research; Operative Surgical Procedures; Patients; Phase; Principal Investigator; Process; Protocols documentation; Randomized Clinical Trials; Research; Schedule; Site; Surgeon; System; United States; Visual Aid; cleft lip and palate; cohort; design; disability; experience; novel; orofacial cleft; prospective; repaired; surgery outcome; treatment planning

Principal Investigator: Carroll Ann Trotman, BDS, MA, MS NIDCR Protocol Number: 15-069-E/ NIDCR Grant Number: U01 DE024503 Targeting Surgeons’ Decision-Making for Cleft Lip Surgery PROTOCOL SUMMARY This study includes: (1) A group of surgeon-raters who will review images and quantitative information of patients with Cleft Lip and Palate (CL/P); and (2) Two prospective groups/cohorts of patients with cleft lip/palate (CL/P) – one cohort recommended to have secondary lip revision surgery and another slated to have primary lip repair surgery. The study will assign surgeon-raters to evaluate patients who are scheduled to be treated at another participating study site. Each surgeon-rater will be assigned to hypothetically assess several patients from both cohorts for surgery. Surgeon-raters will use a novel pre-surgical planning system for this evaluation – the Systematic Assessment for Facial Surgery (SAFS) Intervention. Subsequent to each SAFS, surgeon-raters will participate in an In-depth interview (IDI), designed to illuminate the surgeon-raters’ decision making process. This study will determine how the SAFS Intervention affects surgeons’ decision-making and treatment plans for surgery. Objectives: The Primary objectives of this study are: • To qualitatively assess how surgeon-raters integrate the SAFS’s objective measures and visual aids with the SAFS’s systematic subjective assessment in the decision-making process for the clinical surgical procedures of lip revision. • To qualitatively assess how surgeon-raters integrate the SAFS’s objective measures and visual aids with the SAFS’s systematic subjective assessment in the decision-making process for the clinical surgical procedures of primary lip repair. The secondary objectives of this study are: • To quantitatively assess the extent to which the SAFS changes surgeon-raters’ problem list and treatment planning goals for lip revision. • To quantitatively assess the extent to which the SAFS changes surgeon-raters’ problem list and treatment planning goals for primary lip repair. • To quantitatively assess the extent to which the SAFS changes surgeon-raters’ problem list and treatment planning goals for lip revision as a function of surgical expertise.

首席研究员：卡罗尔·安·特罗特曼（Carroll Ann Trotman），马萨诸塞州，马萨诸塞州，MS NIDCR协议编号：15-069-E/ NIDCR赠款号：U01 DE024503 针对外科医生的唇裂手术决策 协议摘要 这项研究包括：（1）一组将审查图像和定量信息的外科医生。 唇裂和pa裂的患者（Cl/p）； （2）患者的两个前瞻性组/同类 唇唇/pa/p（cl/p） - 一个同类建议进行次级唇部修订手术，另一种是 计划进行初级唇部修复手术。 该研究将分配外科医生，以评估计划在另一个人进行治疗的患者 参与研究地点。每个外科医生将被分配以假设评估几名患者 来自两个同龄人的手术。外科医生会议将使用新颖的手术前计划系统 评估 - 面部手术（SAFS）干预的系统评估。每个SAFS之后， 外科医生会议将参加深入的访谈（IDI），旨在阐明外科医生的访谈 决策过程。这项研究将确定SAFS干预如何影响外科医生 手术的决策和治疗计划。目标： 这项研究的主要目标是： •定性地评估外科医生如何整合SAFS的客观测量和视觉辅助工具 随着SAFS在临床决策过程中的系统评估 唇部修订的手术程序。 •定性地评估外科医生如何整合SAFS的客观测量和视觉辅助工具 随着SAFS在临床决策过程中的系统评估 原发性唇部修复的手术程序。 这项研究的次要目标是： •定量评估SAFS更改外科医生的问题清单的程度和 唇部修订的治疗计划目标。 •定量评估SAFS更改外科医生的问题清单的程度和 初级嘴唇修复的治疗计划目标。 •定量评估SAFS更改外科医生的问题清单的程度和 唇部修订的治疗计划目标是手术专业知识的函数。

项目成果

Specialized Pro-Resolving Mediators Reduce Scarring After Cleft Lip Repair.

• DOI: 10.3389/fimmu.2022.871200
• 发表时间: 2022
• 期刊: Frontiers in immunology
• 影响因子: 7.3

6-Shogaol promotes bone resorption and accelerates orthodontic tooth movement through the JNK-NFATc1 signaling axis.

• DOI: 10.1007/s00774-021-01245-y
• 发表时间: 2021-11
• 期刊: Journal of bone and mineral metabolism
• 影响因子: 3.3
• 作者: Zhu X;Yuan H;Ningjuan O;Trotman CA;Van Dyke TE;Chen JJ;Shen G
• 通讯作者: Shen G

Quantifying Soft Tissue Shape and Symmetry: Patients with Cleft Lip/Palate and Facial Paralysis.

量化软组织形状和对称性：唇/腭裂和面瘫患者。

• DOI: 10.1097/gox.0000000000001715
• 发表时间: 2018
• 期刊: Plastic and reconstructive surgery. Global open
• 作者: Trotman,CarrollAnn;Faraway,Julian;Hadlock,Tessa;Banks,Caroline;Jowett,Nathan;Regan,Daniel
• 通讯作者: Regan,Daniel