Targeting Surgeons' Decision Making for Lip Revision Surgery

针对外科医生唇部修复手术的决策

• 批准号: 10037998
• 负责人: CARROLL ANN TROTMAN
• 金额: $ 7.66万
• 依托单位: TUFTS UNIVERSITY BOSTON
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-03 至 2021-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10037998
• 关键词: Affect; Bilateral; Birth; Caring; Child; Cleft Lip; Cleft lip with or without cleft palate; Clinical; Decision Making; Evaluation; Face; Goals; Grant; Image; Intervention; Interview; Lip structure; Measures; National Institute of Dental and Craniofacial Research; Operative Surgical Procedures; Patients; Phase; Principal Investigator; Process; Protocols documentation; Randomized Clinical Trials; Research; Schedule; Site; Surgeon; System; United States; Visual Aid; cleft lip and palate; cohort; design; disability; experience; novel; orofacial cleft; prospective; repaired; surgery outcome; treatment planning

Principal Investigator: Carroll Ann Trotman, BDS, MA, MS NIDCR Protocol Number: 15-069-E/ NIDCR Grant Number: U01 DE024503 Targeting Surgeons’ Decision-Making for Cleft Lip Surgery PROTOCOL SUMMARY This study includes: (1) A group of surgeon-raters who will review images and quantitative information of patients with Cleft Lip and Palate (CL/P); and (2) Two prospective groups/cohorts of patients with cleft lip/palate (CL/P) – one cohort recommended to have secondary lip revision surgery and another slated to have primary lip repair surgery. The study will assign surgeon-raters to evaluate patients who are scheduled to be treated at another participating study site. Each surgeon-rater will be assigned to hypothetically assess several patients from both cohorts for surgery. Surgeon-raters will use a novel pre-surgical planning system for this evaluation – the Systematic Assessment for Facial Surgery (SAFS) Intervention. Subsequent to each SAFS, surgeon-raters will participate in an In-depth interview (IDI), designed to illuminate the surgeon-raters’ decision making process. This study will determine how the SAFS Intervention affects surgeons’ decision-making and treatment plans for surgery. Objectives: The Primary objectives of this study are: • To qualitatively assess how surgeon-raters integrate the SAFS’s objective measures and visual aids with the SAFS’s systematic subjective assessment in the decision-making process for the clinical surgical procedures of lip revision. • To qualitatively assess how surgeon-raters integrate the SAFS’s objective measures and visual aids with the SAFS’s systematic subjective assessment in the decision-making process for the clinical surgical procedures of primary lip repair. The secondary objectives of this study are: • To quantitatively assess the extent to which the SAFS changes surgeon-raters’ problem list and treatment planning goals for lip revision. • To quantitatively assess the extent to which the SAFS changes surgeon-raters’ problem list and treatment planning goals for primary lip repair. • To quantitatively assess the extent to which the SAFS changes surgeon-raters’ problem list and treatment planning goals for lip revision as a function of surgical expertise.

首席研究员：Carroll Ann Trotman，BDS、MA、MS NIDCR 方案编号：15-069-E/ NIDCR 授权编号：U01 DE024503 针对唇裂手术外科医生的决策 协议摘要 这项研究包括：(1) 一组外科医生评估者，他们将审查图像和定量信息 唇裂和腭裂 (CL/P) 患者的比例； (2) 两个前瞻性患者组/队列 唇裂/腭裂 (CL/P) – 一组建议进行二次唇部修复手术，另一组建议进行二次唇部修复手术 计划进行初次唇部修复手术。 该研究将指派外科医生评估员对计划在另一家医院接受治疗的患者进行评估 参与研究地点。每个外科医生评估员将被分配假设评估几名患者 来自两个队列进行手术。外科医生评估者将为此使用一种新颖的术前计划系统 评估——面部手术干预系统评估（SAFS）。每次 SAFS 之后， 外科医生评估者将参加深度访谈 (IDI)，旨在阐明外科医生评估者的观点 决策过程。这项研究将确定 SAFS 干预如何影响外科医生的 手术决策和治疗计划。目标： 本研究的主要目标是： • 定性评估外科医生评估者如何整合 SAFS 的客观测量和视觉辅助工具 SAFS 在临床决策过程中进行系统的主观评估 唇部修复手术。 • 定性评估外科医生评估者如何整合 SAFS 的客观测量和视觉辅助工具 SAFS 在临床决策过程中进行系统的主观评估 初次唇部修复的外科手术。 本研究的次要目标是： • 定量评估 SAFS 改变外科医生评估者问题清单的程度， 唇部修复的治疗计划目标。 • 定量评估 SAFS 改变外科医生评估者问题清单的程度， 初次唇部修复的治疗计划目标。 • 定量评估 SAFS 改变外科医生评估者问题清单的程度， 唇部修复的治疗计划目标作为手术专业知识的函数。

项目成果

Specialized Pro-Resolving Mediators Reduce Scarring After Cleft Lip Repair.

• DOI: 10.3389/fimmu.2022.871200
• 发表时间: 2022
• 期刊: Frontiers in immunology
• 影响因子: 7.3

6-Shogaol promotes bone resorption and accelerates orthodontic tooth movement through the JNK-NFATc1 signaling axis.

• DOI: 10.1007/s00774-021-01245-y
• 发表时间: 2021-11
• 期刊: Journal of bone and mineral metabolism
• 影响因子: 3.3
• 作者: Zhu X;Yuan H;Ningjuan O;Trotman CA;Van Dyke TE;Chen JJ;Shen G
• 通讯作者: Shen G

Quantifying Soft Tissue Shape and Symmetry: Patients with Cleft Lip/Palate and Facial Paralysis.

量化软组织形状和对称性：唇/腭裂和面瘫患者。

• DOI: 10.1097/gox.0000000000001715
• 发表时间: 2018
• 期刊: Plastic and reconstructive surgery. Global open
• 作者: Trotman,CarrollAnn;Faraway,Julian;Hadlock,Tessa;Banks,Caroline;Jowett,Nathan;Regan,Daniel
• 通讯作者: Regan,Daniel