A High Power, Broadband 395 GHz Gyrotron Amplifier for DNP-NMR and EPR Spectroscopy
A High Power, Broadband 395 GHz Gyrotron Amplifier for DNP-NMR and EPR Spectroscopy
批准号:
10010144
负责人:
Thorsten Maly
金额:
$36.59万
依托单位国家:
美国
项目类别:
财政年份:
2020
资助国家:
美国
项目状态:
已结题
起止时间:
2020-06-10 至 2021-05-31
关键词:
AcademiaAmplifiersAnalytical ChemistryAreaBenchmarkingBiologicalCell NucleusCodeCommunitiesComplexCrystallizationDevelopmentDevicesDimensionsElectron Spin Resonance SpectroscopyElectronsElementsFoundationsFrequenciesFundingGenerationsGunsHourIndustryLaboratoriesMagicMagnetismMeasurementMechanicsMembraneMethodsNMR SpectroscopyNoiseNuclearNuclear Magnetic ResonanceOutputPerformancePharmaceutical ChemistryPhasePhysicsPhysiologic pulseProductionPropertyProteinsResearchResearch PersonnelResolutionRunningSalesSamplingSignal TransductionSourceStructural ModelsStructureSystemTechnologyTestingTimeTravelTubeUnited States National Institutes of HealthVacuumX-Ray Crystallographydata acquisitiondesignelectrical propertyenhancing factorexperimental studyinstrumentationinterestirradiationmicrowave electromagnetic radiationmodels and simulationnext generationnoveloperationprogramsprotein structureprototypesimulationsoftware developmentsoftware systemssolid statesolid state nuclear magnetic resonancetransmission processvector
中文摘要
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英文摘要
Project Summary / Abstract
We propose to develop a novel gyro traveling wave tube amplifier (gyro-TWT) at 395 GHz with an output
power of 500 W and an operating bandwidth exceeding 3 GHz and a small signal gain > 45 dB. The amplifier
will be used in Dynamic Nuclear Polarization (DNP) enhanced Nuclear Magnetic Resonance (DNP-NMR)
experiments and Electron Paramagnetic Resonance (EPR) experiments. The output power of the proposed
amplifier is three orders greater than those available from solid-state sources at similar frequencies and the
operating bandwidth combined with the ability to coherently amplify complex input signals for use in DNP-NMR
and EPR will enable new generation of pulsed DNP-NMR and EPR experiments that are currently impossible
to perform with free running fixed frequency oscillators. This amplifier can upgrade the currently deployed
dozens of gyrotron oscillators for use in DNP-NMR and provide researchers with the ability of conducting
experiments with a broad range of polarizing agents without the need for a superconducting sweep coils in the
NMR magnet. Also, the amplifier will enable researchers to explore the promise of pulsed DNP-NMR
experiments. The proposed amplifier can be operated with a peak power 500 W with a duty factor of 10 % or in
continuous wave mode with an output power of 50 W.
In Phase I, we will design the amplifier system and perform detailed modeling and simulation of its
performance using benchmarked state-of-the-art design codes used in microwave tube research. We will
present a complete mechanical design of the system and verify the thermal and electrical properties using
commercial finite element codes. We will also build and test the cold performance of the most important
element of the system, namely, the interaction circuit and demonstrate its suitability for integration with the
tube. These tests will be performed on a Vector Network Analyzer to verify the microwave propagation
properties of the device. In Phase II, we will fabricate the electron gun, the internal mode converter and other
auxiliary components such as microwave windows etc. The entire system will be integrated and tested in our
laboratory to demonstrate the proposed output power and bandwidth.
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A High Power, Broadband 395 GHz Gyrotron Amplifier for DNP-NMR and EPR Spectroscopy
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批准号:10442892
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依托单位:
Compact Pulse Slicer for High-Power Submillimeter Waves
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批准号:10668508
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批准号:10010151
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资助金额:$22.73万
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财政年份:2020
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A Resonator for Pulsed ODNP Spectroscopy to Study Surface Hydration Dynamics
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批准号:10325293
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财政年份:2017
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负责人:Thorsten Maly
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依托单位:
An ODNP Probe to Study Hydration Dynamics in Membrane Protein
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批准号:9265623
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项目类别:
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资助金额:$6.18万
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财政年份:2015
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依托单位:
An ODNP Probe to Study Hydration Dynamics in Membrane Protein
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批准号:9896838
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项目类别:
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资助金额:$54.79万
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财政年份:2015
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负责人:Thorsten Maly
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依托单位:
Compact, Integrated EPR Spectrometer for Dynamic Nuclear Polarization
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批准号:8781173
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项目类别:
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资助金额:$18.56万
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财政年份:2014
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负责人:Thorsten Maly
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依托单位:
DNP-enhanced Tissue HRMAS MRS - Towards Measurements of Single-Cell Metabolomics
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批准号:8714386
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项目类别:
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资助金额:$20.55万
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财政年份:2014
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负责人:Thorsten Maly
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依托单位:
A Novel Ultra-Wideband Gyrotron for DNP-NMR Research
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资助金额:$23.84万
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依托单位:
An Integrated THz System for DNP-enhanced NMR Spectroscopy
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批准号:8591849
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项目类别:
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资助金额:$19.89万
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财政年份:2013
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负责人:Thorsten Maly
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依托单位:
A THz Resonator for Solid-State DNP-NMR Spectroscopy
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批准号:8454158
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项目类别:
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资助金额:$22.48万
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财政年份:2013
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负责人:Thorsten Maly
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依托单位:
An Integrated THz System for DNP-enhanced NMR Spectroscopy
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批准号:8921222
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项目类别:
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资助金额:$45.12万
-
财政年份:2013
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依托单位:
An Integrated THz System for DNP-enhanced NMR Spectroscopy
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批准号:8849046
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项目类别:
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资助金额:$51.5万
-
财政年份:2013
-
负责人:Thorsten Maly
-
依托单位:
High Sensitivity Solution DNP-NMR Probe with a Photonic Band Gap Resonator
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批准号:8313823
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项目类别:
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资助金额:$19.77万
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财政年份:2012
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负责人:Thorsten Maly
-
依托单位:
Compact System for Dynamic Nuclear Polarization Enhanced 600 MHz Solid-State NMR
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批准号:8000498
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项目类别:
-
资助金额:$18.51万
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财政年份:2010
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负责人:Thorsten Maly
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依托单位:
Compact System for Dynamic Nuclear Polarization Enhanced 600 MHz Solid-State NMR
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批准号:8146209
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项目类别:
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-
财政年份:2010
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负责人:Thorsten Maly
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依托单位:
海外基金