Laboratory Bench-Top EXAFS with STJ Spectrometer

配备 STJ 光谱仪的实验室台式 EXAFS

• 批准号: 10018070
• 负责人: Robin Cantor
• 金额: $ 64.4万
• 依托单位: STAR CRYOELECTRONICS, LLC
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-02-01 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10018070
• 关键词: Aluminum; Beryllium; Biochemistry; Biological; Chemical Engineering; Chemicals; Computer software; Crystallization; Custom; Data; Development; Devices; Electronics; Elements; Generations; Industrialization; Laboratories; Light; Measurement; Measures; Medical; Metals; Morphologic artifacts; NMR Spectroscopy; Noise; Output; Pharmacologic Substance; Polymers; Powder dose form; Price; Research Priority; Resolution; Roentgen Rays; Safety; Sampling; Science; Shapes; Signal Transduction; Site; Software Framework; Source; Spectrum Analysis; Spottings; Structure; Synchrotrons; System; Tantalum; Techniques; Testing; Thinness; Time; Universities; Vacuum; Work; absorption; animal tissue; base; cryostat; curve fitting; data acquisition; design; design and construction; detector; experimental study; improved; instrument; metal oxide; next generation; novel; operation; prototype; response; scale up; software development; structured data; success; synchrotron radiation; transmission process; user-friendly

PROJECT SUMMARY Extended X-ray absorption fine structure (EXAFS) spectroscopy is a technique that gives element-specific structural and chemical information about molecules. An enormous advantage of EXAFS spectroscopy is that it is readily applied to many different kinds of sample, including, solutions, powders, slurries, and animal tissues. Current EXAFS instruments require bright X-ray beams from specialized synchrotron lightsources for most samples, meaning that access is limited to priority research and the science that can be done is restricted by the need to work at remote sites as well as the often months-long wait for access. STAR Cryoelectronics intends to build a laboratory instrument to measure transmission EXAFS spectra to the same precision typically measured at synchrotron radiation sources and with comparable signal-to-noise. This project will involve improved energy-resolving X-ray detectors based on superconducting tunnel junctions (STJs) to achieve the energy resolution and efficiency needed to make EXAFS measurements feasible in a regular laboratory setting. The first aim is a plan to design and fabricate novel STJ detector chips for these next-generation X-ray detectors. STAR Cryoelectronics will build on previous success with tantalum-based STJs to produce novel aluminum junctions with tantalum absorbers capable of functioning to energies up to at least 11,000 eV. This part of the project will involve extensive testing as we refine the design and fabrication parameters. A second aim is to couple this new STJ detector with a sample chamber and broadband X-ray source to a complete, user-friendly EXAFS instrument. Associated with second aim is a significant software development project, intended to provide the end user an easy-to-use instrument. This will include instrument control, processing of EXAFS data in real-time during data acquisition, and the ability to analyze data during data acquisition. This latter ability should not only provide preliminary results, but allow assessment of data and sample quality, thereby optimizing instrument time. This project’s ultimate aim is to make EXAFS a routine laboratory technique, alongside more well-known spectroscopies such as UV-visible spectroscopy, IR spectroscopy, and NMR spectroscopy. While the proposed laboratory transmission EXAFS instrument should be complementary to synchrotron lightsource based EXAFS, it should nonetheless reduce the need to apply for access to synchrotrons for EXAFS, open up the technique for more general and routine chemical and biological applications, and enable new scientific opportunities and novel spectroscopic applications. 1

项目摘要 扩展X射线吸收精细结构（EXAFS）光谱是一种给出元素特异性的技术。 分子的结构和化学信息。EXAFS光谱的一个巨大优势是 它易于应用于许多不同种类的样品，包括溶液、粉末、浆液和动物样品。 组织中目前的EXAFS仪器需要来自专门的同步加速器光源的明亮X射线束 对于大多数样本，这意味着访问仅限于优先研究，可以完成的科学是 由于需要在偏远地点工作以及通常长达数月的访问等待， 星星低温电子公司打算建立一个实验室仪器来测量透射EXAFS光谱， 通常在同步辐射源处测量相同的精度，并且具有可比的信噪比。这 一个项目将涉及基于超导隧道结的改进的能量分辨X射线探测器 （STJ）以实现EXAFS测量可行所需的能量分辨率和效率， 常规实验室设置。第一个目标是设计和制造新型STJ探测器芯片， 下一代X射线探测器星星Cryoelectronics公司将建立在以前的成功与钽基 STJ将生产具有钽吸收体的新型铝结，其能量可高达 至少11,000 eV。该项目的这一部分将涉及广泛的测试，因为我们完善的设计和制造 参数第二个目标是将这种新的STJ探测器与样品室和宽带X射线 源到一个完整的，用户友好的EXAFS仪器。与第二个目标相关的是一个重要的软件 开发项目，旨在为最终用户提供一个易于使用的仪器。这将包括仪器 控制，在数据采集过程中实时处理EXAFS数据，以及在数据采集过程中分析数据的能力。 数据采集后一种能力不仅应提供初步结果，还应允许对数据进行评估 和样品质量，从而优化仪器时间。 该项目的最终目标是使EXAFS成为常规的实验室技术， 光谱学如UV-可见光谱学、IR光谱学和NMR光谱学。而 建议实验室传输EXAFS仪器应补充同步光源 尽管如此，它应该减少申请EXAFS同步加速器的需要， 该技术用于更一般和常规的化学和生物应用，并使新的科学 机会和新的光谱应用。 1

项目成果

Feasibility of Laboratory-Based EXAFS Spectroscopy with Cryogenic Detectors.

• DOI: 10.1007/s10909-020-02474-7
• 发表时间: 2020-09
• 期刊: Journal of low temperature physics
• 影响因子: 2
• 作者: George SJ;Carpenter MH;Friedrich S;Cantor R
• 通讯作者: Cantor R