San Francisco Bay Clinical Trials Unit (CTU)

项目总结 旧金山湾区经历了特别严重的艾滋病毒流行，男性 与受影响最大的男性(MSM)、黑人和拉丁裔人群发生性关系 区域；以及移民者和注射吸毒者是重要的接触人群。 苏珊·布赫宾德博士和黛安·哈夫利尔博士是艾滋病毒预防和治疗的科学领导者， 分别进行了分析。他们将共同领导旧金山湾区临床试验部门(SFBay CTU)，隶属于ACTG、HPTN和HVTN。这个综合研究机构将 通过这些网络实现三个具体目标：1)推进预防和治疗 临床试验网络中的科学及其交叉；2)实施临床试验 高效并出色地遵守协议，同时让不同的社区参与；以及3) 培养新一代艾滋病毒预防和治疗科学领域的多元化领导者。戴维斯博士。 布赫宾德和哈夫利尔加入了一批才华横溢的调查人员的行列，他们提供了 网络中的领导力，在众多科学领导力委员会和 工作组，并主持一系列预防和治疗议定书。两个临床 研究网站，桥梁艾滋病毒CRS(隶属于HVTN和HPTN，由Hyman博士领导 Scott)和UCSF CRS(隶属于ACTG，由Annie Leutkmeyer博士领导)已经 在注册、保留和遵守协议要求方面的卓越记录，以及 积极参与整个旧金山湾区的当地社区。此应用程序 代表SFBay CTU的更新，有几个改进，包括新的领导层 由一群有经验的、多样化的调查人员；将社区项目整合到 单一、地位中立的团队；扩大社区参与和向东部招募 和旧金山南湾；以及全面整合各方面的早期调查人员 SFBay CTU的科学研究。通过平稳运行的研究基础设施， 科学、运营和社区参与指导委员会，SFBay CTU 致力于继续在ACTG、HPTN和HVTN中发挥领导作用，并为 艾滋病毒预防、治疗和治疗科学取得突破。

Project summary The San Francisco Bay Area has experienced a particularly intense HIV epidemic, with men who have sex with men (MSM), Black, and Latinx populations most heavily impacted in the region; and transpeople and people who inject drugs important populations for engagement. Drs. Susan Buchbinder and Diane Havlir are scientific leaders in HIV prevention and treatment, respectively. Together they will lead the San Francisco Bay Area Clinical Trials Unit (SFBay CTU), affiliated with the ACTG, HPTN, and HVTN. This integrated research organization will accomplish 3 specific aims through these Networks: 1) advance prevention and treatment science and their intersection within the Clinical Trials Networks; 2) implement clinical trials efficiently and with excellent adherence to protocol while engaging diverse communities; and 3) develop a new generation of diverse leaders in HIV prevention and treatment science. Drs. Buchbinder and Havlir are joined by a diverse pool of talented investigators who have provided leadership across the Networks, serving on numerous scientific leadership committees and working groups and chairing a range of prevention and treatment protocols. The two Clinical Research Sites, the Bridge HIV CRS (affiliated with HVTN and HPTN and led by Dr. Hyman Scott) and the UCSF CRS (affiliated with ACTG and led by Dr. Annie Leutkemeyer) have records of excellence in enrollment, retention, and adherence to protocol requirements, and actively engage local communities throughout the San Francisco Bay Area. This application represents a renewal of the SFBay CTU, with several improvements, including new leadership by an accomplished, diverse group of investigators; integration of community programs into a single, status-neutral team; expansion of community engagement and recruitment into the East and South Bays of San Francisco; and full integration of early stage investigators in all aspects of the science of the SFBay CTU. Through a smoothly running research infrastructure, divided into Scientific, Operational, and Community Engagement Steering Committees, the SFBay CTU is committed to continued leadership in the ACTG, HPTN, and HVTN, and contributing to breakthroughs in the science of HIV prevention, treatment, and cure.