Optimizing Inclusion of Blacks Within a Dietary Change Intervention to Reduce Hypertension

优化将黑人纳入饮食改变干预措施以减少高血压

• 批准号: 10075657
• 负责人: Dori Marie Steinberg
• 金额: $ 4.47万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-04-10 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10075657
• 关键词: Adherence; Adult; Affect; African American; American; Award; Cardiovascular Diseases; Cause of Death; Cellular Phone; Cholesterol; Clinical Research; Clinical Trials; Complement; Consumption; DASH diet; Data; Diet; Dietary Practices; Disease; Educational Background; Effectiveness; Ensure; Ethnic group; Fatty acid glycerol esters; Fiber; Focus Groups; Food; Gender; Goals; Government; Health; High Prevalence; Hypertension; Institution; Intervention; Intervention Studies; Intervention Trial; Interview; Linguistics; Medical Research; Methods; Motivation; National Health and Nutrition Examination Survey; Outcomes Research; Ownership; Parents; Participant; Patient Recruitments; Pilot Projects; Population; Population Heterogeneity; Prevalence; Proteins; Race; Research; Research Personnel; Sampling; Sampling Studies; Structure; Surveys; Testing; Time; Translating; Treatment Efficacy; United States; Woman; blood pressure reduction; clinical application; clinically relevant; design; dietary adherence; dietary guidelines; digital; effective therapy; ethnic minority population; evidence base; experience; fruits and vegetables; gender difference; heart disease risk; higher education; improved; men; public health relevance; racial and ethnic; recruit; saturated fat; success; therapy development; tool

ABSTRACT Nearly 50% of adults in the United States have high blood pressure, a leading contributor to cardiovascular disease. The prevalence of high blood pressure is even greater among black adults (55%), more than other racial and ethnic groups. The DASH (Dietary Approaches to Stop Hypertension) dietary pattern is an evidence- based strategy to treat high blood pressure that has become part of the Dietary Guidelines for Americans. DASH promotes a diet rich in fruits and vegetables, low-fat dairy, high fiber and protein, and controlled amounts of total fat, cholesterol and saturated fat. This dietary pattern leads to a significantly greater reduction in blood pressure among blacks compared to whites. Though DASH effects are promising for blacks, adherence has been limited in this group as evidenced by national survey and clinical trial data. To understand how DASH adherence can be improved among blacks, sufficient representation in clinical trials is necessary. More inclusive and representative recruitment is a critical starting point to producing broadly- relevant clinical trial results. The overarching aim of DASH Cloud, the parent study, connected to this supplement is to improve the efficacy of the intervention on diet quality. The parent study aims to recruit at least 40% racial/ethnic minorities. This supplemental proposal will complement the parent trial aims by examining factors that may influence black subjects’ participation and success in improving DASH dietary quality. We aim to 1) determine the barriers and facilitators of dietary quality in black adults, and 2) determine the effectiveness of DASH Cloud intervention recruitment methods.

摘要 在美国，近50%的成年人患有高血压，这是心血管疾病的主要原因。 疾病高血压的患病率在黑人成年人中甚至更高（55%），比其他人更高。 种族和民族群体。DASH（Dietary Approaches to Stop Hypertension，停止高血压的饮食方法）饮食模式是一个证据- 治疗高血压的基本策略已经成为美国人饮食指南的一部分。 DASH提倡富含水果和蔬菜、低脂乳制品、高纤维和蛋白质的饮食， 总脂肪、胆固醇和饱和脂肪的量。这种饮食模式导致了显著更大的减少 与白人相比，黑人的血压。尽管DASH效应对黑人来说很有希望， 如全国调查和临床试验数据所证明的，这一群体的依从性有限。 为了了解如何在黑人中改善DASH依从性，临床试验中有足够的代表性 是必要的.更具包容性和代表性的招聘是广泛生产的关键起点- 相关临床试验结果。母研究DASH Cloud的首要目标与此相关 补充是为了提高对饮食质量的干预效果。家长研究旨在招募 至少40%的种族/少数民族。本补充提案将通过以下方式补充母试验目标： 检查可能影响黑人受试者参与和成功改善DASH饮食的因素 质量.我们的目标是1）确定黑人成年人饮食质量的障碍和促进因素，2）确定 DASH云干预招募方法的有效性。