Reading and eye-hand coordination in amblyopic children

弱视儿童的阅读和眼手协调能力

• 批准号: 10078433
• 负责人: Krista Rose Kelly
• 金额: $ 7.14万
• 依托单位: RETINA FOUNDATION OF THE SOUTHWEST
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10078433
• 关键词: Adult; Affect; Age; Amblyopia; Anisometropia; Child; Cities; Code; Country; County; Data; Development; Devices; Enrollment; Eye; Eye Movements; Foundations; Hand; Impairment; Instruction; Intervention; Literature; Location; Monocular Vision; Motion; Motor; Motor Skills; Movement; Names; Principal Investigator; Province; Reading; Retina; Saccades; Schools; Sensory; Strabismus; System; Texas; Visual; Visual Acuity; Visual impairment; design; experience; experimental study; eye hand coordination; gaze; grasp; kinematics; motor deficit; motor disorder; motor impairment; oculomotor; performance site; programs; skills; success; vision development; visual motor; visual tracking

Program Director/Principal Investigator (Last, First, Middle): Kelly, Krista, Rose PROJECT SUMMARY (See instructions): Amblyopia is the most common cause of monocular vision impairment among children, affecting 2 or 3 of every 100 children. Amblyopia commonly results when there is binocularly discordant input associated with strabismus or anisometropia during visual development. Sensory and ocular motor deficits are well-established in the amblyopia literature. The functional consequences of amblyopia on the developing visuocognitive and visuomotor systems are less known. Initial studies show slow reading and poor fine motor ability in amblyopic children and adults, even when they have one eye with normal visual acuity under binocular viewing conditions. Yet, causes of these impairments remain poorly understood. Strabismic and anisometropic children, with or without amblyopia, between the ages of 4-12 years will be enrolled and compared to a group of normal control children. Four projects will be conducted in these groups of children. Eye movements during reading will be evaluated using the EyeLink 1000 binocular eye tracking system, and temporal eye-hand coordination during visually-guided reach-to-point and during visually-guided precision grasp will be evaluated using the EyeLink 1000 and the LEAP Motion capture device. These studies will determine how sensory deficits (visual acuity, stereoacuity, suppression), ocular motor dysfunction (gaze instability, abnormal saccades), and deficits in visual planning and guidance of hand movements affect reading, reaching, and grasping in amblyopic children under binocular conditions. Data from the proposed experiments will determine the consequences of abnormal visual experience during development on the visuocognitive and visuomotor systems, provide information on sensory and motor integration during maturation, and aid in determining more effective amblyopia treatments and academic accommodations that allow amblyopic children to thrive. RELEVANCE (See instructions): Amblyopic children read slowly and have fine motor impairments. This project will evaluate factors associated with these deficits. These data will determine the effects of abnormal visual experience on developing visuocognitive and visuomotor systems, and will guide the design of school accommodations and interventions to promote academic success,and potentially open a new avenue for amblyopia treatment to surmount obstacles to proficient reading and adept visuomotor skills. PROJECT/PERFORMANCE SITE(S) (if additional space is needed, use Project/Performance Site Format Page) Project/Performance Site Primary Location Organizational Name: Retina Foundation of the Southwest DUNS: 127069466 Street 1: 9600 North Central Expressway Street 2: Suite #200 City: Dallas County: USA State: Texas Province: Country: Zip/Postal Code: 75206 Project/Performance Site Congressional Districts: TX-032 Additional Project/Performance Site Location Organizational Name: DUNS: Street 1: Street 2: City: County: State: Province: Country: Zip/Postal Code: Project/Performance Site Congressional Districts: PHS 398 (Rev. 01/18 Approved Through 03/31/2020) OMB No. 0925-0001 Page 2 Form Page 2

项目总监/主要研究者（最后一位，第一位，中间一位）：Kelly，Krista，Rose 项目总结（见说明）： 弱视是儿童单眼视力受损的最常见原因， 每100个孩子弱视通常是由于双眼不一致的输入， 在视觉发育过程中出现斜视或屈光参差。感觉和眼部运动缺陷是 在弱视文献中得到了很好的证实。弱视对发育中儿童的功能影响 视觉认知和视觉系统是不太为人所知的。最初的研究表明，缓慢的阅读和穷人罚款 弱视儿童和成人的运动能力，即使他们有一只眼睛视力正常 在双目观察条件下。然而，对这些缺陷的原因仍然知之甚少。 4-12岁的斜视和屈光参差儿童，无论是否患有弱视， 并与一组正常对照儿童进行比较。四个项目将在这些 一群一群的孩子将使用EyeLink 1000双目眼评价阅读期间的眼球运动 跟踪系统，以及在视觉引导到达点和 将使用EyeLink 1000和LEAP运动捕捉系统对视觉引导的精确抓取进行评估 设备.这些研究将确定感觉缺陷（视敏度、立体视敏度、抑制）、眼 运动功能障碍（凝视不稳定，异常扫视），以及视觉规划和引导的缺陷， 在双眼条件下，手的运动影响弱视儿童的阅读、伸手和抓握。 来自拟议实验的数据将确定异常视觉体验的后果 在视觉认知和视觉系统的发展过程中，提供有关感觉和 在成熟过程中的运动整合，并帮助确定更有效的弱视治疗， 让弱视儿童茁壮成长的学术设施。 相关性（参见说明）： 弱视儿童阅读速度慢，有细微的运动障碍。该项目将评估 与这些缺陷有关。这些数据将确定异常视觉体验对 开发视觉认知和视觉系统，并将指导学校住宿的设计 以及促进学业成功的干预措施，并可能为弱视开辟一条新的途径。 治疗，以克服障碍，熟练的阅读和熟练的视觉技能。 项目/履约现场（如果需要额外空间，请使用项目/履约现场格式页） 项目/绩效现场主要位置 西南视网膜基金会（Retina Foundation of the Southwest） 电话：127069466 街道1：9600 North Central Expressway街道2：Suite #200 城市：达拉斯县：美国州：德克萨斯州 邮编：75206 项目/表演场地国会区：TX-032 其他项目/绩效现场位置 组织名称： DUNS： 第一街：第二街： 城市：县：州： 邮政编码：邮政编码： 项目/绩效现场国会选区： PHS 398（修订版01/18批准至03/31/2020）OMB编号0925-0001 第2页：第2页