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中文摘要
翻译
膜作用肽 生物活性肽调节许多生理过程,在某些部位起内分泌或旁分泌作用 信号和其他神经递质或生长因子,对人类有重要和积极的影响, 健康,包括抗微生物、抗真菌、抗病毒和抗肿瘤活性。在这个项目中,我们将探索 一种新的膜作用肽的基本原理设计方法。我们将:1)设计和开发新的生物活性 基于膜上肽组装的肽; 2)研究肽在体外的生物学意义; 3) 评估有前景的肽对疾病细胞和共培养物的药学意义。
英文摘要
Membrane-Acting Peptides Bioactive peptides regulate many physiological processes, acting at some sites as endocrine or paracrine signals and at others as neurotransmitters or growth factors, have important and positive impacts on human health including antimicrobial, antifungal, antiviral, and antitumor activities. In this project, we will explore a new rationale design approach to membrane-acting peptides. We will: 1) design and develop new bioactive peptides based on on-membrane peptide assembly; 2) study the biological implications of peptides in vitro; 3) evaluate the pharmaceutical significance of promising peptides on disease cells and co-cultures.
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Engineered Intravascular Catheters for the Treatment of Bacteremia
  • 批准号:
    8676368
  • 项目类别:
  • 资助金额:
    $18.75万
  • 财政年份:
    2014
  • 负责人:
    JUN F LIANG
  • 依托单位:
Engineered Intravascular Catheters for the Treatment of Bacteremia
  • 批准号:
    8836488
  • 项目类别:
  • 资助金额:
    $22.5万
  • 财政年份:
    2014
  • 负责人:
    JUN F LIANG
  • 依托单位:
Biofilm Growth on Functionalized Surfaces
  • 批准号:
    7580106
  • 项目类别:
  • 资助金额:
    $23.16万
  • 财政年份:
    2009
  • 负责人:
    JUN F LIANG
  • 依托单位:
Biofilm Growth on Functionalized Surfaces
  • 批准号:
    7843515
  • 项目类别:
  • 资助金额:
    $19.21万
  • 财政年份:
    2009
  • 负责人:
    JUN F LIANG
  • 依托单位:
海外基金