Production Assistance for Cellular Therapies (PACT)- Cell Processing Facilities- Cell manufacturing and process development services for PCT0027-01: Clinical Production of Viral Specific T Cell Lines

细胞疗法生产协助 (PACT) - 细胞加工设施 - PCT0027-01 的细胞制造和工艺开发服务：病毒特异性 T 细胞系的临床生产

• 批准号: 10115178
• 负责人: CLIONA ROONEY
• 金额: $ 115.81万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-01-31 至 2021-01-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10115178
• 关键词: Adenoviruses; Antigens; BK Virus; Blood Banks; Cell Line; Cell Therapy; Cells; Clinical; Cytomegalovirus; Hematopoietic Stem Cell Transplantation; Human Herpesvirus 4; Immunoassay; In Vitro; Incidence; Investigational Drugs; Investigational New Drug Application; Patients; Peripheral Blood Mononuclear Cell; Prevention; Production; Services; Specificity; T-Lymphocyte; United States Food and Drug Administration; Viral; Viral Antigens; Virus; Virus Diseases; cell bank; design; effective therapy; experience; gene therapy; graft vs host disease; manufacturing process development

The overall objective is to manufacture and characterize a bank of T-cells specific for CMV, EBV, adenoviruses and BK virus (mVSTs).

总体目标是生产和表征CMV、EBV、腺病毒和BK病毒（mVST）特异性T细胞库。