A Follow-up Study for Causes of Cancer in Black Women
黑人女性癌症病因的后续研究
基本信息
- 批准号:10120183
- 负责人:
- 金额:$ 37.66万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2012
- 资助国家:美国
- 起止时间:2012-09-21 至 2022-08-31
- 项目状态:已结题
- 来源:
- 关键词:AffectAfrican AmericanAgeAgingAlgorithmsAlzheimer&aposs DiseaseAlzheimer&aposs disease related dementiaAlzheimer&aposs disease riskCancer EtiologyCellular PhoneCessation of lifeCognitionCohort StudiesDataEnrollmentFamily memberFollow-Up StudiesFutureGoalsHealthHealth behaviorIncidenceIndividualInternetLinkMalignant NeoplasmsManuscriptsMedicareMethodsNon-MalignantParticipantPatient Self-ReportPersonsPopulationPublishingQuestionnairesReportingRisk FactorsSocial Security NumberTestingTimeWomanWomen&aposs Healthcognitive functioncognitive testingcohortcostexperiencefollow-upindexingneoplasm registryprospectivepsychosocialracismsmartphone Applicationstressor
项目摘要
The Black Women's Health Study (BWHS) began in 1995 with the goal of studying risk factors for cancer
incidence and survival in African American (AA) women. 59,000 AA women ages 21-69 years (median age,
38) from 17 states across the U.S. enrolled by completing health questionnaires. Since then, data on health,
behaviors, and numerous other factors have been collected through biennial mailed and web questionnaires,
with follow-up successful for ~85% of potential person-years. Cancers are identified through self-report, cancer
registries, the National Death Index, and linkage with Medicare data. The study has published over 250
manuscripts to date on cancer and on nonmalignant illnesses as well. With the aging of the cohort (median age
now 63, range 45-93), it becomes important to study conditions, such as Alzheimer's Disease (AD) and related
dementias, that particularly affect aging populations and occur more commonly in AAs than white individuals.
We propose to study AD in the BWHS. We linked BWHS participants through their social security numbers to
Medicare data in 2013 and used an algorithm to identify AD cases. We identified 98 cases, of which only 12
had been self-reported or reported by family members for that year. We propose to identify AD cases in the
entire 10 years of Medicare data to which we have now linked BWHS participants (2007-2016), which should
yield ~800 cases. Psychosocial stressors have been linked to poorer cognition, and an important such stressor
that occurs commonly among AAs is experiences of perceived racism. We propose to prospectively assess
perceived experiences of everyday and institutional racism reported by BWHS participants on BWHS
questionnaires in relation to subsequent incident AD identified in the 10 years of Medicare data. We also
propose to test a potential method for tracking the cognitive function of large populations at reasonable cost.
We will do so through a smart phone app with cognitive tests that BWHS participants will install on their smart
phones. We propose to enroll 200 BWHS participants from across the U.S. who agree to install an app called
DANA on their smart phones and to complete the cognitive tests (20 minutes) immediately after installation and
6 months later. This study will provide informative data on whether older AA women are willing and able to be
tracked for cognition through an app. If this goal turns out to be feasible, it will then be possible in the future to
enroll a large number of BWHS participants for this purpose.
黑人妇女健康研究(BWHS)始于1995年,目的是研究癌症的危险因素
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Julie R Palmer其他文献
Planetary Health Diet Index in relation to mortality in a prospective cohort study of United States Black females
一项针对美国黑人女性的前瞻性队列研究:行星健康饮食指数与死亡率的关系
- DOI:
10.1016/j.ajcnut.2025.01.023 - 发表时间:
2025-03-01 - 期刊:
- 影响因子:6.900
- 作者:
Yifei Shan;Kimberly A Bertrand;Jessica L Petrick;Shanshan Sheehy;Julie R Palmer - 通讯作者:
Julie R Palmer
Hormone therapy use and young-onset breast cancer: a pooled analysis of prospective cohorts included in the Premenopausal Breast Cancer Collaborative Group
激素治疗的使用与早发性乳腺癌:绝经前乳腺癌协作组纳入的前瞻性队列的荟萃分析
- DOI:
10.1016/s1470-2045(25)00211-6 - 发表时间:
2025-07-01 - 期刊:
- 影响因子:35.900
- 作者:
Katie M O’Brien;Melissa G House;Mandy Goldberg;Michael E Jones;Clarice R Weinberg;Amy Berrington de Gonzalez;Kimberly A Bertrand;William J Blot;Jessica Clague DeHart;Fergus J Couch;Montserrat Garcia-Closas;Graham G Giles;Victoria A Kirsh;Cari M Kitahara;Woon-Puay Koh;Hannah Lui Park;Roger L Milne;Julie R Palmer;Alpa V Patel;Thomas E Rohan;Dale P Sandler - 通讯作者:
Dale P Sandler
Julie R Palmer的其他文献
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{{ truncateString('Julie R Palmer', 18)}}的其他基金
Evaluating the Feasibility of Lung Cancer Screening in High-Risk Black Women
评估高危黑人女性肺癌筛查的可行性
- 批准号:
10649976 - 财政年份:2023
- 资助金额:
$ 37.66万 - 项目类别:
Testing scalable communication modalities for returning breast cancer genetic research results to African American women
测试可扩展的通信方式,将乳腺癌基因研究结果返回给非裔美国女性
- 批准号:
10332737 - 财政年份:2020
- 资助金额:
$ 37.66万 - 项目类别:
Testing scalable communication modalities for returning breast cancer genetic research results to African American women
测试可扩展的通信方式,将乳腺癌基因研究结果返回给非裔美国女性
- 批准号:
10191042 - 财政年份:2020
- 资助金额:
$ 37.66万 - 项目类别:
Improving Breast Cancer Risk Prediction for African American Women: Consideration of Estrogen Receptor Subtype-Specific Risk Factors
改善非裔美国女性乳腺癌风险预测:考虑雌激素受体亚型特异性风险因素
- 批准号:
10322441 - 财政年份:2019
- 资助金额:
$ 37.66万 - 项目类别:
Improving Breast Cancer Risk Prediction for African American Women: Consideration of Estrogen Receptor Subtype-Specific Risk Factors
改善非裔美国女性乳腺癌风险预测:考虑雌激素受体亚型特异性风险因素
- 批准号:
10544725 - 财政年份:2019
- 资助金额:
$ 37.66万 - 项目类别:
A Prospective Investigation of the Oral Microbiome and Pancreatic Cancer
口腔微生物组与胰腺癌的前瞻性研究
- 批准号:
8964197 - 财政年份:2015
- 资助金额:
$ 37.66万 - 项目类别:
A Prospective Investigation of the Oral Microbiome and Pancreatic Cancer
口腔微生物组与胰腺癌的前瞻性研究
- 批准号:
9540692 - 财政年份:2015
- 资助金额:
$ 37.66万 - 项目类别:
A Prospective Investigation of the Oral Microbiome and Pancreatic Cancer
口腔微生物组与胰腺癌的前瞻性研究
- 批准号:
9326247 - 财政年份:2015
- 资助金额:
$ 37.66万 - 项目类别:
A Prospective Investigation of the Oral Microbiome and Pancreatic Cancer
口腔微生物组与胰腺癌的前瞻性研究
- 批准号:
9140058 - 财政年份:2015
- 资助金额:
$ 37.66万 - 项目类别:
A Follow-up Study for Causes of Cancer in Black Women
黑人女性癌症病因的后续研究
- 批准号:
10005917 - 财政年份:2012
- 资助金额:
$ 37.66万 - 项目类别:
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