Integrating a combination HIV prevention intervention into a widely-used geosocial app for Chinese MSM

将艾滋病毒预防综合干预措施纳入中国 MSM 广泛使用的地理社交应用程序中

• 批准号: 10079463
• 负责人: Aaron Julius Siegler
• 金额: $ 61.64万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-01-23 至 2023-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10079463
• 关键词: AIDS prevention; AIDS/HIV problem; Appointment; Behavioral; Biological Factors; Books; Canada; Caring; China; Chinese People; Cities; Clinic; Cross-Sectional Studies; Custom; Data; Data Collection; Detection; Development; Diagnosis; Diagnostic Reagent Kits; Epidemic; Event; Exercise; Exposure to; Focus Groups; HIV; HIV diagnosis; HIV/STD; Health; Hearing; Home; Home Care Services; Human immunodeficiency virus test; Incidence; India; Individual; Intervention; Intervention Studies; Lubricants; Mexico; Modeling; NIH Office of AIDS Research; Nongovernmental Organizations; Participant; Patients; Persons; Pilot Projects; Population; Prevention; Process; Public Health; Research; Research Priority; Resources; Review Literature; Risk; Schedule; Service delivery model; Services; Sexual Health; Strategic Planning; Structure; Surveys; System; Testing; Time; Treatment Efficacy; Trust; United States; Work; acceptability and feasibility; base; cognitive interview; cohort; condomless anal sex; condoms; design; efficacy study; experience; high risk; home based service; home test; interest; mathematical model; meetings; men who have sex with men; novel; pre-exposure prophylaxis; prevention service; preventive intervention; programs; public health intervention; recruit; satisfaction; scale up; self testing; service delivery; service intervention; service uptake; smartphone Application; successful intervention; tool; transmission process

PROJECT SUMMARY/ABSTRACT A number of HIV prevention interventions are known to be effective: HIV testing and linkage to care as appropriate, condom use, and HIV pre-exposure prophylaxis (PrEP). Unfortunately, achieving sufficient use of these prevention services has been challenging. In China, men who have sex with men (MSM) are the only risk group with increasing HIV case detection, representing 26% of new cases diagnosed in 2014. One way to obtain increased prevention intervention use would be to help individuals understand when they should be using certain prevention services, and to make accessing services less burdensome. The proposed research will involve conducting a literature review and developing mathematical models to explore different scenarios of providing a combination HIV prevention service intervention for MSM in China. Using information from this exercise, we will develop and pilot test a combination HIV intervention built into a smartphone app. The intervention will include home care services such as home HIV self-testing and home ordering of prevention products such as condoms. If the intervention proves to be feasible and acceptable, the pilot test will facilitate design of a larger study of intervention efficacy. The intervention will be built into an existing, widely-accessed geosocial networking app used by MSM. By building the intervention into a platform already used by millions of individuals, we anticipate that, in the event that the intervention is demonstrated to be efficacious, scale-up of the intervention will be readily achievable. The proposed research seeks to develop mathematical models and an intervention that would reduce the incidence of HIV/AIDS, meeting an overarching research priority identified in the Strategic Plan of the NIH Office of AIDS Research.

项目摘要/摘要 众所周知，一些艾滋病毒预防干预措施是有效的：艾滋病毒检测和与护理的联系 适当的避孕套使用和艾滋病毒暴露前预防(PrEP)。不幸的是，要充分利用 这些预防服务一直具有挑战性。在中国，男男性行为者(MSM)是唯一 风险群体艾滋病毒病例检测增加，占2014年新诊断病例的26%。一种方法 获得更多的预防干预使用将帮助个人了解他们应该在什么时候 使用某些预防服务，并减轻获取服务的负担。拟议的研究 将涉及进行文献回顾和开发数学模型，以探索不同的场景 为中国地区男男性接触者提供组合式艾滋病预防服务干预。使用来自此的信息 在运动中，我们将开发和试点测试智能手机应用程序中内置的艾滋病毒干预组合。这个 干预措施将包括家庭护理服务，如家庭艾滋病毒自我检测和家庭订购预防措施。 避孕套等产品。如果干预措施被证明是可行和可接受的，试点试验将促进 设计一项更大规模的干预效果研究。干预将被构建到现有的、广泛访问的 MSM使用的地理社交网络应用程序。通过将干预措施构建为一个已被数百万人使用的平台 对于个人，我们预计，如果干预措施被证明是有效的，扩大 这种干预将是可以轻易实现的。拟议的研究旨在开发数学模型和 减少艾滋病毒/艾滋病发病率的干预措施，满足总体研究优先事项 在美国国立卫生研究院艾滋病研究办公室的战略计划中确定。