Integrating a combination HIV prevention intervention into a widely-used geosocial app for Chinese MSM

将艾滋病毒预防综合干预措施纳入中国 MSM 广泛使用的地理社交应用程序中

基本信息

批准号：
10079463
负责人：
Aaron Julius Siegler
金额：
$ 61.64万
依托单位：
EMORY UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-01-23 至 2023-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10079463
关键词：
AIDS prevention AIDS/HIV problem Appointment Behavioral Biological Factors Books Canada Caring China Chinese People Cities Clinic Cross-Sectional Studies Custom Data Data Collection Detection Development Diagnosis Diagnostic Reagent Kits Epidemic Event Exercise Exposure to Focus Groups HIV HIV diagnosis HIV/STD Health Hearing Home Home Care Services Human immunodeficiency virus test Incidence India Individual Intervention Intervention Studies Lubricants Mexico Modeling NIH Office of AIDS Research Nongovernmental Organizations Participant Patients Persons Pilot Projects Population Prevention Process Public Health Research Research Priority Resources Review Literature Risk Schedule Service delivery model Services Sexual Health Strategic Planning Structure Surveys System Testing Time Treatment Efficacy Trust United States Work acceptability and feasibility base cognitive interview cohort condomless anal sex condoms design efficacy study experience high risk home based service home test interest mathematical model meetings men who have sex with men novel pre-exposure prophylaxis prevention service preventive intervention programs public health intervention recruit satisfaction scale up self testing service delivery service intervention service uptake smartphone Application successful intervention tool transmission process

项目摘要

PROJECT SUMMARY/ABSTRACT A number of HIV prevention interventions are known to be effective: HIV testing and linkage to care as appropriate, condom use, and HIV pre-exposure prophylaxis (PrEP). Unfortunately, achieving sufficient use of these prevention services has been challenging. In China, men who have sex with men (MSM) are the only risk group with increasing HIV case detection, representing 26% of new cases diagnosed in 2014. One way to obtain increased prevention intervention use would be to help individuals understand when they should be using certain prevention services, and to make accessing services less burdensome. The proposed research will involve conducting a literature review and developing mathematical models to explore different scenarios of providing a combination HIV prevention service intervention for MSM in China. Using information from this exercise, we will develop and pilot test a combination HIV intervention built into a smartphone app. The intervention will include home care services such as home HIV self-testing and home ordering of prevention products such as condoms. If the intervention proves to be feasible and acceptable, the pilot test will facilitate design of a larger study of intervention efficacy. The intervention will be built into an existing, widely-accessed geosocial networking app used by MSM. By building the intervention into a platform already used by millions of individuals, we anticipate that, in the event that the intervention is demonstrated to be efficacious, scale-up of the intervention will be readily achievable. The proposed research seeks to develop mathematical models and an intervention that would reduce the incidence of HIV/AIDS, meeting an overarching research priority identified in the Strategic Plan of the NIH Office of AIDS Research.

项目摘要/摘要已知许多艾滋病毒预防干预措施是有效的：艾滋病毒测试和与护理的联系适当的，使用避孕套和HIV预防前预防（PREP）。不幸的是，实现了足够的这些预防服务一直具有挑战性。在中国，与男人发生性关系的男人（MSM）是唯一的艾滋病毒病例检测增加的风险组，占2014年诊断的新病例的26％。一种方法获得增加的预防干预使用将是帮助个人了解何时应该使用某些预防服务，并使访问服务减少负担。拟议的研究将涉及进行文献综述和开发数学模型，以探索不同的情况在中国为MSM提供了组合的HIV预防服务干预措施。使用此信息锻炼，我们将开发和试点测试智能手机应用中内置的HIV干预组合。这干预将包括家庭护理服务，例如家庭艾滋病毒自我测试和预防家庭订购避孕套等产品。如果事实证明干预是可行的和可接受的，则试点测试将有助于设计更大的干预功效研究。干预措施将内置在现有的，广泛的访问中 MSM使用的地理社会网络应用。通过将干预措施建立到已经使用的平台上个人，我们预计，如果证明干预是有效的，则干预将很容易实现。拟议的研究旨在开发数学模型和一种干预措施，可以减少艾滋病毒/艾滋病的发病率，达到总体研究优先级在NIH艾滋病研究办公室的战略计划中确定。