Population-based survey of SARS-CoV-2 infection and immune response

基于人群的 SARS-CoV-2 感染和免疫反应调查

• 批准号: 10265685
• 负责人: Aaron Julius Siegler
• 金额: $ 123.3万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-05-27 至 2023-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10265685
• 关键词: AIDS prevention; AIDS/HIV problem; Appointment; Behavioral; Biological Factors; Books; Canada; Caring; China; Chinese People; Cities; Clinic; Cross-Sectional Studies; Custom; Data; Data Collection; Detection; Development; Diagnosis; Diagnostic Reagent Kits; Epidemic; Event; Exercise; Exposure to; Focus Groups; HIV; HIV diagnosis; HIV/STD; Health; Hearing; Home; Home Care Services; Human immunodeficiency virus test; Incidence; India; Individual; Intervention; Intervention Studies; Lubricants; Mexico; Modeling; NIH Office of AIDS Research; Nongovernmental Organizations; Participant; Patients; Persons; Pilot Projects; Population; Prevention; Process; Public Health; Research; Research Priority; Resources; Review Literature; Risk; Schedule; Service delivery model; Services; Sexual Health; Strategic Planning; Structure; Surveys; System; Testing; Time; Treatment Efficacy; Trust; United States; Work; acceptability and feasibility; base; cognitive interview; cohort; condomless anal sex; condoms; design; efficacy study; experience; high risk; home based service; home test; interest; mathematical model; meetings; men who have sex with men; novel; pre-exposure prophylaxis; prevention service; preventive intervention; programs; public health intervention; recruit; satisfaction; scale up; self testing; service delivery; service intervention; service uptake; smartphone Application; successful intervention; tool; transmission process

PROJECT SUMMARY/ABSTRACT To have an optimal response to the COVID-19 epidemic, it is important to understand the proportion of adults in the United States may have the virus that causes COVID-19, and how many have had it in the past and may have immunity. Currently available data are limited because the impact of asymptomatic and mildly symptomatic cases is unclear and many people are unable to access a test due to rationing, or may be otherwise unwilling to go for testing or care. This study will address this problem by conducting a national probability sample, where each address may be selected by chance, to develop estimates of the proportion of adults in the United States that are infected with the virus that causes COVID-19, and the proportion that has had the disease in the past and may now have immunity. We will use home-based testing techniques to facilitate participation in this national study. We will also use surveys to better understand participants in our sample. With these estimates, we will conduct disease modeling to understand different scenarios of the epidemic. We will also develop a website to provide information and data to the public.

项目总结/摘要 为了对COVID-19疫情做出最佳应对，重要的是要了解成年人的比例 在美国可能有导致COVID-19的病毒，有多少人在过去和可能 有豁免权。目前可用的数据是有限的，因为无症状和轻度 有症状的病例尚不清楚，许多人由于配给而无法进行测试，或者可能 否则不愿意去做检查或护理。这项研究将通过开展一项全国性的 概率样本，其中每个地址可能是偶然选择的，以估计 美国成年人感染了导致COVID-19的病毒， 过去得过这种病，现在可能有免疫力。我们将使用基于家庭的测试技术， 促进参与这项国家研究。我们还将使用调查，以更好地了解参与者在我们的 sample.有了这些估计，我们将进行疾病建模，以了解不同的情况下， 疫情我们还将建立一个网站，向公众提供信息和数据。